Data Science For Neuroimaging

Data science methods and tools—including programming, data management, visualization, and machine learning—and their application to neuroimaging research As neuroimaging turns toward data-intensive discovery, researchers in the field must learn to access, manage, and analyze datasets at unprecedented scales. Concerns about reproducibility and increased rigor in reporting of scientific results also demand higher standards of computational practice. This book offers neuroimaging researchers an introduction to data science, presenting methods, tools, and approaches that facilitate automated, reproducible, and scalable analysis and understanding of data. Through guided, hands-on explorations of openly available neuroimaging datasets, the book explains such elements of data science as programming, data management, visualization, and machine learning, and describes their application to neuroimaging. Readers will come away with broadly relevant data science skills that they can easily translate to their own questions. • Fills the need for an authoritative resource on data science for neuroimaging researchers • Strong emphasis on programming • Provides extensive code examples written in the Python programming language • Draws on openly available neuroimaging datasets for examples • Written entirely in the Jupyter notebook format, so the code examples can be executed, modified, and re-executed as part of the learning process

Data science methods and tools—including programming, data management, visualization, and machine learning—and their application to neuroimaging research As neuroimaging turns toward data-intensive discovery, researchers in the field must learn to access, manage, and analyze datasets at unprecedented scales. Concerns about reproducibility and increased rigor in reporting of scientific results also demand higher standards of computational practice. This book offers neuroimaging researchers an introduction to data science, presenting methods, tools, and approaches that facilitate automated, reproducible, and scalable analysis and understanding of data. Through guided, hands-on explorations of openly available neuroimaging datasets, the book explains such elements of data science as programming, data management, visualization, and machine learning, and describes their application to neuroimaging. Readers will come away with broadly relevant data science skills that they can easily translate to their own questions. • Fills the need for an authoritative resource on data science for neuroimaging researchers • Strong emphasis on programming • Provides extensive code examples written in the Python programming language • Draws on openly available neuroimaging datasets for examples • Written entirely in the Jupyter notebook format, so the code examples can be executed, modified, and re-executed as part of the learning process

This book explores various state-of-the-art aspects behind the statistical analysis of neuroimaging data. It examines the development of novel statistical approaches to model brain data. Designed for researchers in statistics, biostatistics, computer science, cognitive science, computer engineering, biomedical engineering, applied mathematics, physics, and radiology, the book can also be used as a textbook for graduate-level courses in statistics and biostatistics or as a self-study reference for Ph.D. students in statistics, biostatistics, psychology, neuroscience, and computer science.

This book enables us to analyze statistically brain imaging data. It is meant for a wide range of researchers interested in biostatistics, data science, and neuroscience. It is useful to understand the background theory of standard software for neuroimaging data analysis.

An overview of theoretical and computational approaches to neuroimaging.

The study of brain function is one of the most fascinating pursuits of m- ern science. Functional neuroimaging is an important component of much of the current research in cognitive, clinical, and social psychology. The exci- ment of studying the brain is recognized in both the popular press and the scienti?c community. In the pages of mainstream publications, including The New York Times and Wired, readers can learn about cutting-edge research into topics such as understanding how customers react to products and - vertisements (“If your brain has a ‘buy button,’ what pushes it?”, The New York Times,October19,2004),howviewersrespondtocampaignads(“Using M. R. I. ’s to see politics on the brain,” The New York Times, April 20, 2004; “This is your brain on Hillary: Political neuroscience hits new low,” Wired, November 12,2007),howmen and womenreactto sexualstimulation (“Brain scans arouse researchers,”Wired, April 19, 2004), distinguishing lies from the truth (“Duped,” The New Yorker, July 2, 2007; “Woman convicted of child abuse hopes fMRI can prove her innocence,” Wired, November 5, 2007), and even what separates “cool” people from “nerds” (“If you secretly like Michael Bolton, we’ll know,” Wired, October 2004). Reports on pathologies such as autism, in which neuroimaging plays a large role, are also common (for - stance, a Time magazine cover story from May 6, 2002, entitled “Inside the world of autism”).

A Primer with MATLAB® and PythonTM present important information on the emergence of the use of Python, a more general purpose option to MATLAB, the preferred computation language for scientific computing and analysis in neuroscience. This book addresses the snake in the room by providing a beginner’s introduction to the principles of computation and data analysis in neuroscience, using both Python and MATLAB, giving readers the ability to transcend platform tribalism and enable coding versatility. Includes discussions of both MATLAB and Python in parallel Introduces the canonical data analysis cascade, standardizing the data analysis flow Presents tactics that strategically, tactically, and algorithmically help improve the organization of code

This book describes methods for statistical brain imaging data analysis from both the perspective of methodology and from the standpoint of application for software implementation in neuroscience research. These include those both commonly used (traditional established) and state of the art methods. The former is easier to do due to the availability of appropriate software. To understand the methods it is necessary to have some mathematical knowledge which is explained in the book with the help of figures and descriptions of the theory behind the software. In addition, the book includes numerical examples to guide readers on the working of existing popular software. The use of mathematics is reduced and simplified for non-experts using established methods, which also helps in avoiding mistakes in application and interpretation. Finally, the book enables the reader to understand and conceptualize the overall flow of brain imaging data analysis, particularly for statisticians and data-scientists unfamiliar with this area. The state of the art method described in the book has a multivariate approach developed by the authors’ team. Since brain imaging data, generally, has a highly correlated and complex structure with large amounts of data, categorized into big data, the multivariate approach can be used as dimension reduction by following the application of statistical methods. The R package for most of the methods described is provided in the book. Understanding the background theory is helpful in implementing the software for original and creative applications and for an unbiased interpretation of the output. The book also explains new methods in a conceptual manner. These methodologies and packages are commonly applied in life science data analysis. Advanced methods to obtain novel insights are introduced, thereby encouraging the development of new methods and applications for research into medicine as a neuroscience.