Delicate Divide

Mechanobiology—the study of the effects of mechanical environments on the biological processes of cells—has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions. To achieve these goals, investigators must be familiar with both the basic concepts of mechanics and the modern tools of cellular/molecular biology. Unfortunately, current literature contains numerous studies that misuse standard mechanical estimations and terminology, or fail to implement appropriate molecular analyses. Therefore, the Mechanobiology Handbook not only presents cutting-edge research findings across various fields and organ systems, but also provides the elementary chapters on mechanics and molecular analysis techniques to encourage cross-field understanding and appropriate planning. Aided by the continuous advancement of research tools in both mechanics and biology, more sophisticated experiments and analyses are possible—thus fueling the growth of the field of mechanobiology. Considering the complexity of the mechanics and the biology of the human body, most of the world of biomechanics remains to be studied. Since the field is still developing, the Mechanobiology Handbook does not force one unified theory, but brings out many different viewpoints and approaches to stimulate further research questions.

This surgical atlas illustrates the various successful thyroid surgery techniques of world-renowned surgeons. Some approaches presented include total thyroidectomy, right thyroid lobectomy, left thyroid lobectomy, minimally invasive approach to thyroidectomy, video-assisted approach to thyroidectomy, and endoscopic approaches, such as the transaxillary approach, bilateral axillo-breast approach (BABA), and trans-oral thyroid surgery (TOEVA). The Atlas is intended for a broader audience than publications for other procedures since thyroidectomy is among the most common neck procedures. The Atlas of Thyroid Surgery will help all surgeons caring for patients with thyroid disease minimize complications and perform successful thyroidectomy.