Demystifying Drugs

Based on extensive participant observation research, a life-history model is presented to explain why very few of those who come into contact with narcotics become problematic consumers; that is make drugs one of the most central elements in their lives. The model covers four stages in the deviant career; two preceding and two subsequent to the individual's narcotics debut. Prohibition and harm reduction as models for intervention are presented, and the implications for drug policy of the life-history model are discussed.

The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the nineteen chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators.

A creature of Jewish mythology, a golem is an animated being made by man from clay and water who knows neither his own strength nor the extent of his ignorance. Like science and technology, the subjects of Harry Collins and Trevor Pinch's previous volumes, medicine is also a golem, and this Dr. Golem should not be blamed for its mistakes - they ...

Have you ever wondered if you calculated your patient’s dosage correctly? Against a backdrop of the growing scrutiny of appropriate dosages, this textbook takes a fresh, new approach to helping health professionals strengthen care to and possibly save the lives of patients living with pain. This easy-to-understand and often humorous book is the most comprehensive to-date on opioid calculations for pain management and palliative care. It carefully walks clinicians through a five-step process for performing opioid conversion calculations in the real-world situations they often see. The book has case examples, simple charts and tables, and practice problems throughout on topics such as:· difficult conversions for methadone, fentanyl, PCA, and neuraxial opioid therapy· conversions between routes and dosage formulations of the same opioids and different opioids· titrating opioid dosages up and down to include dosage change and timing· calculating doses for rescue opioid therapy Written by pain management expert Dr. Mary Lynn McPherson, the book gives helpful tips that practitioners should incorporate into their practices. It is a must for clinicians at all levels: hospice and palliative care physicians, physician’s assistants, nurses, nurse practitioners, and pharmacists. Clinicians will come away with more confidence in doing the calculations, and higher service levels from the improvement in care.

Chronic kidney disease affects approximately 30 million adults in the United States. Demystifying Drug Dosing in Renal Dysfunction supports your clinical decision process with guidance on dosage adjustments and monitoring in renal dysfunction for medications, subpopulations, and renal replacement modalities. This time-saving resource provides helpful tips and support for a range of clinical situations, including: Antiepileptics, Cardiovascular disease, Co-morbidities associated with chronic kidney disease, Critical illness, Infectious diseases, Oncology, Pain management, Pediatrics, Psychiatry, Therapeutic plasma exchange, Transplantation Book jacket.

Searching for the ultimate stimulant? Something you can have on the bus in the morning or in the ambient comfort of your own home? The latest User's Guide - a totally natural and controlled experience - is just what you've been looking for. It contains everything you always wanted to know about drugs but were afraid to ask: The history of recreational drugs, a catalogue of natural highs and pharmaceuticals, the physiological effects, drugs and religion, drugs and the law, drug customs from around the world, trafficking drugs, drugs in literature, film and art, famous drug takers, drug slang, urban myths, drug legends and horror stories, quotations, tales of outrageous behaviour and a kilo of curious facts and figures. Did you know that- --Scientists have found traces of marijuana among Shakespeare's personal effects--Victorian prime minister Lord Rosebery would snort cocaine to help pep up his public speaking

Summarizes knowledge about the characteristics, knowledge, attitudes, and practices of certain audiences of children who are at a higher risk for drug and alcohol abuse. Also discusses channels, sources, materials and messages and offers ideas for reaching these groups. Chapters cover the general category of youth from high-risk environments, looking specifically at Black and Hispanic/Latino children, and influences on them such as parents and primary care physicians. Includes case studies, messages and materials review process, and intermediary organizations.