Dendrimer Chemistry

An overview of the latest advances in the synthesis, characterization and applications of dendrimers and other complex dendritic architectures.

Written by internationally acclaimed authors, this textbook contains everything you need to know about this versatile class of compounds. Starting with a historical overview, definitions and other fundamentals, it goes on to look at characterization, analysis and properties of dendrimers. While the focus is on synthesis and applications, it also contains chapters on analytics and other applications. Essential reading for organic and polymer chemists, undergraduate and graduate students, students and lecturers in chemistry.

Following the first two volumes "Dendrimers" (TCC vol. 197) and "Dendrimers II" (TCC vol. 210), the third volume dealing with this topic is now appearing in print (the "tetralogy" on dendrimers will soon be completed with the fourth volume). The present volume comprises a collection of up-to-date reviews written by renowned pioneers of research in the dendrimer field, three of whom lectured at the 1. International Dendrimer Symposium (IDS-1 1999) in Frankfurt. A focus of this volume is the variety of material properties of soft and shape-persistent dendrimers. As its predecessors did, this volume breaks through the frontiers to neighboring disciplines and, in an interdisciplinary approach, addresses topics such as polydisperse, hyperbranched macromolecules (dendritic polymers), the analysis of shape and density by small-angle scattering techniques, finely dispersed metals (dendrimers as catalysts), and nanotechnology close to potential applications.

The unique structures and properties of dendrimers make them attractive for many applications, from drug delivery and antimicrobial agents to catalysis and as functional materials. Dendrimer Chemistry provides an overview of the latest advances in the synthesis of dendrimers and other complex dendritic architectures. The book focuses on established building block families for generating dendritic macromolecules, capitalizing on the evolution in the synthesis of dendrimers and other complex dendritic architectures. Systems covered range from dendritic polyesters and naturally occurring monomers to novel dendritic families. Each chapter starts with an introduction to the dendrimer family and its important features followed by information on the building blocks used to generate the dendrimers, their synthetic strategies and the resulting architectures. Chapters also cover the characterization and structural analysis, commercial availability and cutting-edge applications. Including forewords from leaders in the field, this will be a useful reference for postgraduate students and researchers in organic chemistry, polymer chemistry, materials science and macromolecular chemistry.

With contributions from many of the world's leading scientists in the field of dendritic research and development, Dendrimers and Other Dendritic Polymers provides a comprehensive review of this rapidly expanding and exciting new field of polymer science. Of interest to academia and industry alike, this book covers the synthesis, characterization, unique properties, potential for novel applications and technical challenges associated with these polymers. * Detailed coverage of all known subclasses of dendritic polymers, including their properties and synthesis * Insight into the potential commercial applications of dendritic polymers, including drug delivery, cancer therapy, coatings and adhesives * Identification of the key trends and perspectives in dendrimer research * Essential reference for polymer chemists, materials scientists and plastics engineers working in academia and industry alike

Dendrimers are important molecules that are currently undergoing investigation for use in a variety of different biomedical applications. This book explores the use of dendrimers for a variety of potential functions, including antiamyloidogenic agents, drug delivery systems, nucleic acid and RNA delivery vectors and to produce hybrid fibre platforms for nantechnology. Following the work of COST action TD0802, the main objective of which is to improve existing therapies and find new drugs based on dendrimers, the book will provide comprehensive coverage of dendrimer applications. Coverage includes modelling and molecular dynamic studies of dendrimers and dendrons, anionic dendrimer polymers, cationic carbosilane dendrimers and self-assembled multivalent dendrimers. Providing clear indications for future research and applications, this text will appeal to chemists, biologists and materials scientists, working in both academia and industry.

The second volume on dendrimers is again written by pioneers in the field. Their contributions illuminate the aspects of dendrimers mentioned in the subtitle, and also touch on areas beyond chemistry, namely material sciences as well as biological, medicinal, analytical, and nano aspects.

This book provides a comprehensive summary and critical overview of a topic in organometallic chemistry. Research in this rapidly developing transdisciplinary field is having profound influence on other areas of scientific investigation, ranging from catalytic organic synthesis to biology, medicine and material science. The book is complemented by a review of metallodendritic exoreptors for the redox recognition of oxo-anions and halides.