Dendrites

Dendrites form the major receiving part of neurons. This text presents a survey of knowledge on dendrites, from their morphology and development, through to their electrical chemical, and computational properties.

Neuronal dendritic trees are complex structures that endow the cell with powerful computing capabilities and allow for high neural interconnectivity. Studying the function of dendritic structures has a long tradition in theoretical neuroscience, starting with the pioneering work by Wilfrid Rall in the 1950s. Recent advances in experimental techniques allow us to study dendrites with a new perspective and in greater detail. The goal of this volume is to provide a résumé of the state-of-the-art in experimental, computational, and mathematical investigations into the functions of dendrites in a variety of neural systems. The book first looks at morphological properties of dendrites and summarizes the approaches to measure dendrite morphology quantitatively and to actually generate synthetic dendrite morphologies in computer models. This morphological characterization ranges from the study of fractal principles to describe dendrite topologies, to the consequences of optimization principles for dendrite shape. Individual approaches are collected to study the aspects of dendrite shape that relate directly to underlying circuit constraints and computation. The second main theme focuses on how dendrites contribute to the computations that neurons perform. What role do dendritic morphology and the distributions of synapses and membrane properties over the dendritic tree have in determining the output of a neuron in response to its input? A wide range of studies is brought together, with topics ranging from general to system-specific phenomena—some having a strong experimental component, and others being fully theoretical. The studies come from many different neural systems and animal species ranging from invertebrates to mammals. With this broad focus, an overview is given of the diversity of mechanisms that dendrites can employ to shape neural computations.

Studies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians.

This indispensable resource draws on the latest research in brain-based learning to provide strategies that motivate adult learners and increase retention.

Get Novelty Back Into The Classroom To Get Knowledge Into Students’ Brains! In this thoroughly updated third edition of Marcia Tate’s bestseller, you’ll learn about twenty definitive brain-compatible techniques to maximize retention and minimize forgetting in learners of all ages. Tate’s techniques are drawn from the latest neuroscientific research and learning style theory and are described step-by-step for immediate application in your classroom. Learn how to: Incorporate interactive fun to your existing lessons, including field trips, games, humor, and even music and rap Use graphic organizers and word webs to solidify lessons visually Facilitate innovative methods of project-based learning

Dendrites are complex neuronal structures that receive and integrate synaptic input from other nerve cells. They therefore play a critical role in brain function. Although dendrites were discovered over a century ago, due to the development of powerful new techniques there has been a dramatic resurgence of interest in the properties and function of these beautiful structures. This is the third edition of the first book devoted exclusively to dendrites. It contains a comprehensive survey of the current state of dendritic research across a wide range of topics, from dendritic morphology, evolution, development, and plasticity through to the electrical, biochemical and computational properties of dendrites, and finally to the key role of dendrites in brain disease. The third edition has been thoroughly revised, with each chapter updated or completely rewritten by leading experts, plus the addition of a number of new chapters. "Dendrites" will be of interest to researchers and students in neuroscience and related fields, as well as to anyone interested in how the brain works.

Dendrites are complex neuronal structures that receive and integrate synaptic input from other nerve cells. They therefore play a critical role in brain function. Although dendrites were discovered over a century ago, due to the development of powerful new techniques there has been a dramatic resurgence of interest in the properties and function of these beautiful structures. This is the third edition of the first book devoted exclusively to dendrites. It contains a comprehensive survey of the current state of dendritic research across a wide range of topics, from dendritic morphology, evolution, development, and plasticity through to the electrical, biochemical and computational properties of dendrites, and finally to the key role of dendrites in brain disease. The third edition has been thoroughly revised, with the addition of a number of new chapters and comprehensive updates or rewrites of existing chapters by leading experts. "Dendrites" will be of interest to researchers and students in neuroscience and related fields, as well as to anyone interested in how the brain works.

"Tate and Phillips provide research-based strategies that will shape your students′ learning. From music to graphics to technology, they show educators how to incorporate methods that will excite students and make science memorable." —Emily Neddersen, Lead Science Teacher, Myford Elementary School, Tustin, CA A brain-friendly guide for motivating students to live, eat, and breathe science! Best-selling author and renowned educator Marcia L. Tate brings her trademark practicality to teachers seeking the latest brain-compatible tools for engaging students and bringing science to life in the classroom. Co-authored with award-winning science teacher Warren G. Phillips, this must-have resource includes 20 proven brain-compatible strategies and 250 activities for applying them. Teachers will find concrete ways to integrate national science content standards into their curriculum with visual, auditory, kinesthetic, and tactile experiences that maximize retention, including: Music, rhythm, rhyme, and rap Storytelling and humor Graphic organizers, semantic maps, and word webs Manipulatives, experiments, labs, and models Internet and Excel projects The book covers a full range of K–12 science subjects, including physical, life, earth and space science, and provides brain-compatible sample lesson plans. Each chapter offers real-life examples; a what, why, and how for each strategy; activities; and note pages for brainstorming how to implement these exciting new ideas.