Designing The Perfect R Sum

Experimental design is often overlooked in the literature of applied and mathematical statistics: statistics is taught and understood as merely a collection of methods for analyzing data. Consequently, experimenters seldom think about optimal design, including prerequisites such as the necessary sample size needed for a precise answer for an experi

Learn how to use R to turn raw data into insight, knowledge, and understanding. This book introduces you to R, RStudio, and the tidyverse, a collection of R packages designed to work together to make data science fast, fluent, and fun. Suitable for readers with no previous programming experience, R for Data Science is designed to get you doing data science as quickly as possible. Authors Hadley Wickham and Garrett Grolemund guide you through the steps of importing, wrangling, exploring, and modeling your data and communicating the results. You'll get a complete, big-picture understanding of the data science cycle, along with basic tools you need to manage the details. Each section of the book is paired with exercises to help you practice what you've learned along the way. You'll learn how to: Wrangle—transform your datasets into a form convenient for analysis Program—learn powerful R tools for solving data problems with greater clarity and ease Explore—examine your data, generate hypotheses, and quickly test them Model—provide a low-dimensional summary that captures true "signals" in your dataset Communicate—learn R Markdown for integrating prose, code, and results

Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors’ many years of experience in academia and the pharmaceutical industry. While the focus is on nonlinear models, the book begins with an explanation of the key ideas, using linear models as examples. Applying the linearization in the parameter space, it then covers nonlinear models and locally optimal designs as well as minimax, optimal on average, and Bayesian designs. The authors also discuss adaptive designs, focusing on procedures with non-informative stopping. The common goals of experimental design—such as reducing costs, supporting efficient decision making, and gaining maximum information under various constraints—are often the same across diverse applied areas. Ethical and regulatory aspects play a much more prominent role in biological, medical, and pharmaceutical research. The authors address all of these issues through many examples in the book.

This textbook provides a concise introduction to optimal experimental design and efficiently prepares the reader for research in the area. It presents the common concepts and techniques for linear and nonlinear models as well as Bayesian optimal designs. The last two chapters are devoted to particular themes of interest, including recent developments and hot topics in optimal experimental design, and real-world applications. Numerous examples and exercises are included, some of them with solutions or hints, as well as references to the existing software for computing designs. The book is primarily intended for graduate students and young researchers in statistics and applied mathematics who are new to the field of optimal experimental design. Given the applications and the way concepts and results are introduced, parts of the text will also appeal to engineers and other applied researchers.

This book is the first of a series which focuses on the interpolation and extrapolation of optimal designs, an area with significant applications in engineering, physics, chemistry and most experimental fields. In this volume, the authors emphasize the importance of problems associated with the construction of design. After a brief introduction on how the theory of optimal designs meets the theory of the uniform approximation of functions, the authors introduce the basic elements to design planning and link the statistical theory of optimal design and the theory of the uniform approximation of functions. The appendices provide the reader with material to accompany the proofs discussed throughout the book.

Devoted to a unified optimality theory, merging three otherwise distinct mathematical disciplines to embrace an astonishingly wide variety of design problems. Outlines typical settings, namely D-, A-, and E-optimal, polynominal regression designs, Bayesian designs, structures for model discrimination, balanced incomplete block arrangements or rotatable response surface designs. The design problems stem from statistics but are solved using special tools from linear algebra and convex analysis.

This book introduces multi-objective design methods to solve multi-objective optimization problems (MOPs) of linear/nonlinear dynamic systems under intrinsic random fluctuation and external disturbance. The MOPs of multiple targets for systems are all transformed into equivalent linear matrix inequality (LMI)-constrained MOPs. Corresponding reverse-order LMI-constrained multi-objective evolution algorithms are introduced to solve LMI-constrained MOPs using MATLAB®. All proposed design methods are based on rigorous theoretical results, and their applications are focused on more practical engineering design examples. Features: Discusses multi-objective optimization from an engineer’s perspective Contains the theoretical design methods of multi-objective optimization schemes Includes a wide spectrum of recent research topics in control design, especially for stochastic mean field diffusion problems Covers practical applications in each chapter, like missile guidance design, economic and financial systems, power control tracking, minimization design in communication, and so forth Explores practical multi-objective optimization design examples in control, signal processing, communication, and cyber-financial systems This book is aimed at researchers and graduate students in electrical engineering, control design, and optimization.