Developmental Origins Of Health And Disease
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Developmental Origins of Health and Disease
Author | : Peter Gluckman,Mark Hanson |
Publsiher | : Cambridge University Press |
Total Pages | : 542 |
Release | : 2006-04-20 |
Genre | : Medical |
ISBN | : 0521847435 |
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This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances.
Epigenetics
Author | : Joel D. Wallach,Ma Lan,Gerhard N. Schrauzer |
Publsiher | : SelectBooks, Inc. |
Total Pages | : 443 |
Release | : 2014-05 |
Genre | : Health & Fitness |
ISBN | : 9781590792551 |
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WHAT IS EPIGENETICS? Epigenetics is an emerging field of science that studies alterations in gene expression caused by factors other than changes in the DNA sequence. Epigenetics: The Death of the Genetic Theory of Disease Transmission is the result of decades of research and its findings that could be as critical to our understanding of human health as Pasteur’s research in bacteriology. Dr. Joel “Doc” Wallach has dedicated his life work to identifying connections between certain nutritional deficiencies and a range of maladies, formerly thought to be hereditary, including Cystic Fibrosis and Muscular Dystrophy. This nexus between nutrition and so-called genetic disease has been observed in both humans and primates, and it is the central theme of Epigenetics. To bring us Epigenetics, Wallach has teamed with noted scholars Dr. Ma Lan and Dr. Gerhard N. Schrauzer. Their collective expertise gives this book its far reaching perspective. Epigenetics is of vital importance to anyone who wants real knowledge about how the human body functions, and it provides a path for better health. Epigentics dispels the dogma and misinformation propagated by medical institutions and doctors resistant to change. Epigenetics is the beginning of a new era of well-being on this planet.
Developmental Origins of Health and Disease DOHaD
Author | : Takeo Kubota,Hideoki Fukuoka |
Publsiher | : Springer |
Total Pages | : 95 |
Release | : 2018-06-28 |
Genre | : Medical |
ISBN | : 9789811055263 |
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This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonatal periods, and that earlier prevention and intervention would result in better outcomes for adult diseases such as type 2 diabetes and cardiac disorders, which are increasing in both developed and developing countries. The book appeals to obstetricians and pediatricians, as well as physicians who treat adult patients, wanting to understand the origins of diseases.
Developmental Origins of Health and Disease
Author | : Lucilla Poston,Keith Godfrey,Sir Peter Gluckman,Mark Hanson |
Publsiher | : Cambridge University Press |
Total Pages | : 239 |
Release | : 2022-12-31 |
Genre | : Medical |
ISBN | : 9781009272247 |
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Fully revised new edition highlighting the scientific and clinical advances in the field of developmental origins of health and disease. Explores new understanding of mechanisms such as epigenetics and the role of environmental influences on the fetus. Interventions throughout the lifespan and implications for public health are also covered.
Disease Control Priorities Third Edition Volume 5
Author | : Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent |
Publsiher | : World Bank Publications |
Total Pages | : 466 |
Release | : 2017-11-17 |
Genre | : Medical |
ISBN | : 9781464805202 |
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Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.
Early Life Origins of Human Health and Disease
Author | : John P. Newnham,Michael G. Ross |
Publsiher | : Karger Medical and Scientific Publishers |
Total Pages | : 233 |
Release | : 2009-01-01 |
Genre | : Medical |
ISBN | : 9783805591393 |
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There is compelling evidence that many of the risks leading to the most frequent chronic diseases in adulthood originate in the earliest stages of life. Adverse environmental conditions in utero and during infancy can lead to negative health effects during the subsequent lifetime of the exposed individual.This book offers precious insights into the latest concepts and results from epidemiologic, clinical and basic studies in this burgeoning area of health care. The developmental origins of various diseases such as diabetes, obesity and cancer are examined, as well as the early programming of reproductive health and different organs. Attention is given to the impact of environmental factors such as nutrition and pollution, and the mediating genetic and epigenetic pathways are reviewed. A crucial point under discussion is the concept of environmental insults adversely affecting not only the exposed persons, but also their descendants. In addition, the economic consequences of a suboptimal start to life and the importance of preventive measures are stressed.This publication is of great value to anyone interested in health care, notably to specialists in obstetrics, pediatrics, internal medicine, obesity, diabetes and heart disease.
Epigenetics of Aging and Longevity
Author | : Alexey Moskalev,Alexander M. Vaiserman |
Publsiher | : Academic Press |
Total Pages | : 544 |
Release | : 2017-11-17 |
Genre | : Medical |
ISBN | : 9780128110836 |
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Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan
The Routledge Handbook of Anthropology and Reproduction
Author | : Sallie Han,Cecília Tomori |
Publsiher | : Routledge |
Total Pages | : 631 |
Release | : 2021-11-09 |
Genre | : Social Science |
ISBN | : 9781000455984 |
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The Routledge Handbook of Anthropology and Reproduction is a comprehensive overview of the topics, approaches, and trajectories in the anthropological study of human reproduction. The book brings together work from across the discipline of anthropology, with contributions by established and emerging scholars in archaeological, biological, linguistic, and sociocultural anthropology. Across these areas of research, consideration is given to the contexts, conditions, and contingencies that mark and shape the experiences of reproduction as always gendered, classed, and racialized. Over 39 chapters, a diverse range of international scholars cover topics including: Reproductive governance, stratification, justice, and freedom. Fertility and infertility. Technologies and imaginations. Queering reproduction. Pregnancy, childbirth, and reproductive loss. Postpartum and infant care. Care, kinship, and alloparenting. This is a valuable reference for scholars and upper-level students in anthropology and related disciplines associated with reproduction, including sociology, gender studies, science and technology studies, human development and family studies, global health, public health, medicine, medical humanities, and midwifery and nursing.