Diagnostic Pediatric Cytopathology And Histopathologic Correlation

Written as a response to the increasing utilization of minimally invasive procedures in children, this state-of-the art book provides a comprehensive review of pediatric cytopathology with histopathologic correlation, focussing particularly on those entities unique to the pediatric population and highlighting differences between children and adult patients. As most pathologic diagnoses require knowledge of clinical presentation and or imaging features, these are integral parts of the work-up in each chapter. This comprehensive guide provides optimal use of the newest diagnostic techniques (including molecular, genetic and immunohistochemical studies) to help overcome diagnostic challenges. The book is illustrated with more than 1000 high-quality color images and a password in each copy of the book provides the reader with full electronic access to all text and images. This book will provide a practical resource for practicing pediatric pathologists and cytopathologists, and a valuable educational tool for the residents and fellows in training.

This text presents serious challenges for trainees, clinicians, and practicing pathologists and cytopathologists due to the wide spectrum of diagnoses that may be seen in children and the lack of familiarity with these entities. This reference book has been designed as a practical, high-yield review of pediatric cytopathology. Key findings are highlighted and up-to-date information is provided on the diagnosis of pediatric lesions by cytology, with extensive guidance on differential diagnosis. The book includes tables and full-color images of the cytomorphology and ancillary studies, as well as pertinent histological correlation and guidance on technical issues. Pediatric Cytopathology: A Practical Guide will be an essential reference for anyone interested in the cytomorphological findings in childhood diseases.

This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.

The Second Edition of The Milan System for Reporting Salivary Gland Cytopathology, like the First Edition, represents a collaborative effort by a multidisciplinary group of cytopathologists, surgical pathologists, molecular pathologists, radiologists, and head and neck surgeons. This international group shares the goal of creating a practical and uniform reporting system for salivary gland fine needle aspiration (FNA). This book is organized into six general diagnostic categories: “Non-Diagnostic,” “Non-Neoplastic,” “Atypia of Undetermined Significance (AUS),” “Neoplasm: Benign,” “Neoplasm: Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP),” “Suspicious for Malignancy,” and “Malignant.” It includes definitions, morphologic criteria, and explanations for each of the diagnostic categories. Specific chapters are dedicated to the application of the latest available ancillary studies, radiologic features of salivary gland lesions, clinical management, and histological considerations including updates from the most recent 5th Edition WHO blue book. The Milan System for Reporting Salivary Gland Cytopathology 2nd Edition represents an essential step towards increasing the overall effectiveness of salivary gland FNA and fostering better communication between clinicians and between institutions to improve overall patient care.

This richly illustrated book will help presurgically diagnose pediatric/young adult tumors. The content is divided into two parts. The first part shows step-by-step how to perform a small volume specimen such as fine needle aspiration/core needle biopsy and how to correlate the morphology with the clinical, radiological, and/or molecular information. In turn, the second part presents a comprehensive overview of the various tumor entities. The content represents diagnostic modalities from the major diagnostic centers worldwide, and is supplemented by the authors` 25 years of experience in diagnosing pediatric tumors. This book will successfully guide practitioners, researchers and oncology pediatricians through the process of sample harvesting and diagnosing. Pediatric tumors represent a large variety of lesions including pseudotumors of inflammatory and non-inflammatory origin, various types of lympadenopathy, benign lesions, specific sarcomas, and blastemal malignancies. These age-specific and histotype-specific tumors of various origin, evolution and prognosis are often characteristic in morphological and molecular levels, making their diagnosis highly specialized.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cytopathology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. Covers all areas of cytopathology, including clinical, radiologic, and immunohistochemical as well as cytopathologic features and molecular correlates where applicable Contains new chapters on ancillary molecular tests specific to thyroid, prognostic/therapy-related immunomarkers in cell blocks, and small biopsies Provides new immunohistochemical and molecular coverage, including new immunostains and genomic targets Incorporates new reporting terminology (such as serous fluid and effusions) and updates to existing reporting terminologies Reflects the expanded use of fine-needle aspiration for small biopsies (FNA-B) with many more images added and updated throughout Keeps you up-to-date with current and emerging reporting systems on pancreaticobiliary, salivary, breast, and soft tissue cytology Features more than 3,000 print and online images, including carefully annotated histology and gross pathology photos, full-color illustrations, clinical photographs, and radiologic images to help practicing and in-training pathologists reach a confident diagnosis Includes new videos on such topics as the cytoprepratory process, cell transfer cell block and smears, collodion bag cell block, and more Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert cytopathology reference at the point of care

The new edition of Diagnostic Cytopathology provides the practicing and trainee cytopathologist with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book covers normal and abnormal cytological findings encountered in all body sites where cytological applications are used. Appropriate histopathological, immunohistochemical and molecular correlations, together with a consideration of the possible differential diagnoses, accompany the cytological findings. The reader can see a full range of normal and abnormal findings with almost 2,000 full-colour images. The book is heavily referenced to ensure that it will serve as a practical resource for daily reference in the laboratory. A uniformity of basic chapter structure will help readers to quickly find the diagnostic answers they seek. This edition stresses not just the diagnostic cytological features of the various conditions encountered, but also the diagnostic pitfalls and the grey areas between so as to enable the reader to give more evidence-based reports. In recognition of their rapid expansion, there are new chapters on recent technological developments and on the cytodiagnosis of childhood tumours. A special section on the importance of multidisciplinary team meetings that include the cytopathologist as a core member of the team has also been included at the end of each chapter. As active members of this team, cytopathologists can define their role in the management pathway and thus bring the patient and the microscope together as never before. The full text can be accessed online and images downloaded via Expert Consult.

Exfoliative and instrumented (catheterized) urines are the most common types of specimens evaluated in a cytology laboratory. The typical clinical presentation is a patient with new onset of urinary symptoms, asymptomatic hematuria, or patient with prior history of urothelial carcinoma on routine surveillance. A careful examination of exfoliated cells from the urinary tract can lead to a fast, relatively simple, economical and accurate cytopathologic diagnosis, which is crucial for timely patient management. However, there are a number of common non-neoplastic reactive conditions that can morp.