Electrical Properties Of Tissues

This book covers the latest developments in tissue electrical conductivity and current density imaging, increasingly popular as well as challenging applications of MRI. These applications are enabled by the acquisition of high-quality MR phase images. This book provides a practical description of the MRI physics needed to understand and acquire phase images in MRI and the key details required to reconstruct them into conductivity, current density or electric field distributions. Comprehensive details are provided about the electrical properties of biological tissues, computational modeling considerations, experimental methods, construction of non-biological and biological phantoms and MRI pulse sequences. An inclusive review of image reconstruction algorithms, and their potential applications is provided for applications directed at determining current density or electric fields, such as in transcranial DC or AC stimulation techniques; as well as electrical conductivity reconstructions that may be of use in quantitative MRI applications used to detect cancer or other pathologies. This is an excellent book for undergraduate and graduate students beginning to explore phase, current density, and conductivity imaging in MRI, and will also be of great use to researchers interested in the area of MR-based electrical property imaging.

This unique reference book describes quantitatively the measured and predicted values of all the physical properties of mammalian tissue. Reported measurements are thoroughly documented and are complemented by a range of empirical mathematical models which describe the observed physical behavior of tissue.**Intended as a broad-ranging reference, this volume gives the bioengineer, physicist, radiologist, or physiologist access to a literature which may not be known in detail. It will also be of value for those concerned with the study of a range of environmental radiation hazards. Most extensive compilation of values of physical properties of tissue**Presents data for thermal, optical, ultrasonic, mechanical, x-ray, electrical, and magnetic resonance properties**Comprehensive bibliography

This is the first book that presents a comprehensive introduction to and overview of electro-magnetic tissue property imaging techniques using MRI, focusing on Magnetic Resonance Electrical Impedance Tomography (MREIT), Electrical Properties Tomography (EPT) and Quantitative Susceptibility Mapping (QSM). The contrast information from these novel imaging modalities is unique since there is currently no other method to reconstruct high-resolution images of the electro-magnetic tissue properties including electrical conductivity, permittivity, and magnetic susceptibility. These three imaging modalities are based on Maxwell's equations and MRI data acquisition techniques. They are expanding MRI's ability to provide new contrast information on tissue structures and functions. To facilitate further technical progress, the book provides in-depth descriptions of the most updated research outcomes, including underlying physics, mathematical theories and models, measurement techniques, computation issues, and other challenging problems. Contents:IntroductionElectro-magnetism and MRIMagnetic Resonance Electrical Impedance TomographyMR-EPTQuantitative Susceptibility Mapping Readership: Researchers, academics and graduate students in medical imaging, computational mathematics and biomedical imaging. Keywords:Inverse Problem;MREIT;EPT;QSM;Conductivity;Permittivity;Susceptibility

This book describes the basic electrical properties of a variety of mammalian tissues in scientific terms that even a student who has had little formal training in the physics of electricity should find understandable.

The North Atlantic Treaty Organization (NATO) has sponsored research supporting development of personnel safety standards for exposure to Radio Frequency Radiation (RFR) for over a quarter century. NATO previously recognized that one of the most important tools used in the RFR effects research laboratory is accurate dosimetry when it supported a NATO Advanced Studies Institute (ASI) on Advances in Biological Effects and Dosimetry of Low Energy Electromagnetic Fields held in 1981, in Erice, Sicily. That meeting resulted in a NATO ASI publication; Biological Effects and Dosimetry of l Non-ionizing Radiation: Radiofrequency and Microwave Energies . The most recent NATO sponsored program on RFR was an Advanced Research Workshop (ARW) on "Developing a New Standardization Agreement (STANAG) for Radio frequency Radiation" held May 1993, at the Pratica di Mare Italian Air Force Base, Pomezia (Rome) Italy. That ARW produced an ASI proceedings, published in 1995: Radio frequency Radiation Standards, Biological Effects, Dosimetry, Epidemiology, and Public Health Policy2. The Rome ARW and the Proceedings served as a springboard to the much needed revision of the NATO Standardization Agreement (STANAG) 2345 MED "Evaluation and Control of Personnel Exposure to Radio Frequency Fields - 3 kHz to 300 GHz,,3, which was subsequently promulgated in October 1998. One of the published recommendations developed by the Rome ARW was to hold this second ARW focusing on dosimetry and measurements.

Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.

This book presents an overview of the field of bioelectricity by demonstrating the biological significance of electromagnetic fields, electrical properties of tissue, biological effects of electromagnetic energy, and therapeutic applications and health hazards of electromagnetic energy.

Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes – in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.