Esophageal Cancer And Beyond

Human life relies on two basic supplies from nature: oxygen and food. Oxygen can be utilized directly, but food has to go through a process of digestion to become usable nutrients. The esophagus represents the beginning of this long journey. Because of its critical location, esophageal cancer is one of the deadliest malignancies in the world, and furthermore its incidence has been rising steadily year after year while other cancers are declining. It is predicted that by the year 2035 the esophageal cancer population will increase by 77.4% and become one of top global concerns. This book covers many aspects of esophageal cancer, through which we hope to raise the awareness of professionals as well as non-professionals about this disease.

Human life relies on two basic supplies from nature: oxygen and food. Oxygen can be utilized directly, but food has to go through a process of digestion to become usable nutrients. The esophagus represents the beginning of this long journey. Because of its critical location, esophageal cancer is one of the deadliest malignancies in the world, and furthermore its incidence has been rising steadily year after year while other cancers are declining. It is predicted that by the year 2035 the esophageal cancer population will increase by 77.4% and become one of top global concerns. This book covers many aspects of esophageal cancer, through which we hope to raise the awareness of professionals as well as non-professionals about this disease.

Despite progress, esophageal cancer survival rates vary significantly. Early detection plays a crucial role. Unfortunately, symptoms like heartburn can be mistaken for less serious issues, leading to later diagnosis when the cancer is more aggressive. Additionally, socioeconomic factors can impact access to quality healthcare and optimal treatment options. Research also suggests disparities in screening and awareness between different demographics. Closing this survival gap requires a multi-pronged approach. Public awareness campaigns can educate people about early warning signs. Improved access to healthcare, particularly in underserved communities, is vital. Additionally, ongoing research into early detection methods and personalized treatment plans holds promise for narrowing the gap and offering a more hopeful future for all esophageal cancer patients.

Gastrointestinal endoscopy is the principal tool for the investigation and treatment of most diseases of the gastrointestinal tract. The Atlas of Clinical Gastrointestinal Endoscopy offers a comprehensive overview of the role of gastrointestinal endoscopy in diagnosis. The atlas contains an abundance of high-quality images of a wide range of diseases of the upper and lower gastrointestinal tract, accompanied by precise clinical descriptions. Normal findings and variants are also documented. Furthermore, many images obtained by means of advanced image-enhanced endoscopy, capsule endoscopy, device-assisted enteroscopy, and endoscopic ultrasound are included. This book will be an ideal reference for both specialists and trainees in gastroenterology. It will provide the reader with an invaluable store of knowledge and with the clear guidance required in order to perform gastrointestinal endoscopy to best effect.

The leading reference text entirely devoted to this increasinglysignificant condition This text is dedicated to Barrett’s esophagus and providesrecent evidence and current approaches to patient management. Ithas been completely revised, updated and extended to include thelatest research findings and describes how these affect day-to-dayclinical practice. It includes seven new chapters and even more color images thanthe last edition. Each chapter, written by the leadinginternational experts in the field, provides clear, didacticguidance on diagnosis, treatment and management of thiscondition. Barrett’s Espohagus gives an extensive overviewcovering epidemiology, screening, pathology, gastroenterology andsurgery. It looks at the precursor lesions leading to thedevelopment of Barrett’s epithelium, the uniquecharacteristics of Barrett’s esophagus, and the consequencesof malignant degeneration. All aspects of diagnosis, secondaryprevention, multimodality, and medical and surgical treatment areclearly explained. This is a complete guide on the latest thinking on diagnosis andtreatment of Barrett’s esophagus which can be referred toover and over again.

This book discusses the main stem cell niches under distinct pathophysiological conditions. The role of tissue microenvironments in stem cell regulation, as well as modern methodologies and new techniques for the identification and characterization of stem cell niches, are discussed by leading experts in the field. Chapters describe the major components of various stem cell microenvironments, such as cellular components, soluble factors, cell-cell interactions, extra-cellular matrix proteins, and physical forces. Stem Cell Microenvironments and Beyond is part of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students and researchers in the field of stem cells or cell biology as well as clinicians.

Human life relies on two basic supplies, oxygen and food. Oxygen can be utilized directly, but food has to go through a long process of digestion to become usable nutrients. The esophagus is the beginning part of this long journey. Because of its critical location, any abnormalities in this part of the body can be devastating and life-threatening and difficult to treat. This book covers many aspects of esophageal disorders, from congenital diseases to cancer. It includes 11 chapters written by highly experienced scholars from all over the world. It is our intention to provide readers an update in esophageal study and to raise the awareness how important this organ to our entire body system.

Among the deadliest type of cancers, lung cancer faces several challenges in diagnosis and treatment: late diagnosis and misdiagnosis, inadequate tumor sampling, and resistance development to current therapies, among others. Together with advances in the understanding of molecular features, factors, and mechanisms involved in initiation and tumor progression, important improvements have occurred in diagnostics and therapeutics in the shape of advances in molecular genotyping, procedures for sampling, new potential, and less invasive sources of samples for the diagnosis and development of new targeted therapies. The aim of this book is to provide an exciting read on strategies in the diagnosis and therapy of lung cancer.