Eugene Braunwald And The Rise Of Modern Medicine

Much of the improved survival rate from heart attack can be traced to Eugene Braunwald's work. He proved that myocardial infarction was an hours-long dynamic process which could be altered by treatment. Thomas H. Lee tells the life story of a physician whose activist approach transformed not just cardiology but the culture of American medicine.

Much of the improved survival rate from heart attack can be traced to Eugene Braunwald's work. He proved that myocardial infarction was an hours-long dynamic process which could be altered by treatment. Thomas H. Lee tells the life story of a physician whose activist approach transformed not just cardiology but the culture of American medicine.

Since the 1950s, the death rate from heart attacks has plunged from 35 percent to about 5 percent--and fatalistic attitudes toward this disease and many others have faded into history. Much of the improved survival and change in attitudes can be traced to the work of Eugene Braunwald, MD. In the 1960s, he proved that myocardial infarction was not a "bolt from the blue" but a dynamic process that plays out over hours and thus could be altered by treatment. By redirecting cardiology from passive, risk-averse observation to active intervention, he helped transform not just his own field but the culture of American medicine. Braunwald's personal story demonstrates how the forces of history affected the generation of researchers responsible for so many medical advances in the second half of the twentieth century. In 1938 Nazi occupiers forced his family to flee Vienna for Brooklyn. Because of Jewish quotas in medical schools, he was the last person admitted to his class, but went on to graduate number one. When the Doctor Draft threatened to interrupt his medical training during the Korean War, he joined the National Institutes of Health instead of the Navy, and there he began the research that made him the most influential cardiologist of his time. In Eugene Braunwald and the Rise of Modern Medicine, Thomas H. Lee offers insights that only authoritative firsthand interviews can provide, to bring us closer to this iconic figure in modern medicine.

Seven million people die from cancer each year around the world, and many more are impacted by this universal scourge. In Betrayed by Nature, research scientist and lecturer Robin Hesketh demystifies the nature of cancer. Hesketh provides a concise and comprehensive history of both the science and the medical advances made over the decades. He takes the reader on a riveting tour of human biology; he explains how cancers start, what is meant by ‘a mutation', and how mutations can make cells grow abnormally and spread around our bodies. Drawing on the latest discoveries from the Human Genome Project, Hesketh reveals the strides being made in understanding this malevolent disease and makes accessible the science of today's treatments. Betrayed by Nature looks forward to the day when many cancers can be treated readily and effectively. With cancer afflicting one in three people worldwide, this is an illuminating and optimistic look at the past, present, and future of cancer.

This book is a biography of the physician Galen of Pergamum (A.D. 129 - ca. 216), who began his remarkable career tending to wounded gladiators in provincial Asia Minor. Later in life he achieved great distinction as one of a small circle of court physicians to the family of Emperor Marcus Aurelius, at the very heart of Roman society. --From publisher's description.

At the turn of the twentieth century, smallpox claimed the lives of two million people per year. By 1979, the disease had been eradicated and victory was declared across the globe. Yet the story of smallpox remains the exception, as today a host of deadly contagions, from polio to AIDS, continue to threaten human health around the world. Spanning three centuries, The End of Plagues weaves together the discovery of vaccination, the birth and growth of immunology, and the fight to eradicate the world's most feared diseases. From Edward Jenner's discovery of vaccination in 1796, to the early nineteenth-century foundling voyages in which chains of orphans, vaccinated one by one, were sent to colonies around the globe, to the development of polio vaccines and the stockpiling of smallpox as a biological weapon in the Cold War, world-renown immunologist John Rhodes charts our fight against these plagues, and shows how vaccinations gave humanity the upper hand. Today, aid groups including the Bill and Melinda Gates Foundation and the World Health Organization have made the eradication of polio a priority, and Rhodes takes us behind the scenes to witness how soon we may be celebrating the eradication of polio.

Two leading physicians' prescription for solving our health care problems: organizing the fragmented system that delivers care. One of the most daunting challenges facing the new U.S. administration is health care reform. The size of the system, the number of stakeholders, and ever-rising costs make the problem seem almost intractable. But in Chaos and Organization in Health Care, two leading physicians offer an optimistic prognosis. In their frontline work as providers, Thomas Lee and James Mongan see the inefficiency, the missed opportunities, and the occasional harm that can result from the current system. The root cause of these problems, they argue, is chaos in the delivery of care. If the problem is chaos, the solution is organization, and in this timely and outspoken book, they offer a plan. In many ways, this chaos is caused by something good: the dramatic progress in medical science—the explosion of medical knowledge and the exponential increase in treatment options. Imposed on a fragmented system of small practices and individual patients with multiple providers, progress results in chaos. Lee and Mongan argue that attacking this chaos is even more important than whether health care is managed by government or controlled by market forces. Some providers are already tightly organized, adapting management principles from business and offering care that is by many measures safer, better, and less costly. Lee and Mongan propose multiple strategies that can be adopted nationwide, including electronic medical records and information systems for sharing knowledge; team-based care, with doctors and other providers working together; and disease management programs to coordinate care for the sickest patients.

In his time the most famous physician in the world, Canadian-born William Osler (1849-1919) is still the best-known figure in the history of medicine. This new, definitive biography by Michael Bliss is the first full-scale life of Osler to appear since 1925. An award-winning medical historian, Bliss draws on many untapped sources to recreate Osler's life and medical times for a new generation of readers. Born at Bond Head, north of Toronto, Osler rose from obscurity to become the greatest medical teacher and writer in three countries. At Canada's McGill University, America's Johns Hopkins University, and finally as regius professor at Oxford, Osler was idolized by two generations of medical students and practitioners, for whom he came to personify the ideal doctor. His quest was to bring high standards and scientific methods into general practice in the medical world and to give teaching hospitals a solid place in the education of doctors. The publication of his book, The Principles and Practice of Medicine (1892), established him as the authority of modern medicine, a position he held well into the new century. Osler was revered as the high priest of the advent of twentieth-century medicine. In this fine biography, Michael Bliss animates the epic quality of Osler's life - not only in telling his personal story, but in setting that story against the dramatic backdrop of the coming of modern medicine. Winner of the Jason A. Hannah Medal, awarded by the Royal Society of Canada and the Hannah Institute for the History of Medicine