Exocrine Pancreatic Cancer

Exocrine Pancreatic Cancer
Author: Hughes Baumel,Bernard Deixonne
Publsiher: Springer Science & Business Media
Total Pages: 336
Release: 2012-12-06
Genre: Medical
ISBN: 9783642711787

Download Exocrine Pancreatic Cancer Book in PDF, Epub and Kindle

For a long time, approximately since Oberlin and Guerin described the multifocal origin of pancreatic cancers and precancerous pancreatic lesions, no important study dealing with the entire subject of pancreatic cancer has been published in France and probably in the international literature. For some decades the knowl edge acquired 40years or more ago was not improved appreciably, though the fre quency ofthe disease started to increase in occidental countries. This has recently changed, and the progress ofthe medical sciences has spread to the pancreas. Although the surgical or medical prognosis of the most frequent form of pancreatic cancer, exocrine adenocarcinoma, remains very bad, recent studies have shown the multiplicityofits pathological forms, some being less severe so that curative surgery is possible. New experimental models, particularly in the hamster, and the use of carcinogenic drugs allow experimental studies on lesions similar to those in man. Oncologic immunology is still at its beginnings but shows promise for diagnosis and treatment. Though modem techniques of imaging sonography, aspirative cytology, CT scan, endoscopic catheterism, arteriography, and maybe in the future nuclear magnetic resonance - have not yet significantly in fluenced prognosis, they have made the diagnosis easierand more precocious. Yet in a diseasethat diffuses so rapidly to deep lymph nodes, it has not been proved whether early diagnosis can improve prognosis.

Atlas of Exocrine Pancreatic Tumors

Atlas of Exocrine Pancreatic Tumors
Author: Parviz M. Pour,Yoichi Konishi,Günter Klöppel,Daniel S. Longnecker
Publsiher: Springer Science & Business Media
Total Pages: 451
Release: 2012-12-06
Genre: Medical
ISBN: 9784431683117

Download Atlas of Exocrine Pancreatic Tumors Book in PDF, Epub and Kindle

The classification of tumors is important for understanding tumor histogenesis, for predicting prognosis, for differential diagnosis, and for recommending appropriate therapy. Since 1836, when pancreatic cancer was first described, progress has been made in pancreatic cancer morphology, and a number of classifications have been proposed. All of these classifications are mainly based on morphological characteristics. Some are too detailed to be of practical use while others are more pragmatic. Some of the inherent problems in the previous classifications included difficulties in obtaining an adequate number of pan creatic tumors for examination and insufficient clinical data and follow-up. With the increasing incidence of pancreatic cancer in many parts of the world during the past six decades, and with the availability of more tumors to patho logists, advances have been made in pancreatic tumor studies. Classifications by Cubilla and Fitzgerald and by Kloppel, which are generally similar, mostly considered prominent morphological features and their histogenesis. These pathology-oriented classifications, although complete, were not practical from the standpoint of clinicians concerned with the prognosis of individual tumors.

The Exocrine Pancreas

The Exocrine Pancreas
Author: Stephen Pandol
Publsiher: Morgan & Claypool Publishers
Total Pages: 66
Release: 2011
Genre: Medical
ISBN: 9781615041381

Download The Exocrine Pancreas Book in PDF, Epub and Kindle

The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.

Clinical Pancreatology for Practising Gastroenterologists and Surgeons

Clinical Pancreatology for Practising Gastroenterologists and Surgeons
Author: Juan Enrique Dominguez-Munoz
Publsiher: John Wiley & Sons
Total Pages: 752
Release: 2021-03-17
Genre: Medical
ISBN: 9781119570141

Download Clinical Pancreatology for Practising Gastroenterologists and Surgeons Book in PDF, Epub and Kindle

Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.

Atlas of Exocrine Pancreatic Tumors

Atlas of Exocrine Pancreatic Tumors
Author: Parviz M. Pour
Publsiher: Springer
Total Pages: 287
Release: 1994-01-01
Genre: Pancreas
ISBN: 354070129X

Download Atlas of Exocrine Pancreatic Tumors Book in PDF, Epub and Kindle

Exocrine Pancreas Cancer

Exocrine Pancreas Cancer
Author: Thomas Mathias Gress
Publsiher: Unknown
Total Pages: 531
Release: 2005
Genre: Electronic Book
ISBN: 3000163727

Download Exocrine Pancreas Cancer Book in PDF, Epub and Kindle

Molecular Pathogenesis of Pancreatic Cancer

Molecular Pathogenesis of Pancreatic Cancer
Author: Thomas M. Gress
Publsiher: IOS Press
Total Pages: 124
Release: 2000
Genre: Pancreas
ISBN: 158603040X

Download Molecular Pathogenesis of Pancreatic Cancer Book in PDF, Epub and Kindle

This book was written to summarize the midterm meeting of the concerted action BMH4-CT98-3085 funded by the European Union in the context of the BIOMEDII programme. The objective of this concerted action (CA) is to generate a European network allowing to share expertise, technologies and resources to speed up the process of characterization of potential new disease genes in pancreatic cancer. The meeting in Barcelona in November 1999 was hosted by the group at the IMIM led by F.X. Real, and was scheduled to allow a midterm evaluation of the individual projects.

Clinical Small Animal Internal Medicine

Clinical Small Animal Internal Medicine
Author: David Bruyette
Publsiher: John Wiley & Sons
Total Pages: 4856
Release: 2020-03-25
Genre: Medical
ISBN: 9781118497036

Download Clinical Small Animal Internal Medicine Book in PDF, Epub and Kindle

Clinical Small Animal Internal Medicine is a comprehensive, practical reference designed to meet the needs of veterinary practitioners and students alike. Covering all aspects of small animal internal medicine, this innovative guide provides clinically relevant material, plus podcasts and continual updates online. Concise, identically-formatted chapters allow readers to quickly find the most essential information for clinical veterinary practice. Contributions from academic and clinical experts cover general medicine subjects, including patient evaluation and management, critical care medicine, preventative care, and diagnostic and therapeutic considerations. Topics relevant to daily clinical practice are examined in detail, ranging from endocrine, cardiovascular, respiratory, and infectious disease to oncology, dermatology, metabolic orthopedic disease, gastroenterology, and hepatology. A companion website features podcasts and updated information. An important addition to the library of any practice, this clinically-oriented text: Presents complete, practical information on small animal internal medicine Provides the background physiology required to understand normal versus abnormal in real-world clinical settings Includes general medicine topics not covered in other internal medicine books Focuses on information that is directly applicable to daily practice Features podcasts and continual updates on a companion website Carefully tailored for the needs of small animal practitioners and veterinary students, Clinical Small Animal Internal Medicine is an invaluable, reader-friendly reference on internal medicine of the dog and cat.