Experimental Animal Models Of Human Diseases
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Experimental Animal Models of Human Diseases
Author | : Bartholomew Ibeh |
Publsiher | : BoD – Books on Demand |
Total Pages | : 410 |
Release | : 2018-05-23 |
Genre | : Science |
ISBN | : 9781789231649 |
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The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.
Experimental Animal Models of Human Diseases
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Author | : Ibeh Bartholomew |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 2018 |
Genre | : Animal models in research |
ISBN | : 1838812601 |
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Experimental Animal Models of Human Diseases An Effective Therapeutic Strategy
![Experimental Animal Models of Human Diseases An Effective Therapeutic Strategy](https://youbookinc.com/wp-content/uploads/2024/06/cover.jpg)
Author | : Ibeh Bartholomew |
Publsiher | : Unknown |
Total Pages | : 408 |
Release | : 2018 |
Genre | : Zoology |
ISBN | : 1789231655 |
Download Experimental Animal Models of Human Diseases An Effective Therapeutic Strategy Book in PDF, Epub and Kindle
The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.
Use of Laboratory Animals in Biomedical and Behavioral Research
Author | : National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research |
Publsiher | : National Academies Press |
Total Pages | : 113 |
Release | : 1988-02-01 |
Genre | : Science |
ISBN | : 9780309038393 |
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Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Animal Models for the Study of Human Disease
Author | : P. Michael Conn |
Publsiher | : Academic Press |
Total Pages | : 1108 |
Release | : 2013-05-29 |
Genre | : Science |
ISBN | : 9780124159129 |
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Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease
Spontaneous Animal Models of Human Disease
Author | : Edwin J. Andrews,Billy C. Ward,Norman H. Altman |
Publsiher | : Elsevier |
Total Pages | : 345 |
Release | : 2012-12-02 |
Genre | : Science |
ISBN | : 9780323138284 |
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This two-volume work gathers together the diverse information presently available on spontaneous animal models of human disease. In addition to providing a comprehensive review of existing models, the book presents many previous unpublished new models.The scope of this work is limited to spontaneous models. Neoplasia, infectious diseases including parasitism, and nutritionally induced or other types of experimental models have not been included. The sixteen parts of the book are alphabetically arranged according to organ system with over 230 authors contributing to the overall effort. In addition to many illustrations, the book features an extensive bibliography.
Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents
Author | : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Board on Life Sciences,Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents |
Publsiher | : National Academies Press |
Total Pages | : 87 |
Release | : 2006-08-07 |
Genre | : Political Science |
ISBN | : 9780309180900 |
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The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies-including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)-be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.
Sourcebook of Models for Biomedical Research
Author | : P. Michael Conn |
Publsiher | : Springer Science & Business Media |
Total Pages | : 756 |
Release | : 2008-03-07 |
Genre | : Medical |
ISBN | : 9781597452854 |
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The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.