Fast Facts Renal Disorders

Early detection of renal problems coupled with the appropriate therapeutic strategy can radically reduce the progressive nature of, and complications associated with, chronic kidney disease, and in many instances will result in the successful treatment of acute kidney injury. As many patients will not be seen by nephrologists, it is essential that all healthcare professionals, in hospitals and in the community, have an awareness of renal disease – the presenting signs, differential diagnoses, treatment strategies and approach to the management of complications. 'Fast Facts: Renal Disorders' is an easy-to-read, evidence-based guide to renal diseases and disorders for all doctors, nurses and medical students. It includes: • A clear explanation of proteinuria, hematuria, electrolyte imbalances and acid–base disorders • A concise summary of kidney function tests, imaging techniques and biopsy • Important questions for prompt diagnosis of acute kidney injury • Management options for chronic kidney disease and its complications • Practical guidance on the most common renal problems, including glomerulonephritis, systemic disease, UTIs and kidney stones Written by three specialists of international repute, 'Fast Facts: Renal Disorders' provides the key information required for the optimal care of renal patients. This fully updated second edition will help healthcare professionals assess, identify, treat and refer patients with renal problems appropriately. Directly applicable to the clinical setting, it is essential reading for all primary care providers, junior hospital doctors, specialist trainees, renal nurses and medical students. Contents: • Proteinuria, hematuria and renal investigations • Electrolyte disturbances and acid–base disorders • Acute kidney injury • Chronic kidney disease • Hypertension and diabetic nephropathy • Glomerulonephritis • Systemic disease • Inherited kidney disease • Urinary tract infection • Kidney stones • Urinary tract obstruction and tumors • Renal replacement therapy and transplantation

Kidney disease is common, and its prevalence is increasing worldwide. Current statistics suggest that up to 8% of the population in developed countries have some degree of renal impairment. The economic and social consequences are enormous.Early detection coupled with the appropriate therapeutic strategy can radically reduce the progressive nature and complications associated with chronic kidney disease and successfully treat acute renal failure in many instances.It is essential that all physicians, both in hospitals and in the community, have an awareness of renal disease - the presenting signs, differential diagnoses, treatment strategies and approach to the management of complications.- An expert, factual presentation of exactly the information required to provide optimal care for patients- Three specialists of international repute present a clear and concise account of each disease state- Key points summarized at each chapter-end- Comprehensively illustrated - concise and directly applicable in the clinical setting

The term ‘bladder disorders’ encompasses a number of lower urinary tract dysfunctions and abnormalities that negatively affect quality of life. Some can cause considerable morbidity and even mortality. Three internationally recognized authors with different areas of expertise – a leading British urogynecologist, a chief of urology listed as one of America's "Best Doctors", and an American continence expert - have ensured that this second edition of 'Fast Facts: Bladder Disorders' is internationally relevant to the non-specialist working within a multidisciplinary team. Based on robust evidence and clinical experience, and supported by superb illustrations, this fact-filled handbook covers everything you will need to recognize the symptoms and signs of a wide range of bladder disorders from urinary incontinence to hematuria to UTIs. It also provides an excellent overview of basic pathophysiology, and will help practitioners initiate screening and assessment and, where appropriate, treatment. Contents: • Anatomy and function of the urinary system • Assessment • Urinary incontinence • The overactive bladder and urgency incontinence • Voiding problems • Hematuria • Urinary tract infections and cystitis • Nocturnal symptoms • Neuropathic bladder dysfunction • Special considerations • Useful resources

Most hemorrhagic problems are emergencies, requiring rapid diagnosis and prompt management to stop bleeding. In some cases, such as nose bleeds, large bruises and heavy menses, it is the clinician’s responsibility to discern whether the patient has a clinically significant bleeding disorder that may predispose to excessive or potentially serious bleeding. 'Fast Facts: Bleeding Disorders' keeps a complex subject simple and clinically oriented. The authors have made numerous updates to this second edition to ensure it provides essential information in a readily accessible format. Highlights include: • An expert overview of normal hemostasis • A clear assessment pathway, from taking an accurate history and focused clinical examination, to essential laboratory investigations • Objective criteria for diagnosing hereditary hemorrhagic telangiectasia • The latest guidelines on diagnosing and treating primary immune thrombocytopenia • A discussion of the benefits of prophylaxis in patients with hemophilia • Updated methods for evaluating and treating bleeding disorders in pregnancy • An overview of the scoring system for disseminated intravascular coagulation • Information on the latest anticoagulants and antithrombotics, including bleeding risks and strategies to control bleeding. 'Fast Facts: Bleeding Disorders' remains a comprehensive up-to-date reference that reflects the latest research and clinical guidelines. It will assist primary care providers, physician assistants, nurse-clinicians, pharmacists, residents and doctors in training as they confront the challenges of controlling bleeding in patients with hemophilia, von Willebrand disease, platelet disorders and thrombosis, or as a result of antithrombotic or anticoagulant therapy. It is a small book packed with important information, designed to swiftly improve patient treatment and outcomes. Contents: • Normal hemostasis • Assessment of bleeding symptoms • Vascular purpuras • Platelet disorders • Pharmacological hemostatic products • Hemophilia • von Willebrand disease • Uncommon congenital coagulation disorders • Liver and kidney disorders • Pregnancy • Perioperative bleeding • Disseminated intravascular coagulation • Anticoagulants and antithrombotic agents • Useful resources

Hypertension is the biggest cause of death and disability in the world, yet it remains underdiagnosed, undertreated and, in many cases, poorly controlled. As in the previous edition, 'Fast Facts: Hypertension' advises on: • accurate measurement of blood pressure and problems such as 'white-coat' hypertension • routine assessments for people with high blood pressure • other modifiable risk factors (smoking, high cholesterol levels etc.) • non-pharmacological measures (reducing salt, losing weight, increasing physical activity etc.) • rational and effective use of all drug treatments • identification of people with secondary hypertension • treatment of children, pregnant women, the elderly and patients with diabetes. Updates in this new edition include: • distinguishing between patients with primary (low renin) and secondary aldosteronism • greater use of home BP measurement in clinical decision-making • the latest thinking on BP treatment thresholds • new guidance on fourth-line therapy for resistant hypertension Sometimes dubbed 'the silent killer', hypertension rarely produces symptoms until it manifests as a heart attack or stroke, so early identification of the condition and appropriate management are vital. This practical readable refresher for every-day use supports better investigation and treatment of high blood pressure by primary care providers and better self-management by patients. Contents: • The dangers of raised blood pressure • Causes • Investigation • When to treat • How to treat • Special patient groups • Uncontrolled hypertension • Useful resources

With rising levels of alcohol consumption, obesity and viral hepatitis infection, liver disease is presenting more and more frequently in general practice. Health professionals need to be adept at isolating the cause of disease and initiating prompt action. 'Fast Facts: Liver Disorders' is designed to help primary care providers, hospital doctors and specialist nurses understand the most important issues as quickly as possible, including the indicators of severe disease in order to identify patients who need specialist referral. This succinct, practical handbook provides quick access to: • an organized approach to the interpretation of liver function tests • guidance on determining levels of alcohol consumption • the latest hepatitis B and C treatments • key information on the complications of cirrhosis • an overview of the common clinical problems associated with transplantation With its simple explanations, clear illustrations and logical algorithms, 'Fast Facts: Liver Disorders' will help you identify and correct liver disease, minimize permanent damage, and monitor and manage recovery within the community. Contents: • Investigating liver disease • Acute liver disease • Alcoholic liver disease • Drug-induced liver injury • Autoimmune liver diseases • Metabolic liver diseases • Chronic viral hepatitis • Complications of cirrhosis • Benign liver tumors, cysts, infections and abscesses • Hepatocellular carcinoma • Pregnancy and the liver • Liver transplantation

Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care

The only current resource for APPs caring for people with SUDs in clear, concise format This greatly needed resource is the first to provide evidence-based information and strategies for APRNs and PAs who work with individuals with substance use disorders (SUDs). Written in a concise, bulleted style for easy access to critical information, the reference addresses often-undiagnosed medical and psychiatric conditions which may accompany SUDs and the ethical considerations of working with affected patients and families. Written by noted substance abuse experts, the resource distills key information about SUDs, explaining what they are and what they are not, and the role of APPs in helping afflicted individuals to recover. It discusses how to identify SUDs regarding signs and symptoms, emergency response, and specific disorders. Also addressed is the use of pharmacology to treat SUDs including complementary and alternative medications, person-centered care for individuals with SUDs across the lifespan, and how to care for afflicted individuals in a variety of settings. Key Features: Distills current, evidence-based information in a concise, bulleted, pocket-sized format Organized for quick access to information Delivers proven strategies for successful nursing interventions Defines substance abuse disorders across the lifespan Discusses how to de-stigmatize people with substance abuse disorders Explores legal and ethical implications surrounding provision of health care to patients with SUDs