Fetal Physiology And Medicine

Fetal Physiology and Medicine: The Basis of Perinatology, Second, Revised Edition documents many of the major advances in fetal medicine, including developmental physiology, pathology, and therapy. This book covers the most important areas of maternofetal medicine and presents different views of the critical problems of development. The various components of fetal metabolism are highlighted to demonstrate how animal experimentation has given a clear view of the interrelationship of the mother, placenta, and fetus. This text is comprised of 24 chapters; the first of which describes the use of ultrasound in antenatal diagnosis of congenital structural anomalies. This topic is followed by a discussion on sexual differentiation, acquired immunity, and endocrine changes, as well as the physiology of breathing, the control of the fetal cardiovascular system, lung maturation, fetal infections, and the effects of hypoxia on the fetal brain. This book also provides comprehensive reviews of fetal regulatory mechanisms, such as the reninangiotensin system, water metabolism, and fetal and placental hormone production. Other chapters focus on clinical applications, such as antenatal fetal heart rate monitoring, the technical aspects of fetal and uterine pressure measurements, fetal acid-base balance, and the prevention of preterm delivery. A section that explores the transition from intrauterine to extrauterine life concludes this book. This source is of great potential value to all students and practitioners of reproductive medicine.

This second edition offers an expanded and updated history of the field of fetal and neonatal development, allowing readers to gain a comprehensive understanding of the biological aspects that contribute to the wellbeing or pathophysiology of newborns. In this concluding opus of a long and prominent career as a clinical scientist, Dr. Longo has invited new contributions from noted colleagues with expertise in various fields to provide a historical perspective on the impact of how modern concepts emerged in the field of fetal physiology and contributed to the current attention paid to the fetal origins of diseases in adults. In addition to new chapters on maternal physiology and complications during pregnancy, others trace the history of the Society for Reproductive Investigation, governmental funding of perinatal research, and major initiatives to support training in the new discipline of maternal fetal medicine, including the Reproductive Scientist Development program. The extensive survey provided by the author, who personally knew most of the pioneers in the field, offers a unique guide for all clinical and basic scientists interested in the history of – and future approaches to diagnosing and treating – pathologies that represent the leading causes of neonatal mortality and, far too often, life-long morbidity.

To celebrate the Center for Perinatal Biology’s 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease.

Covering pertinent basic science and offering today’s most authoritative guidance on clinical management, Fetal Medicine, 3rd Edition, is a must-have resource for obstetricians and other healthcare professionals involved in care of the fetus. An international team of expert contributors delivers the knowledge and background you need to effectively diagnose and treat fetal disorders – everything from prenatal screening and diagnostic tests to common and rare prenatal conditions, early pregnancy loss, ethical issues, and much more. Focuses on fetal medicine throughout, bringing you today’s most reliable information in both basic science and clinical topics. Offers updated information from cover to cover, including new coverage of genetics, embryology, and clinical management. Features new self-assessment questions and new images throughout – for a total of nearly 1,000 photographs and line drawings, as well as more than 150 quick-reference tables. Details fast-changing developments in fetal medicine, including advances in ultrasound imaging, cytogenetics, molecular biology, and biochemistry. Helps you learn and retrieve complex information quickly thanks to succinct, highly structured text; key points at the beginning of each chapter; and concise chapter summaries.

Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors. 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place. In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.

Offering the comprehensive, authoritative information needed for effective diagnosis, treatment, and management of sick and premature infants, Fetal and Neonatal Physiology, 6th Edition, is an invaluable resource for board review, clinical rounds, scientific research, and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into definitive guidance for today's busy practitioner, focusing on the basic science needed for exam preparation and key information required for full-time practice. It stands alone as the most complete text available in this complex and fast-changing field, yet is easy to use for everyday application. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Contains new chapters on Pathophysiology of Genetic Neonatal Disease, Genetic Variants and Neonatal Disease, and Developmental Biology of Lung Stem Cells, as well as significantly revised chapters on Cellular Mechanisms of Neonatal Brain Injury, Neuroprotective Therapeutic Hypothermia, Enteric Nervous System Development and Gastrointestinal Motility, and Physiology of Twin-Twin Transfusion. Features 1,000 full-color diagrams, graphs and anatomic illustrations, 170+ chapters, and more than 350 global contributors. Includes chapters devoted to clinical correlation that help explain the implications of fetal and neonatal physiology, as well as clinical applications boxes throughout. Provides summary boxes at the end of each chapter and extensive cross-referencing between chapters for quick reference and review. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

To celebrate the Center for Perinatal Biology’s 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease.

Forlagets beskrivelse: This two-volume book comprises an up-to-date reference text on fetal and neonatal physiology. It contains 190 chapters written by experts in each field which provide essential background information as well as contemporary viewpoints and research. The purpose of this second edition is to bring current information to readers and to enlarge the original scope with a more comprehensive approach. It is targeted to fellows, nurses, and other personnel training in fetal and neonatal medicine as well as to established investigators. Overall, the volumes accomplish their purpose. The topics are appropriately divided and indexed and nearly all of the chapters can be read at a single sitting. The illustrations are good, but their impact would have been improved by using more color. Chapters related to my specialty were well written and highly readable. These included placental development, developmental hematopoiesis, and developmental immunobiology. Disappointingly, immune relationships between the mother and baby during pregnancy, now a matter of considerable interest to fetal and neonatal physiologists, are not discussed. Nor were interactions between the immune, endocrine, and nervous systems highlighted. Although the book suffers from the previously mentioned problems and other minor deficiencies, it is nonetheless a notable achievement and is likely to be a standard volume on the shelves of novice and experienced physiologists.