Foundations Of Clinical Research

Become a successful evidence-based practitioner. How do you evaluate the evidence? Is the information accurate, relevant and meaningful for clinical decision making? Did the design fit the research questions and was the analysis and interpretation of data appropriate? Here are all the materials you need to take your first steps as evidence-based practitioners…how to use the design, data and analysis of research as the foundation for effective clinical decision making. You’ll find support every step of the way as you progress from the foundations of clinical research and concepts of measurement through the processes of designing studies and analyzing data to writing their own research proposal.

Foundations of Clinical Research: Applications to Practice, 3/e provides the foundations that are necessary for finding and interpreting research evidence across all healthcare professions. This book has been revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, including the growing emphasis on evidence-based practice (EBP) that has become central to all of health care and the new vocabulary that is being integrated into research and practice across disciplines. There is also a new chapter on systematic reviews and meta-analysis as well as expanded content related to clinical decision making, including likelihood ratios, pretest and posttest probabilities, minimally important change and number needed to treat.

Foundations of Clinical Research: Applications to Practice, 3/e serves as a comprehensive reference for a variety of research situations. This edition reflects the contemporary focus on evidence-based practice in health care, and the essential concepts for understanding analysis and research design. Expanded topics include measures of diagnostic accuracy, statistical estimates of validity and reliability, systematic reviews and meta-analysis, search strategies and critical appraisal of literature for clinical decision making and development of research. Written for those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology, this text will be useful to developing clinicians, practitioners, graduate students and researchers.

This book focuses on the practical application of good clinical practice (GCP) fundamentals and provides insight into roles and responsibilities included in planning, executing, and analyzing clinical trials. The authors describe the design of quality into clinical trial planning and the application of regulatory, scientific, administrative, business, and ethical considerations. Describes the design of quality into the clinical trial planning Has end-of-chapter questions and answers to check learning and comprehension Includes charts that visually summarize the content and allow readers to cross-reference details in relevant chapters Offers a companion website containing supplemental training resources