Functions Selection And Mechanisms

This volume handles in various perspectives the concept of function and the nature of functional explanations, topics much discussed since two major and conflicting accounts have been raised by Larry Wright and Robert Cummins’ papers in the 1970s. Here, both Wright’s ‘etiological theory of functions’ and Cummins’ ‘systemic’ conception of functions are refined and elaborated in the light of current scientific practice, with papers showing how the ‘etiological’ theory faces several objections and may in reply be revisited, while its counterpart became ever more sophisticated, as researchers discovered fresh applications for it. Relying on a firm knowledge of the original positions and debates, this volume presents cutting-edge research evincing the complexities that today pertain in function theory in various sciences. Alongside original papers from authors central to the controversy, work by emerging researchers taking novel perspectives will add to the potential avenues to be followed in the future. Not only does the book adopt no a priori assumptions about the scope of functional explanations, it also incorporates material from several very different scientific domains, e.g. neurosciences, ecology, or technology. In general, functions are implemented in mechanisms; and functional explanations in biology have often an essential relation with natural selection. These two basic claims set the stage for this book’s coverage of investigations concerning both ‘functional’ explanations, and the ‘metaphysics’ of functions. It casts new light on these claims, by testing them through their confrontation with scientific developments in biology, psychology, and recent developments concerning the metaphysics of realization. Rather than debating a single theory of functions, this book presents the richness of philosophical issues raised by functional discourse throughout the various sciences.​

This accessible book presents a new theory of biological functions and connects it to contemporary problems in philosophy and science.

Scientists studying the burning of stars, the evolution of species, DNA, the brain, the economy, and social change, all frequently describe their work as searching for mechanisms. Despite this fact, for much of the twentieth century philosophical discussions of the nature of mechanisms remained outside philosophy of science. The Routledge Handbook of Mechanisms and Mechanical Philosophy is an outstanding reference source to the key topics, problems, and debates in this exciting subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors, the Handbook is divided into four Parts: Historical perspectives on mechanisms The nature of mechanisms Mechanisms and the philosophy of science Disciplinary perspectives on mechanisms. Within these Parts central topics and problems are examined, including the rise of mechanical philosophy in the seventeenth century; what mechanisms are made of and how they are organized; mechanisms and laws and regularities; how mechanisms are discovered and explained; dynamical systems theory; and disciplinary perspectives from physics, chemistry, biology, biomedicine, ecology, neuroscience, and the social sciences. Essential reading for students and researchers in philosophy of science, the Handbook will also be of interest to those in related fields, such as metaphysics, philosophy of psychology, and history of science.

In Neurocognitive Mechanisms Gualtiero Piccinini presents the most systematic, rigorous, and comprehensive philosophical defence to date of the computational theory of cognition. His view posits that cognition involves neural computation within multilevel neurocognitive mechanisms, and includes novel ideas about ontology, functions, neural representation, neural computation, and consciousness. He begins by defending an ontologically egalitarian account of composition and realization, according to which all levels are equally real. He then explicates multiple realizability and mechanisms within this ontologically egalitarian framework, defends a goal-contribution account of teleological functions, and defends a mechanistic version of functionalism. This provides the foundation for a mechanistic account of computation, which in turn clarifies the ways in which the computational theory of cognition is a multilevel mechanistic theory supported by contemporary cognitive neuroscience. Piccinini argues that cognition is computational at least in a generic sense. He defends the computational theory of cognition from standard objections, yet also rebuts putative a priori arguments. He contends that the typical vehicles of neural computations are representations, and that, contrary to the received view, the representations posited by the computational theory of cognition are observable and manipulatable in the laboratory. He also contends that neural computations are neither digital nor analog; instead, neural computations are sui generis. He concludes by investigating the relation between computation and consciousness, suggesting that consciousness may be a functional phenomenon without being computational in nature. This book will be of interest to philosophers of cognitive science as well as neuroscientists.

T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.

This volume brings together new papers advancing contemporary debates in foundational, conceptual, and methodological issues in cognitive neuroscience. The different perspectives presented in each chapter have previously been discussed between the authors, as the volume builds on the experience of Neural Mechanisms (NM) Online – webinar series on the philosophy of neuroscience organized by the editors of this volume. The contributed chapters pertain to five core areas in current philosophy of neuroscience. It surveys the novel forms of explanation (and prediction) developed in cognitive neuroscience, and looks at new concepts, methods and techniques used in the field. The book also highlights the metaphysical challenges raised by recent neuroscience and demonstrates the relation between neuroscience and mechanistic philosophy. Finally, the book dives into the issue of neural computations and representations. Assembling contributions from leading philosophers of neuroscience, this work draws upon the expertise of both established scholars and promising early career researchers.