Fundamentals Of Machine Learning And Deep Learning In Medicine

This book provides an accessible introduction to the foundations of machine learning and deep learning in medicine for medical students, researchers, and professionals who are not necessarily initiated in advanced mathematics but yearn for a better understanding of this disruptive technology and its impact on medicine. Once an esoteric subject known to few outside of computer science and engineering departments, today artificial intelligence (AI) is a widely popular technology used by scholars from all across the academic universe. In particular, recent years have seen a great deal of interest in the AI subfields of machine learning and deep learning from researchers in medicine and life sciences, evidenced by the rapid growth in the number of articles published on the topic in peer-reviewed medical journals over the last decade. The demand for high-quality educational resources in this area has never been greater than it is today, and will only continue to grow at a rapid pace. Expert authors remove the veil of unnecessary complexity that often surrounds machine learning and deep learning by employing a narrative style that emphasizes intuition in place of abstract mathematical formalisms, allowing them to strike a delicate balance between practicality and theoretical rigor in service of facilitating the reader’s learning experience. Topics covered in the book include: mathematical encoding of medical data, linear regression and classification, nonlinear feature engineering, deep learning, convolutional and recurrent neural networks, and reinforcement learning. Each chapter ends with a collection of exercises for readers to practice and test their knowledge. This is an ideal introduction for medical students, professionals, and researchers interested in learning more about machine learning and deep learning. Readers who have taken at least one introductory mathematics course at the undergraduate-level (e.g., biostatistics or calculus) will be well-equipped to use this book without needing any additional prerequisites.

This textbook presents deep learning models and their healthcare applications. It focuses on rich health data and deep learning models that can effectively model health data. Healthcare data: Among all healthcare technologies, electronic health records (EHRs) had vast adoption and a significant impact on healthcare delivery in recent years. One crucial benefit of EHRs is to capture all the patient encounters with rich multi-modality data. Healthcare data include both structured and unstructured information. Structured data include various medical codes for diagnoses and procedures, lab results, and medication information. Unstructured data contain 1) clinical notes as text, 2) medical imaging data such as X-rays, echocardiogram, and magnetic resonance imaging (MRI), and 3) time-series data such as the electrocardiogram (ECG) and electroencephalogram (EEG). Beyond the data collected during clinical visits, patient self-generated/reported data start to grow thanks to wearable sensors’ increasing use. The authors present deep learning case studies on all data described. Deep learning models: Neural network models are a class of machine learning methods with a long history. Deep learning models are neural networks of many layers, which can extract multiple levels of features from raw data. Deep learning applied to healthcare is a natural and promising direction with many initial successes. The authors cover deep neural networks, convolutional neural networks, recurrent neural networks, embedding methods, autoencoders, attention models, graph neural networks, memory networks, and generative models. It’s presented with concrete healthcare case studies such as clinical predictive modeling, readmission prediction, phenotyping, x-ray classification, ECG diagnosis, sleep monitoring, automatic diagnosis coding from clinical notes, automatic deidentification, medication recommendation, drug discovery (drug property prediction and molecule generation), and clinical trial matching. This textbook targets graduate-level students focused on deep learning methods and their healthcare applications. It can be used for the concepts of deep learning and its applications as well. Researchers working in this field will also find this book to be extremely useful and valuable for their research.

Interest in machine learning is exploding worldwide, both in research and for industrial applications. Machine learning is fast becoming a fundamental part of everyday life. This book is a brief introduction to this area - exploring its importance in a range of many disciplines, from science to engineering, and even its broader impact on our society. The book is written in a style that strikes a balance between brevity of explanation, rigorous mathematical argument, and outlines principle ideas. At the same time, it provides a comprehensive overview of a variety of methods and their application within this field. This includes an introduction to Bayesian approaches to modeling, as well as deep learning. Writing small programs to apply machine learning techniques is made easy by high level programming systems, and this book shows examples in Python with the machine learning libraries 'sklearn' and 'Keras'. The first four chapters concentrate on the practical side of applying machine learning techniques. The following four chapters discuss more fundamental concepts that includes their formulation in a probabilistic context. This is followed by two more chapters on advanced models, that of recurrent neural networks and that of reinforcement learning. The book closes with a brief discussion on the impact of machine learning and AI on our society. Fundamentals of Machine Learning provides a brief and accessible introduction to this rapidly growing field, one that will appeal to students and researchers across computer science and computational neuroscience, as well as the broader cognitive sciences.

This book discusses the applications, challenges, and future trends of machine learning in medical domain, including both basic and advanced topics. The book presents how machine learning is helpful in smooth conduction of administrative processes in hospitals, in treating infectious diseases, and in personalized medical treatments. The authors show how machine learning can also help make fast and more accurate disease diagnoses, easily identify patients, help in new types of therapies or treatments, model small-molecule drugs in pharmaceutical sector, and help with innovations via integrated technologies such as artificial intelligence as well as deep learning. The authors show how machine learning also improves the physician’s and doctor’s medical capabilities to better diagnosis their patients. This book illustrates advanced, innovative techniques, frameworks, concepts, and methodologies of machine learning that will enhance the efficiency and effectiveness of the healthcare system. Provides researchers in machine and deep learning with a conceptual understanding of various methodologies of implementing the technologies in medical areas; Discusses the role machine learning and IoT play into locating different virus and diseases across the globe, such as COVID-19, Ebola, and cervical cancer; Includes fundamentals and advances in machine learning in the medical field, supported by significant case studies and practical applications.

The application of machine learning is growing exponentially into every branch of business and science, including medical science. This book presents the integration of machine learning (ML) and deep learning (DL) algorithms that can be applied in the healthcare sector to reduce the time required by doctors, radiologists, and other medical professionals for analyzing, predicting, and diagnosing the conditions with accurate results. The book offers important key aspects in the development and implementation of ML and DL approaches toward developing prediction tools and models and improving medical diagnosis. The contributors explore the recent trends, innovations, challenges, and solutions, as well as case studies of the applications of ML and DL in intelligent system-based disease diagnosis. The chapters also highlight the basics and the need for applying mathematical aspects with reference to the development of new medical models. Authors also explore ML and DL in relation to artificial intelligence (AI) prediction tools, the discovery of drugs, neuroscience, diagnosis in multiple imaging modalities, and pattern recognition approaches to functional magnetic resonance imaging images. This book is for students and researchers of computer science and engineering, electronics and communication engineering, and information technology; for biomedical engineering researchers, academicians, and educators; and for students and professionals in other areas of the healthcare sector. Presents key aspects in the development and the implementation of ML and DL approaches toward developing prediction tools, models, and improving medical diagnosis Discusses the recent trends, innovations, challenges, solutions, and applications of intelligent system-based disease diagnosis Examines DL theories, models, and tools to enhance health information systems Explores ML and DL in relation to AI prediction tools, discovery of drugs, neuroscience, and diagnosis in multiple imaging modalities Dr. K. Gayathri Devi is a Professor at the Department of Electronics and Communication Engineering, Dr. N.G.P Institute of Technology, Tamil Nadu, India. Dr. Kishore Balasubramanian is an Assistant Professor (Senior Scale) at the Department of EEE at Dr. Mahalingam College of Engineering & Technology, Tamil Nadu, India. Dr. Le Anh Ngoc is a Director of Swinburne Innovation Space and Professor in Swinburne University of Technology (Vietnam).

Machine Learning and Deep Learning in Medical Data Analytics and Healthcare Applications introduces and explores a variety of schemes designed to empower, enhance, and represent multi-institutional and multi-disciplinary machine learning (ML) and deep learning (DL) research in healthcare paradigms. Serving as a unique compendium of existing and emerging ML/DL paradigms for the healthcare sector, this book demonstrates the depth, breadth, complexity, and diversity of this multi-disciplinary area. It provides a comprehensive overview of ML/DL algorithms and explores the related use cases in enterprises such as computer-aided medical diagnostics, drug discovery and development, medical imaging, automation, robotic surgery, electronic smart records creation, outbreak prediction, medical image analysis, and radiation treatments. This book aims to endow different communities with the innovative advances in theory, analytical results, case studies, numerical simulation, modeling, and computational structuring in the field of ML/DL models for healthcare applications. It will reveal different dimensions of ML/DL applications and will illustrate their use in the solution of assorted real-world biomedical and healthcare problems. Features: Covers the fundamentals of ML and DL in the context of healthcare applications Discusses various data collection approaches from various sources and how to use them in ML/DL models Integrates several aspects of AI-based computational intelligence such as ML and DL from diversified perspectives which describe recent research trends and advanced topics in the field Explores the current and future impacts of pandemics and risk mitigation in healthcare with advanced analytics Emphasizes feature selection as an important step in any accurate model simulation where ML/DL methods are used to help train the system and extract the positive solution implicitly This book is a valuable source of information for researchers, scientists, healthcare professionals, programmers, and graduate-level students interested in understanding the applications of ML/DL in healthcare scenarios. Dr. Om Prakash Jena is an Assistant Professor in the Department of Computer Science, Ravenshaw University, Cuttack, Odisha, India. Dr. Bharat Bhushan is an Assistant Professor of Department of Computer Science and Engineering (CSE) at the School of Engineering and Technology, Sharda University, Greater Noida, India. Dr. Utku Kose is an Associate Professor in Suleyman Demirel University, Turkey.

This book provides a comprehensive overview of deep learning (DL) in medical and healthcare applications, including the fundamentals and current advances in medical image analysis, state-of-the-art DL methods for medical image analysis and real-world, deep learning-based clinical computer-aided diagnosis systems. Deep learning (DL) is one of the key techniques of artificial intelligence (AI) and today plays an important role in numerous academic and industrial areas. DL involves using a neural network with many layers (deep structure) between input and output, and its main advantage of is that it can automatically learn data-driven, highly representative and hierarchical features and perform feature extraction and classification on one network. DL can be used to model or simulate an intelligent system or process using annotated training data. Recently, DL has become widely used in medical applications, such as anatomic modelling, tumour detection, disease classification, computer-aided diagnosis and surgical planning. This book is intended for computer science and engineering students and researchers, medical professionals and anyone interested using DL techniques.

Artificial intelligence (AI) and machine learning (ML) techniques play an important role in our daily lives by enhancing predictions and decision-making for the public in several fields such as financial services, real estate business, consumer goods, social media, etc. Despite several studies that have proved the efficacy of AI/ML tools in providing improved healthcare solutions, it has not gained the trust of health-care practitioners and medical scientists. This is due to poor reporting of the technology, variability in medical data, small datasets, and lack of standard guidelines for application of AI. Therefore, the development of new AI/ML tools for various domains of medicine is an ongoing field of research. Machine Learning in Healthcare: Fundamentals and Recent Applications discusses how to build various ML algorithms and how they can be applied to improve healthcare systems. Healthcare applications of AI are innumerable: medical data analysis, early detection and diagnosis of disease, providing objective-based evidence to reduce human errors, curtailing inter- and intra-observer errors, risk identification and interventions for healthcare management, real-time health monitoring, assisting clinicians and patients for selecting appropriate medications, and evaluating drug responses. Extensive demonstrations and discussion on the various principles of machine learning and its application in healthcare is provided, along with solved examples and exercises. This text is ideal for readers interested in machine learning without any background knowledge and looking to implement machine-learning models for healthcare systems.