Fungal Biology And Related Diseases

Visit the accompanying website from the author at www.blackwellpublishing.com/deacon. Fungal Biology is the fully updated new edition of this undergraduate text, covering all major areas of fungal biology and providing insights into many topical areas. Provides insights into many topical areas such as fungal ultrastructure and the mechanisms of fungal growth, important fungal metabolites and the molecular techniques used to study fungal populations. Focuses on the interactions of fungi that form the basis for developing biological control agents, with several commercial examples of the control of insect pests and plant diseases. Emphasises the functional biology of fungi, with examples from recent research. Includes a clear illustrative account of the features and significance of the main fungal groups.

This book explores the developments in important aspects of fungi related to the environment, industrial mycology, microbiology, biotechnology, and agriculture. It discusses at length both basic and applied aspects of fungi and provides up-to-date laboratory-based data. Of the estimated three million species of fungi on Earth, according to Hawksworth and coworkers, more than 100,000 have been described to date. Many fungi produce toxins, organic acids, antibiotics and other secondary metabolites, and are sources of useful biocatalysts such as cellulases, xylanases, proteases and pectinases, to mention a few. They can also cause diseases in animals as well as plants and many are able to break down complex organic molecules such as lignin and pollutants like xenobiotics, petroleum and polycyclic aromatic compounds. Current research on mushrooms focuses on their hypoglycemic, anti-cancer, anti-pathogenic and immunity-enhancing activities. This ready-reference resource on various aspects of fungi is intended for graduate and post-graduate students as well as researchers in life sciences, microbiology, botany, environmental sciences and biotechnology.

The importance of fungal infections in both human and animals has increased over the last few decades. This book presents an overview of the different categories of fungal infections that can be encountered in animals (including lower vertebrates) originating from environmental sources with or without transmission to humans. In addition, the endemic infections with indirect transmission from the environment, the zoophilic fungal pathogens with near-direct transmission, the zoonotic fungi that can be directly transmitted from animals to humans, mycotoxicoses and antifungal resistance in animals will also be discussed. This book includes case studies and reviews the current state of knowledge on the mechanism of fungal attraction, recognition, infection, extracellular hydrolytic enzymes and pathogenesis of nematophagous fungi. The book also covers diagnostics, fungal formulations, as well as prevention methods. It discusses strategies to access the fungal pathogen groups, metagenomic analyses, genomics, secretomics, metabolomics, proteomics and transcriptomics. In addition, pathogen description, understanding, distribution and recent research results are provided.

Fungi: Biology and Applications is a comprehensive, balanced introduction of the biology, biotechnological applications and medical significance of fungi. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi. Later chapters move on to include more detailed coverage of topics such as proteomics, bioinformatics, heterologous protein expression, medical mycology, anti-fungal drug development and function, fungal biotechnology and fungal pathogens of economically important plants. Carefully structured, each chapter contains self-assessment exercises with answers included at the end of the book to enhance student understanding. A comprehensive treatment of the medical and economic importance of fungi to everyday life Chapters include revision sections and problems to reinforce key concepts Invaluable for undergraduates taking a first course on fungal biology or mycology. also of interest to those working within the field looking for an up-to-date introduction.

Fungal growths affect both human and animal well-being. Many natural pathogens of laboratory animals alter host physiology, rendering the host unsuitable for experimental uses. While the number and prevalence of few pathogens have declined considerably, many still turn up in laboratory animals and represent unwanted variables in research. Investigators using laboratory animals in biomedical experimentation should be aware of the profound effects that many of these agents can have on research. What does the future hold regarding the natural pathogens of laboratory animals? The selection of an animal model must carefully address issues of the type of human disease to mimic, the parameters to follow, and the collection of the appropriate data to answer those questions being asked. Overall, animal models of fungal infection will continue to deepen our understanding of how these infections occur. This book provides a valuable source of information to biological and biomedical scientists and to clinical and doctoral researchers working in the area of fungal infections and diseases of laboratory animal species.

Mycology has an integral role to play in the development of the biotechnology and biomedical sectors. It has become a subject of increasing importance as new fungi and their associated biomolecules are identified. As this discipline comes to the forefront of research in these sectors, the requirement for a consolidation of available research approaches is required. The First Edition of this book has a few basic and applied protocols. With the Second Edition, this book provides consolidated information on recent developments and the most widely used mycological methods available in the fields of biochemistry, biotechnology and microbiology. The methods outlined offer clear and concise directions to the reader and covers both standard protocols and more applied mycological methods. This book provides useful information for undergraduates, post-graduates, and specialists and researchers studying fungal biology.

Fungal diseases have contributed to death and disability in humans, triggered global wildlife extinctions and population declines, devastated agricultural crops, and altered forest ecosystem dynamics. Despite the extensive influence of fungi on health and economic well-being, the threats posed by emerging fungal pathogens to life on Earth are often underappreciated and poorly understood. On December 14 and 15, 2010, the IOM's Forum on Microbial Threats hosted a public workshop to explore the scientific and policy dimensions associated with the causes and consequences of emerging fungal diseases.