Gynecologic Pathology Practical Issues And Updates An Issue Of Surgical Pathology Clinics

In this issue of Surgical Pathology Clinics, guest editor Dr. Carlos Parra-Herran brings his considerable expertise to the topic of Gynecologic and Obstetric Pathology. Top experts cover emerging topics in gynecologic pathology that are relevant to clinical practice, including information on classification, terminology, diagnostic criteria, and ancillary testing. This issues also includes a review of the pathologic findings in specimens from patients undergoing gender-affirming surgery. Contains 14 practice-oriented topics including placental pathology: integrating consensus recommendations into practice; gestational trophoblastic neoplasia: contemporary diagnostic approach; homologous recombination deficiency and BRCA testing in pelvic high-grade serous carcinoma; ovarian sex cord stromal tumors and their mimickers; and more. Provides in-depth clinical reviews on gynecologic and obstetric pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This book serves as a quick review or summary of major diagnostic challenges in gynecologic pathology and embraces a Q/A format by providing the desired diagnostic knowledge. It combines the diagnostic approach as it relates to morphology and the relevant ancillary tests which impact on clinical outcome or management. Each topic is written by subspecialty gynecological pathologists in the field in making this a valuable book for a broad spectrum of readers, particularly pathology trainees, junior pathologists and general practicing pathologists. These authors provide concise and accurate answers for a variety of common, yet challenging diagnostic scenarios that are relevant and frequently encountered in daily practice. The book walks readers through current topics, controversies and diagnostic dilemmas for common gynecologic diseases with morphologic features and key ancillary tests, richly illustrated with figures and tables. To reflex the current advances in diagnostic gynecological pathology, the topics are closely correlated with the updated disease classifications and diagnostic criteria, particularly those recognized by the World Health Organization. Practical Gynecologic Pathology provides a concise summary and review for some of the most difficult, prevailing and emerging concepts in gynecologic pathology.

This issue of the Surgical Pathology Clinics, edited by Drs. Blaise Clarke and Glenn McCluggage, focuses on Gynecologic Pathology. Topics covered in the issue include, but are not limited to: Gynecologic manifestations of the DICER1 syndrome; Prophylactic gynecologic specimens from hereditary cancer carriers; Lynch syndrome associated endometrial cancer; Peutz-jeghers syndrome associated gynecologic tumors; Gynecologic manifestations of less commonly encountered hereditary syndromes; and Clinical testing for hereditary predisposition.

In this issue of Surgical Pathology Clinics, guest editor Dr. Carlos Parra-Herran brings his considerable expertise to the topic of Gynecologic and Obstetric Pathology. Top experts cover emerging topics in gynecologic pathology that are relevant to clinical practice, including information on classification, terminology, diagnostic criteria, and ancillary testing. This issues also includes a review of the pathologic findings in specimens from patients undergoing gender-affirming surgery. Contains 14 practice-oriented topics including placental pathology: integrating consensus recommendations into practice; gestational trophoblastic neoplasia: contemporary diagnostic approach; homologous recombination deficiency and BRCA testing in pelvic high-grade serous carcinoma; ovarian sex cord stromal tumors and their mimickers; and more. Provides in-depth clinical reviews on gynecologic and obstetric pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Zusammenfassung: Challenging Cases in Gynecologic Surgical Pathology discusses unusual clinical cases and uncommon presentations of usual diagnostic entities. The book is divided into four sections that contain over 14 years of teaching material from major academic institutions and cancer centers. The pathology case presentations are from different anatomical sites of the gynecological tract, including ovary and fallopian tubes, uterine corpus, cervix, and vulva. The chapters within each section contain epithelial, mesenchymal, or germ cell tumors and mimickers of cancer. Each case title has a brief clinical correlation at the end. The sample cases therein may be diagnostically challenging for practicing pathologists in routine practice or relatively recently described entities. The intent of the book is not a complete review of gynecologic pathology. Instead, the focus is on unusual patterns of common gynecologic pathology cases and uncommon tumors of the gynecological tract with their relevant clinical work-up and differential diagnosis. The case illustrations provide a practical approach to diagnosing challenging gynecologic cancers. The aim is to be a valuable resource for practicing general pathologists and pathology trainees who encounter complicated cases in daily practice

This issue of Surgical Pathology Clinics, Guest Edited by Dr. Brooke Howitt, will focus on practical issues and updates around Gynecologic Pathology. This issue is one of four selected each year by the series Consulting Editor, Jason L. Hornick. Topics include, but are not limited to, Non-HPV associated squamous neoplasia of the vulva and vagina; HPV-associated squamous neoplasia of the lower female genital tract; Cervical glandular neoplasia: classification and staging; Preinvasive lesions of the endometrium; Endometrial carcinoma: Grossing, frozen section evaluation, staging, and senitnel lymph node evaluation; High grade endometrial carcinomas: Classification with molecular insights; Uterine mesenchymal tumors: Classification, staging, and updates in molecular testing; Smooth muscle neoplasia of the female genital tract; Germ cell tumors of the female genital tract; Fallopian tube neoplasia and mimics; Low grade serous neoplasia of the female genital tract; Ovarian high grade serous carcinoma: Staging, assessing site of origin and the post-neoadjuvant chemotherapy setting; Ovarian mucinous tumors; Endometrioid and clear cell tumors of the ovary; and Ovarian sex cord stromal tumors.

This issue of Surgical Pathology Clinics, guest edited by Dr. Elizabeth G. Demicco, focuses on Soft Tissue Pathology. Topics include, but are not limited to, Prognostic and therapeutic biomarkers in sarcoma, Mesenchymal tumors with SMARC deficiency, Mesenchymal tumors with EWSR1-rearrangements, Update on fatty tumors, Pleomorphic sarcomas, Update on peripheral nerve sheath tumors, Beyond leiomyosarcoma - other mesenchymal tumors of the gynecologic tract, Non-Ewing small round cell tumors, Update on myogenic sarcomas, Radiation-associated Sarcomas, Practical application of cytology, and Update on molecular diagnostics in vascular tumors.

This new series for surgical pathologists presents "current concepts" in pathology diagnosis, key features, differential diagnosis, overview, pitfalls, and molecular approaches for every disease entity and body region. This publication on gynecologic epithelial tumors includes topics on Clinical approach to diagnosis and management of tumors of the cervis and vulva; Biomarkers in cervical cancer diagnosis; Pathology of vulvar neoplasms; Clinical approach to diagnosis and management of the corpus; Molecular overview of cancer of the corpus; Complex atypical hyperplasia and differentiated endometrioid adenocarcinoma; High-grade endometrial carcinoma; Familial tumors of the corpus; Clinical approach to diagnosis and management of the ovary, fallopian tube, and peritoneum; Molecular overview of cancers of the ovary, fallopian tube, and peritoneum; Metastatic carcinomas to ovary; Low-grade serous tumors; High-grade serous carcinoma; Non-serous ovarian epithelial tumors; and Familial tumors of the corpus.