Handbook Of Cell And Gene Therapy
Download Handbook Of Cell And Gene Therapy full books in PDF, epub, and Kindle. Read online free Handbook Of Cell And Gene Therapy ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Handbook of Cell and Gene Therapy
Author | : Hazel Aranha,Humberto Vega-Mercado |
Publsiher | : CRC Press |
Total Pages | : 444 |
Release | : 2023-03-17 |
Genre | : Science |
ISBN | : 9781000864250 |
Download Handbook of Cell and Gene Therapy Book in PDF, Epub and Kindle
This handbook provides an in-depth review of information across the developmental spectrum of gene and cell therapy products. From introductory information to state-of-the-art technologies and concepts, the book provides insights into upstream processes such as vector design and construction, purification, formulation and fill/finish, as well as delivery options. Planning steps for compliance with current good manufacturing practice (cGMP) to readiness for chemistry, manufacturing and controls (CMC) are also discussed. This book wraps up with examples of successes and pitfalls addressed by experts who have navigated the multiple challenges that are part of any innovative endeavor. Features Provides the most up-to-date information on the development of gene therapy, from the technology involved to gene correction and genome editing Discusses siRNA, mRNA, and plasmid manufacturing Describes the importance of supplier-sponsor synergies on the path to commercialization Written for a diverse audience with a large number of individuals in the core technologies and supportive practices It is intended as a one-stop resource for the availability of state-of-the-art information related to cell and gene therapy products for researchers, scientists, management and other academic and research institutions.
A Handbook of Gene and Cell Therapy
Author | : Clévio Nóbrega,Liliana Mendonça,Carlos A. Matos |
Publsiher | : Springer Nature |
Total Pages | : 195 |
Release | : 2020-06-27 |
Genre | : Medical |
ISBN | : 9783030413330 |
Download A Handbook of Gene and Cell Therapy Book in PDF, Epub and Kindle
This is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.
Gene Therapy
Author | : Kenneth W. Culver |
Publsiher | : Mary Ann Liebert |
Total Pages | : 144 |
Release | : 1994 |
Genre | : Medical |
ISBN | : UOM:39015032312368 |
Download Gene Therapy Book in PDF, Epub and Kindle
Stem Cells Handbook
Author | : Stewart Sell |
Publsiher | : Springer Science & Business Media |
Total Pages | : 498 |
Release | : 2003-10-22 |
Genre | : Medical |
ISBN | : 9781592594115 |
Download Stem Cells Handbook Book in PDF, Epub and Kindle
The power of stem cells for tissue development, regeneration, and renewal has been well known by embryologists and developmental biologists for many years. Those presently active in research in the stem cell field owe much to previous work by embryologists and cancer researchers for their insights into what stem cells can do. In the last 4- 5 years, the rapid expansion of the concept of adult tissue stem cells as pluripotent progenitors for various tissues has led to an even greater appreciation of the power of stem cells. The demonstration that both embryonic and adult tissue stem cells have the ability to produce progenitor cells for tissue renewal has opened vast possibilities for treatment of congenital deficiency diseases as well as for regeneration of damaged tissues. Older concepts of determination leading to loss of potential during differentiation of adult tissues are being replaced by newer ideas that cells with multiple potential exist in different forms in various adult organs and that cells thought to be restricted to differentiation to one cell type may be able to "transdifferentiate" into other tissue cell types. Thus, the concept of "embryonic rests" in adult tissues, hypothesized to be the cellular origin of cancer by Durante and Conheim in the 1870s, now can be expanded to include survival of pluripotential embryonic-like stem cells in adult tissues.
Handbook of Stem Cell Therapy
Author | : Khawaja Husnain Haider |
Publsiher | : Springer Nature |
Total Pages | : 1527 |
Release | : 2022-11-07 |
Genre | : Science |
ISBN | : 9789811926556 |
Download Handbook of Stem Cell Therapy Book in PDF, Epub and Kindle
The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell secretome-based cell-free strategies in regenerative medicine. The chapters in section I and section II respectively discuss the diverse applications of mesenchymal stem cells and non- mesenchymal stem cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapters in section IIIprimarily focused on the fast-emerging cell-free therapy approach in regenerative medicine for tissue repair and regeneration. These chapters review the impact of stem cell-derived secretome on various biological processes such as angiogenesis, neurogenesis, tissue repair, immunomodulation, musculoskeletal pathologies, wound healing, anti-fibrotic, and anti-tumorigenesis for tissue maintenance and regeneration.Lastly, section IV summarizes miscellaneous aspects of cell-based therapy, includingthe treatment advantages, opportunities, and shortcomings in stem cell-based therapy, potentially helping to refine future studies and translate them from experimental to clinical studies. Moreover, this section also has chapters on cancer stem cells as novel targets in cancer therapeutics. This Major Reference Book (MRW) is a valuable resource for researchers involved in stem cell research to understand the multifaceted therapeutic applications of stem cells and their derivative secretome in regenerative medicine.
A Guide to Human Gene Therapy
Author | : Anonim |
Publsiher | : Unknown |
Total Pages | : 135 |
Release | : 2024 |
Genre | : Electronic Book |
ISBN | : 9789814467100 |
Download A Guide to Human Gene Therapy Book in PDF, Epub and Kindle
An Introduction to Molecular Medicine and Gene Therapy
Author | : Thomas F. Kresina |
Publsiher | : John Wiley & Sons |
Total Pages | : 408 |
Release | : 2004-03-24 |
Genre | : Science |
ISBN | : 9780471461043 |
Download An Introduction to Molecular Medicine and Gene Therapy Book in PDF, Epub and Kindle
An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
Gene Therapy
Author | : Nancy Smyth Templeton,D. D. Lasic |
Publsiher | : CRC Press |
Total Pages | : 616 |
Release | : 2000-06-15 |
Genre | : Medical |
ISBN | : UOM:39015050321036 |
Download Gene Therapy Book in PDF, Epub and Kindle
This text covers all aspects of gene therapy, including basic principles, viral and nonviral delivery systems, targeted diseases, regulatory issues, and FDA requirements. It investigates genetic bullets to block HIV-1 replication and genetic guns to deliver antiviral agents.