Handbook Of Solubility Data For Pharmaceuticals
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Handbook of Solubility Data for Pharmaceuticals
Author | : Abolghasem Jouyban |
Publsiher | : CRC Press |
Total Pages | : 554 |
Release | : 2009-08-26 |
Genre | : Medical |
ISBN | : 9781439804889 |
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Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive datab
Handbook of Aqueous Solubility Data
Author | : Samuel H. Yalkowsky |
Publsiher | : CRC Press |
Total Pages | : 1513 |
Release | : 2003-03-26 |
Genre | : Medical |
ISBN | : 9780203490396 |
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Over the years researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until now, this information has been scattered throughout the literature. Containing over 16,000 solubility data points for more than 4,000 organic compounds, Handbook of Aqueous
Handbook of Aqueous Solubility Data
Author | : Samuel H. Yalkowsky,Yan He,Parijat Jain |
Publsiher | : CRC Press |
Total Pages | : 1622 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 9781439802465 |
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Over the years, researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until the first publication of the Handbook of Aqueous Solubility Data, this information had been scattered throughout numerous sources. Now newly revised, the second edition of
Solubility in Pharmaceutical Chemistry
Author | : Christoph Saal,Anita Nair |
Publsiher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 418 |
Release | : 2020-01-20 |
Genre | : Medical |
ISBN | : 9783110558883 |
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This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book.
Predicting Solubility of New Drugs
Author | : Alex Avdeef |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 2024 |
Genre | : Drug development |
ISBN | : 1032625252 |
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"In pharmaceutical research, solubility plays a key part in the assessment of pharmacokinetic risks. Poor drug absorption, reduced efficacy, excessive metabolism and adverse reactions are frequently related to issues of drug solubility. During early discovery research at pharmaceutical companies, many thousands of molecules are considered. Most are rejected due to perceived unfavorable properties. Here the author uses the so-called Wiki-pS0TM database which forms the backbone of this unique handbook. Also discussed is the emerging class of therapeutically-promising research molecules called PROTACs (proteolysis-targeting chimeras), showing a propensity for 'undruggable' targets"--
Handbook of Dissolution Testing
![Handbook of Dissolution Testing](https://youbookinc.com/wp-content/uploads/2024/06/cover.jpg)
Author | : William A. Hanson |
Publsiher | : Unknown |
Total Pages | : 159 |
Release | : 1991 |
Genre | : Medical |
ISBN | : 094333022X |
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Dissolution testing is used in the pharmaceutical industry to determine a drug's bioavailability and the bioequivalence of two drugs. Hanson details the techniques used, and provides guidelines for starting and operating a program. First published "nearly ten years ago." Available from Aster Publishing Corporation, 859 Willamette Street, Eugene OR 97440. Annotation copyrighted by Book News, Inc., Portland, OR
Handbook of Pharmaceutical Controlled Release Technology
Author | : Donald L. Wise |
Publsiher | : CRC Press |
Total Pages | : 908 |
Release | : 2000-08-24 |
Genre | : Medical |
ISBN | : 0824703693 |
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The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems. Contains cutting-edge research on the controlled delivery of biomolecules! Discussing the advantages and limitations of controlled release systems, the Handbook of Pharmaceutical Controlled Release Technology covers oral, transdermal, parenteral, and implantable delivery of drugs discusses modification methods to achieve desired release kinetics highlights constraints of system design for practical clinical application analyzes diffusion equations and mathematical modeling considers environmental acceptance and tissue compatibility of biopolymeric systems for biologically active agents evaluates polymers as drug delivery carriers describes peptide, protein, micro-, and nanoparticulate release systems examines the cost, comfort, disease control, side effects, and patient compliance of numerous delivery systems and devices and more!
Chemical Stability of Pharmaceuticals
Author | : Kenneth A. Connors,Gordon L. Amidon,Valentino J. Stella |
Publsiher | : John Wiley & Sons |
Total Pages | : 884 |
Release | : 1986-10-13 |
Genre | : Medical |
ISBN | : 047187955X |
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Provides a sound theoretical basis for understanding chemical kinetics and its uses in studying drug stability. Treats the calculations, approximations, and estimates that are useful to the pharmacist in professional practice, and presents a collection of selected drug-stability data from the pharmaceutical literature. This Handbook makes accessible to the pharmacist much of the information necessary to make pharmaceutical decisions about drug stability. Changes in this edition include thorough revision of the chapter on oxidation, addition of a new chapter on solid-state stability, and a tripling of the number of stability monographs. All monographs figures have been redrawn, most of them from published data, and all sources are cited.