Histological Typing Of Cancer And Precancer Of The Oral Mucosa

This book includes more clinical aspects and concentrates on cancer and precancer of the oral mucosa rather than attempting to cover all benign and malignant tumours of the oral and oropharyngeal tissue. One main emphasis is the significance of the clinical features of the various lesions discussed. Attention is also drawn to those conditions particular to the oral mucosa that may give rise to appearances which are important in differential diagnoses but can be misleading to those who do not have detailed knowledge of the tissue involved. The TNM-classification for malignant tumours of the lip and oral cavity is also included.

Oral squamous cell carcinoma (SCC) is the 13th commonest cancer worldwide, and the most common cancer in the Asian subcontinent due to the widespread habit of tobacco and betel nut chewing. Despite many advances in diagnosis and treatment, the survival statistics have only marginally improved. However our understanding of the disease process and transformation from pre-cancerous lesions of the oral mucosa to an invasive SCC cancer and their progression has expanded exponentially. There are many conditions of the oral mucosa that can progress to an invasive malignancy. A thorough understanding of these conditions is a prerequisite for all those involved in the management of the diseases of the oral mucosa and head and neck region. The recognition and timely treatment of potentially pre-malignant conditions of the oral cavity can minimize the change to an overt malignancy in many patients through patient education, appropriate treatment and surveillance. In this book we cover relevant anatomy, biology, diagnosis and latest management strategies for pre-cancerous conditions that affect the oral mucosa. The respective chapters are written by expert contributors from around the world, lending the book a global perspective and making it an essential guide for all those involved in the management of pre-malignant lesions arising in this challenging anatomical region.

Oral cancer is the sixth most common cancer worldwide. This authoritative international text unites the experience of specialists from both sides of the Atlantic and comprehensively addresses all aspects of the biology, etiology and pathology or oral cancer as well as clinical assessment, surgery, adjuvant therapies and post-treatment rehabilitation of the oral cancer patient. With over 550 illustrations, the majority of which are in full color, this book is a valuable and essential resource for any specialist working in the field of oral cancer.

Oral cancer as become one of the sixth most common cancer worldwide and also represents about 5.5% of all malignancies. In the Western world it is less common, but the incidence is increasing and the mortality rate has not improved for decades. Although most oral cancers probably arise in clinically normal mucosa some are preceded by a precancerous lesion which indicates an increased risk of cancer development at a particular site. The histopathologist's role is to recognize pathological features which indicate high risk and to provide prognostic information from examination of excised tumours. The most common precancerous lesion is a white patch on the oral mucosa referred to as a leukoplakia. These show variable clinical features ranging from relatively innocuous flat white plaques to verruciform or red and white speckled lesions. A proportion of' precancerous lesions show features of cytological atypia which are usually graded as mild, moderate or severe. The degree of epithelial dysplasia is a useful guide for the management of such lesions. In this book we cover relevant anatomy, biology, diagnosis and latest management strategies for pre-cancerous conditions that affect the oral mucosa. The respective chapters are written by expert contributors from around the world, lending the book a global perspective and making it an essential guide for all those involved in the management of pre-malignant lesions arising in this challenging anatomical region.