Histological Typing Of Thyroid Tumours

In Collaboration with Pathologists in 8 Countries

This book documents the most important clinicopathological features of rare thyroid tumours with an emphasis (and ample documentation) on their histological and immunohistochemical aspects. Whenever necessary, namely for differential diagnosis and/or therapy purposes, molecular data are also highlighted. In order to understand the histogenesis of rare lesions and to be able to make a differential diagnosis, the editors use the WHO book for endocrine tumours (in preparation) as a framework for classifying thyroid tumours. In addition to characterizing the main histotypes of thyroid tumours, this book also provides detailed information on how to approach the diagnosis of tumours according to the major morphological/immunohistochemical characteristics, the predominant morphology and whether or not they are hereditary. This book is a valuable learning tool for those involved in the differential diagnosis of thyroid lesions.

The classification represents an effort to bring together the variety of ways thymic epithelial neoplasms have been classified. It focuses on their growth characteristics, i.e. encapsulation and invasion, and cytoarchitectural features, e.g. spindle, epithelioid, and lymphocyte content. The classification, though restricted to the thymic region rather than the mediastinum in general, also covers neuroendocrine, germ cell, lymphoid, and stromal tumours, as well as tumour-like lesions and the neck tumours of thymic or related branchial pouch derivation.

Leonard Wartofsky, MD, past president of the American Thyroid Association, and a panel of world-class clinicians critically review all aspects of thyroid cancer from pathogenesis to prognosis, including management and treatment. Organized for rapid access by busy physicians, the book covers both differentiated tumors (papillary carcinoma and follicular carcinoma) and undifferentiated cancers (anaplastic carcinoma, lymphoma, and medullary carcinoma), as well as miscellaneous and unusual cancers of the thyroid. For each tumor type the authors succinctly discuss the key aspects of their clinical presentation, cytology, diagnosis, nuclear isotope scanning evaluation, imaging by MRI or CT, monitoring, surgery, pathology, post-operative care, and prognosis. Authoritative and evidenced-based, Thyroid Cancer: A Comprehensive Guide to Clinical Management provides in one place everything that physicians treating thyroid cancer patients need to know.