Horizontal Gene Transfer In The Evolution Of Pathogenesis
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Horizontal Gene Transfer in the Evolution of Pathogenesis
Author | : Michael Hensel,Herbert Schmidt |
Publsiher | : Cambridge University Press |
Total Pages | : 335 |
Release | : 2008-06-30 |
Genre | : Science |
ISBN | : 9781139472050 |
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Horizontal gene transfer is a major driving force in the evolution of many bacterial pathogens. The development of high-throughput sequencing tools and more sophisticated genomic and proteomic techniques in recent years has resulted in a better understanding of this phenomenon. Written by leading experts in the field, this edited volume is aimed at graduate students and researchers and provides an overview of current knowledge relating to the evolution of microbial pathogenicity. This volume provides an overview of the mechanisms and biological consequences of the genome rearrangements resulting from horizontal gene transfer, in both prokaryotes and eukaryotes, as well as overviews of the key mobile genetic elements involved. Subsequent chapters focus on paradigms for the evolution of important bacterial pathogens, including Salmonella enterica, Streptococcus pneumoniae, and Staphylococcus aureus. The influence of socioeconomic parameters in the dissemination of transferable elements, such as antibiotic resistant genes in bacteria, is also discussed.
Horizontal Gene Transfer in the Evolution of Pathogenesis
![Horizontal Gene Transfer in the Evolution of Pathogenesis](https://youbookinc.com/wp-content/uploads/2024/06/cover.jpg)
Author | : Michael Hensel,Herbert Schmidt |
Publsiher | : Unknown |
Total Pages | : 349 |
Release | : 2008 |
Genre | : Bacterial diseases |
ISBN | : 0511409273 |
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Horizontal Gene Transfer in the Evolution of Pathogenesis
![Horizontal Gene Transfer in the Evolution of Pathogenesis](https://youbookinc.com/wp-content/uploads/2024/06/cover.jpg)
Author | : Schmidt Herbert Hensel Michael |
Publsiher | : Unknown |
Total Pages | : 369 |
Release | : 2014-05-14 |
Genre | : Medical |
ISBN | : 0511409818 |
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Inferring Phylogenies
Author | : Joseph Felsenstein |
Publsiher | : Sinauer Associates Incorporated |
Total Pages | : 664 |
Release | : 2004-01 |
Genre | : Science |
ISBN | : 0878931775 |
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Phylogenies, or evolutionary trees, are the basic structures necessary to think about and analyze differences between species. Statistical, computational, and algorithmic work in this field has been ongoing for four decades now, and there have been great advances in understanding. Yet no book has summarized this work. Inferring Phylogenies does just that in a single, compact volume. Phylogenies are inferred with various kinds of data. This book concentrates on some of the central ones: discretely coded characters, molecular sequences, gene frequencies, and quantitative traits. Also covered are restriction sites, RAPDs, and microsatellites.
Pathogenicity Islands and the Evolution of Pathogenic Microbes
Author | : J. Hacker,James Kaper |
Publsiher | : Springer Science & Business Media |
Total Pages | : 260 |
Release | : 2002-03-01 |
Genre | : Science |
ISBN | : 3540426817 |
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It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well due to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.
The Pangenome
Author | : Hervé Tettelin,Duccio Medini |
Publsiher | : Springer Nature |
Total Pages | : 311 |
Release | : 2020-04-30 |
Genre | : Science |
ISBN | : 9783030382810 |
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This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Bioinformatics for Beginners
Author | : Supratim Choudhuri |
Publsiher | : Elsevier |
Total Pages | : 238 |
Release | : 2014-05-09 |
Genre | : Medical |
ISBN | : 9780124105102 |
Download Bioinformatics for Beginners Book in PDF, Epub and Kindle
Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. Avoids non-essential coverage, yet fully describes the field for beginners Explains the molecular basis of evolution to place bioinformatic analysis in biological context Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools Contains over 100 figures that aid in concept discovery and illustration
Lateral DNA Transfer
Author | : Frederic Bushman |
Publsiher | : CSHL Press |
Total Pages | : 472 |
Release | : 2002 |
Genre | : Medical |
ISBN | : 0879696214 |
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This book is about mobile genes—the transfer of DNA between unrelated cells. It discusses the machinery of gene transfer and its wide-ranging biological and health consequences. Mobile DNA makes possible the development of antibiotic resistance in microbes, the conversion of harmless to pathogenic bacteria, and the triggering of cancerous growth in cells. It also contributes to human evolution. This well-illustrated volume contains an up-to-date account of a topic now seen as increasingly important, and will be invaluable for both working scientists and as a textbook for advanced courses.