Immunogenetics

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. Contains exclusive information about research on immunogenetics from around the globe Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner

Delineating fundamental concepts of contemporary immunogenetics, this reference/text examines specific immunogenetic systems in terms of molecular biochemistry and immunophysiology. Covers material in diverse fields, including infectious diseases, cell biology, virology, molecular genetics. Comprise

Immunogenetics is a 12-chapter book that begins with the elucidation of the major histocompatibility complex genes and their role in autoimmune and infectious diseases. Subsequent chapters explore the human major histocompatibility complex, including implications of their complement genes for linkage disequilibrium and disease associations. This book also describes the genetics of human immunoglobulins; T-cell clones; genes of the major histocompatibility complex of the mouse; and the generation, characterization, and use of monoclonal antibodies of murine and human origin. Specific diseases are also discussed; these include spondoarthritides, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and autoimmune thyroid disease. This book will be of beneficial value to specialists in infectious diseases, endocrinology, connective tissue diseases, and neurology, as well as to medical scientists in immunology and molecular biology.

Because genetic factors can impact immune responses, and immunogenetic associations serve as a predictor of disease development and as a biological indicator of disease progression, the study of immunogenetics is important to basic genetics and immunology, as well as to translational and individualized medicine.This book addresses a few but important issues on the subject of immunogenetics. First, it will review the role that human leukocyte antigen molecules play in the immune system and then take into consideration the effectiveness of Western blotting for the detection of immunologic proteins. The book will discuss studies on the immunogenetics of cancer and tuberculosis followed by implications for immunotherapy. Working separately, the book will also provide evidence that the application of immunogenetics has improved our understanding of brain and behavior disorders.

Clinical Applications of Immunogenetics: Immunogenetics: A Molecular and Clinical Overview, Volume II provides readers with an exclusive, updated overview of scientific knowledge, achievements and findings in the field of immunogenetics. In thirteen chapters, the book gives insights in new advancements and approaches in viral and autoimmune diseases. Specific chapters are dedicated to immunogenetic mechanisms in the treatment of immune disorders, cancer, neurological and neurodegenerative disorders. In addition, other chapters cover immunogenomics in precision medicine, clinical medicine and transplantation. Finally, a special chapter, COVID-19: A novel challenge to human immune-genetic machinery, updates on thoughts surrounding the pandemic. Contains exclusive information about global research on immunogenetics Provides a solid foundation to researchers wanting to work on immunogenetics and their application in different autoimmune, viral and infectious diseases Delivers information in a meticulous, attractive manner using pictures, illustrations and tables Gives insights into immunogenetics and its utility in therapeutics

Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex