Immunotherapies For Allergic Disease

Get a quick, expert overview of the use of current and novel immunotherapies for use in the management and treatment of allergic reactions and diseases. This concise resource by Dr. Linda Cox covers the full range of allergic disease, including aeroallergens, asthma, food allergies, atopic dermatitis, and stinging insects. With essential coverage of allergen immunotherapies in addition to key topics on emerging allergen-associated immunomodulators, this succinct, comprehensive reference consolidates today’s available information on this timely topic into a single convenient resource. Discusses timely topics such as food tolerance, allergy, and allergen unresponsiveness; biologics for COPD and pediatric asthma; and adherence and pharmacoeconomics. Summarizes practical guidelines and recommendations for use of immunotherapies in clinical practice. Provides insight into the background and history of immunotherapies as a treatment for allergic disease. Includes developments on the horizon, including alternative immunotherapy routes and modified allergens.

This fifth edition of the bestselling Allergens and Allergen Immunotherapy is now completely updated and revised to include subcutaneous, sublingual, and oral immunomodulator treatments of allergic disease. The redesigned book continues to provide comprehensive coverage of all types of allergens and allergen vaccines, giving clinicians the essential information they need to accurately make a diagnosis and offer the best possible treatments. The fifth edition contains many new and revised chapters—particularly in the fields of skin testing—and extensive updates to the sublingual and oral immunotherapy chapters. Key Features: Comprehensive – covers a vast range of allergens and allergen immunotherapies, providing all the necessary information in one volume Synoptic – supplies the essential information using figures and tables for instant access Up-to-date – includes the very latest information on subcutaneous, sublingual and oral allergen immunotherapies to offer the best possible treatments Reliable – provides basic information that all clinicians need to know about cross-reactivity among allergens and how it influences diagnosis and treatment, as well as the key information necessary to carry out any form of immunotherapy in a safe and effective manner Supplemental forms – contains template forms that can be used by the clinician in daily practice The fifth edition of this classic text continues to be an essential touchstone for any practitioner who conducts skin tests and prescribes subcutaneous, sublingual, and oral immunotherapies.

Enlarged to describe more than a decade of advances in the immunotherapy of allergic diseases and asthma, this Third Edition contains the most recent studies on the mechanisms, manufacture, and standardization of various allergen groups and their utilization in the treatment of allergic diseases-containing 8 new chapters detailing various pharmacoe

The incidence of allergies is increasing worldwide. Beside the well-established symptomatic treatments and subcutaneous immunotherapies, formerly known as de- or hyposensitization, a new form of treatment, local immunotherapy, has been developed in recent years. Local immunotherapy, though still controversially discussed, promises to be a curative, noninvasive, and easily applicable treatment for allergies. This volume summarizes the most current information on local immunotherapy compiled by internationally renowned specialists. In the methodology section, general aspects of local immunotherapy are presented including its history, allergen resorption and biodistribution, mechanisms of oral tolerance and practical experiences. The second section devoted to efficacy and safety presents findings from international placebo-controlled studies on nasal and sublingual immunotherapies with different allergens and for different allergic conditions including asthma and eczema. Possible side effects are also discussed. The concluding chapter critically evaluates the future prospects of this new method, pointing out still unresolved issues such as the exact immunological mechanisms, its long-term effects, or the standardization of dose and application intervals/duration. This state-of-the-art account will be of particular interest to scientists working in the field of allergy, clinical allergologists, pharmacists, and representatives from the pharmaceutical industry.

Researchers and clinicians relate their experience with immunotherapy using antigens, which has remained important throughout the enormous advances in immunology over the past 30 years. Among the topics are a historical perspective, outdoor and indoor allergens, venoms, the preparation and administr

This issue of Immunology and Allergy Clinics, guest edited by Drs. Linda S. Cox and Anna H. Nowak-Wegrzyn, is devoted to Aeroallergen and Food Immunotherapy. Articles in this issue include History of AIT and the future direction of CRD/molecular allergy; Mechanisms of aeroallergen allergen immunotherapy: SCIT and SLIT; Mechanisms underlying induction of tolerance to foods; Biomarkers for allergen immunotherapy; SCIT and SLIT; Novel delivery routes for allergy immunotherapy; Oral immunotherapy for food allergy; SLIT and EPIT for food allergy; The use of adjuvants for enhancing allergen immunotherapy efficacy; Allergen immunotherapy vaccine modification; Allergen immunotherapy outcome assessment in clinical trials and real life; Component resolved diagnosis: can it make specific AIT more specific?; Baked milk and egg diets for milk and egg allergy management; and Allergen immunotherapy practical considerations: adherence and strategies to improve.

Allergy and Allergen Immunotherapy: New Mechanisms and Strategies is a valuable and comprehensive book that covers allergy and causative allergens and provides diagnostic and therapeutic aspects as well. With chapters from internationally recognized experts in the field, the book provides a balanced approach to enumerating pollen allergens as well as allergy diagnosis and therapeutic management and safety assessment of genetically engineered food allergens. The book features a special section on allergic diseases and allergens from tropical countries, including such countries such as India, Sri Lanka, Iran, and South Korea, giving the book a global appeal. The book is broken in the following sections: Epidemiology, Pathophysiology, and Diagnosis of Allergy Aerobiology and Allergic Diseases Pollen Allergy in the Tropics and Temperate Regions Allergy in Children Food Allergy Evaluation Allergen Immunotherapy and Anti IgE The book deals not only on basics of allergy and allergen immunotherapy but also discusses indoor environments and safety considerations of genetically modified food allergens. The first of its kind volume from the Indian subcontinent that caters to the needs of clinicians, aerobiologists, environmentalists, and regulatory agencies as well, the volume will be of immense interest for clinicians and patients of allergy as well as diagnostic and therapeutic management of allergy in tropics.

Enlarged to describe more than a decade of advances in the immunotherapy of allergic diseases and asthma, this Third Edition contains the most recent studies on the mechanisms, manufacture, and standardization of various allergen groups and their utilization in the treatment of allergic diseases-containing 8 new chapters detailing various pharmacoeconomic, regulatory, manufacturing, administration, and safety issues concerning new and emerging immunotherapy techniques.