Inhaled Particles

Inhaled Particles integrates all that is known about inhaled particles in a unified treatment. It aims to provide a scientific framework essential to a reasonable understanding of inhaled particles. The emphasis is placed on demonstrating the key roles of lung morphology on airflow and particle transport as well as identifying physical and biological factors that influence deposition. Special attention is paid to maintaining consistency of treatment and a balance between theoretical modeling and experimental measurements. The book covers all important aspects of inhaled particles including inhalability, aerosol dispersion, particle deposition, and clearance. It reviews concisely the basic background of lung morphology, respiratory physiology, aerodynamics, and aerosol science pertinent to the subject. Essential aspects of health effects and applications are also included. An easy-to-read, self contained introduction to the field An excellent source of updated research information Useful for students and professionals in aerosol science, environmental health science, occupational hygiene, health physics and biomedical engineering

Inhaled Particles VI contains the proceedings of an international symposium and workshop on lung dosimetry, organized by the British Occupational Hygiene Society in cooperation with the Commission of the European Communities and held at Cambridge on September 2-6, 1985. The symposium presents results of research on the entry, destiny, and effects of respired particles, with emphasis on mechanisms and dose-response relationships. This book contains, in three separate parts, 84 papers from the symposium, 34 workshop papers, and 20 poster presentations. Parts 1 and 2 are further divided into sections. Section 1 presents several papers concerning the influence of breathing pattern and activity on regional deposition of inhaled particles. Section 2 shows comparative studies of aerosol deposition in experimental animals and humans. Subsequent sections explore the mineral content of lungs to differing exposures; biological effects of dusts; hazard parameters; dust measurement; exposure of workers to vermiculite and attapulgite; effects of dust exposure in the coal mining industry; and effects of silica dust exposure. Other topics of significance include toxicity of artificial mineral fibers and utility of magnetopneumography as a non-invasive investigational test.

Inhaled Particles and Vapors covers the proceedings of an International Symposium by the same title on September 28 – October 1, 1965, organized by the British Occupational Hygiene Society. This book is organized into seven sections encompassing 48 chapters. Section I reviews the anatomy and physiology of human lung. Section II describes the pulmonary response to dust in terms of airway changes and reactions to silica. Sections III and IV deal with lung clearance in animals, the retention, penetration, and elimination of inhaled dusts, and lung deposition and clearance in human. Section V emphasizes the sources of dust inhaled by the human lungs, while Section VI discusses the relationship between pneumonoconiosis and dust exposure. Section VII presents the results of the investigations of dust exposure. This book will prove useful to pulmonologists, toxicologists, and workers in the field of occupational health.

The Annals of Occupational Hygiene: Inhaled Particles V emphasizes respired particles, particularly their effects, fate, and entry, by considering quantitative exposure-effect relationships and basic mechanisms. Divided into eight sections, the book presents analysis of the dynamics of particles that enter the mouth or nose, which has been considered relative to hygiene standards grounded on ‘total dust’. The concerns include the retention of mineral fibers and asbestos in the lungs. The effects on health of coal dusts and fly ash generally common in the energy industries are considered. The text also presents the tests of the carcinogenicity and pathogenicity of dusts and the toxicity of nitrous oxides. The book then focuses on the response of the airways to aerosols, sulfates, gold mine dusts, and organic dusts. Coal mining and its relationship with the progression of pneumoconiosis are also discussed. The book is a great source of information for those who are doing studies in the field of occupational health, particularly on the effects of dust and other related particles on the health of workers.

This book assists scientists, toxicologists, clinicians, and public health regulators to understand the complex issues that determine the impact of air pollution on the cardiovascular system. It covers a range of relevant topics including particulate matter (PM) sources and characterization, methods of exposure, impact of PM on cells and systems, role of particles in the pathophysiology of cardiovascular disease, risk assessment, and potential environmental and therapeutic interventions.

Pulmonary Deposition and Retention of Inhaled Aerosols is concerned with the respiratory deposition and retention of inhaled aerosols, starting with initial intake and concluding with events that precede pathological tissue response, drawing equally upon both the physical and biological aspects of the subject. The book opens with an introductory chapter on the relationship between the dose of an inhaled aerosol and the kind and degree of response, and classification of particulate substances. This is followed by separate chapters on pulmonary deposition and retention of inhaled aerosols; the factors that influence disease risks associated with atmospheric exposure to aerosols; and measurement of aerosol composition and concentration. It is hoped that the book will help the specialists from both sides as well as technical and administrative personnel to acquire a common understanding of the important intermediate factors that operate between the outside dusty atmosphere and the internal tissue damage and disease—factors that may operate to make one exposure dangerous to life and another altogether innocuous.