Inorganic Controlled Release Technology

Inorganic Controlled Release Technology: Materials and Concepts for Advanced Drug Formulation provides a practical guide to the use and applications of inorganic controlled release technology (iCRT) for drug delivery and other healthcare applications, focusing on newly developed inorganic materials such as bioresorbable glasses and bioceramics. The use of these materials is introduced for a wide range of applications that cover inorganic drug delivery systems for new drug development and the reformulation of existing drugs. The book describes basic concepts, principles, and industrial practices by discussing materials chemistry, physics, nano/microstructure, formulation, materials processing, and case studies, as well as the evaluation and characterization of iCRT systems commonly investigated during industrial R&D. Provides the first book on inorganic controlled release technology (iCRT), covering key aspects from chemistry, physics, synthetic methods, formulation design, characterization and evaluation Includes several industry-related case studies to provide practical guidance on how to use iCRT as an alternative to organic polymers systems for both future drug developments and other active ingredient applications Demonstrates how iCRT offers an unmet business need for improved, controlled release of actives versus traditional CRT systems, which are known to have difficulty with the controlled delivery of both poorly and highly water soluble drug compounds

This book provides a practical guide to the use and applications of inorganic biomaterials. It begins by introducing the concept of inorganic biomaterials, which includes bioceramics and bioglass. This concept is further extended to hybrid biomaterials consisting of inorganic and organic materials to mimic natural biomaterials. The book goes on to provide the reader with information on biocompatibility, bioactivity and bioresorbability. The concept of the latter is important because of the increasing role resorbable biomaterials are playing in implant applications. The book also introduces a new concept on mechanical compatibility - 'mechacompatibility'. Almost all implant biomaterials employed to date, such as metal and ceramic implants, do not meet this biological requirement as they have far higher modulus than any biomaterials in the body. The practical techniques that are used in the characterization of biomaterials, including chemical, physical, biological, microscopy and mechanical characterization are described. Some specialised techniques are also introduced such as Synchrotron Micro-Computed Tomography (u-CT) and Magnetic Resonance Imaging (MRI). The reader is given important information on new biomaterials development for orthopaedic and other areas, including controlled release technology, hydroxyapatite and hybrid bioresorbable materials. Finally the book provides a guide to regulatory considerations, an area which is often overlooked, but is an important part of R&D and manufacturing of medical materials and devices.

Nanocellulose Materials: Fabrication and Industrial Applications focuses on the practices, distribution and applications of cellulose at the nanoscale. The book delivers recent advancements, highlights new perspectives and generic approaches on the rational use of nanocellulose, and includes sustainability advantages over conventional sources towards green and sustainable industrial developments. The topics and sub-topics are framed to cover all key features of cellulose, from extraction to technological evolution. Nanocellulose has great potential due to its versatility and numerous applications, including the potential role of nanocellulose scaffold derivatives towards active involvement in the energy sector, chemical sensing, catalysis, food industry and anti-bacterial coatings towards land, agricultural and aquatic systems. Explores the whole spectrum of industrial scale fabrications and the utilization of nanocellulose as a sustainable material or as part of a sustainability agenda Discusses the environmental, legal, health and safety issues of nanocellulose Assesses the major challenges and opportunities for using nanocellulose at an industrial scale

Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

Calcium-based natural minerals are important for a wide range of applications. Though these materials are available in nature, researchers are working toward developing them in the laboratory. Calcium-Based Materials: Processing, Characterization, and Applications introduces the possibility of designing these materials for particular applications. Introduces a variety of calcium-based materials and discusses synthesis, growth, and stability Provides in-depth coverage of calcium carbonate Discusses applications of calcium-based minerals in different fields Includes details on synchrotron X-ray tools for case minerals This comprehensive text is aimed at researchers in materials science, engineering, and bioengineering.

An authoritative summary of the quest for an environmentally sustainable synthesis process of nanomaterials and their application for environmental sustainability Green Synthesis of Nanomaterials for Bioenergy Applications is an important guide that provides information on the fabrication of nanomaterial and the application of low cost, green methods. The book also explores the impact on various existing bioenergy approaches. Throughout the book, the contributors—noted experts on the topic—offer a reliable summary of the quest for an environmentally sustainable synthesis process of nanomaterials and their application to the field of environmental sustainability. The green synthesis of nanoparticles process has been widely accepted as a promising technique that can be applied to a variety of fields. The green nanotechnology-based production processes to fabricate nanomaterials operates under green conditions without the intervention of toxic chemicals. The book’s exploration of more reliable and sustainable processes for the synthesis of nanomaterials, can lead to the commercial application of the economically viability of low-cost biofuels production. This important book: Summarizes the quest for an environmentally sustainable synthesis process of nanomaterials for their application to the field of environmental sustainability Offers an alternate, sustainable green energy approach that can be commercially implemented worldwide Covers recent approaches such as fabrication of nanomaterial that apply low cost, green methods and examines its impact on various existing bioenergy applications Written for researchers, academics and students of nanotechnology, nanosciences, bioenergy, material science, environmental sciences, and pollution control, Green Synthesis of Nanomaterials for Bioenergy Applications is a must-have guide that covers green synthesis and characterization of nanomaterials for cost effective bioenergy applications.

The explores the cutting-edge technology of polymer coatings. It discusses fundamentals, fabrication strategies, characterization techniques, and allied applications in fields such as corrosion, food, pharmaceutical, biomedical systems and electronics. It also discusses a few new innovative self-healing, antimicrobial and superhydrophobic polymer coatings. Current industrial applications and possible potential activities are also discussed.

Smart Textiles: Wearable Nanotechnology provides a comprehensive presentation of recent advancements in the area of smart nanotextiles giving specific importance to materials and production processes. Different materials, production routes, performance characteristics, application areas and functionalization mechanisms are covered. The book provides a guideline to students, researchers, academicians and technologists who seek novel solutions in the related area by including groundbreaking advancements in different aspects of the diverse smart nanotextiles fields. This ground-breaking book is expected to spark an inspiration to allow future progress in smart nanotextiles research. The diversity of the topics, as well as the expert subject-matter contributors from all over the world representing various disciplines, ensure comprehensiveness and a broad understanding of smart nanotextiles.