Integrity Of The Autonomic Nervous System In Psychiatric And Neurological Disorders

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The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

The second edition of this successful book provides further and in-depth insight into theoretical models dealing with Internet addiction, as well as includes new therapeutical approaches. The editors also broach the emerging topic of smartphone addiction. This book combines a scholarly introduction with state-of-the-art research in the characterization of Internet addiction. It is intended for a broad audience including scientists, students and practitioners. The first part of the book contains an introduction to Internet addiction and their pathogenesis. The second part of the book is dedicated to an in-depth review of neuroscientific findings which cover studies using a variety of biological techniques including brain imaging and molecular genetics. The third part of the book focuses on therapeutic interventions for Internet addiction. The fourth part of the present book is an extension to the first edition and deals with a new emerging potential disorder related to Internet addiction – smartphone addiction. Moreover, in this second edition of the book new content has been added. Among others, the reader will find an overview of theoretical models dealing with Internet addiction, results from twin studies in the context of Internet addiction and additional insights into therapeutic approaches to Internet addiction.

Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today’s systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout. Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation. The Nervous System provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases. Organization of the Nervous System Elements of Cellular and Molecular Neuroscience Clinical Assessment The Spinal Cord Pain and Analgesia Cranial Nerves and the Brainstem The Visual System Hearing and Balance: The Auditory and Vestibular Systems Motor Systems I: Descending Pathways and Cerebellum Motor Systems II: The Basal Ganglia Stroke and Head Injury Infection in the Central Nervous System Epilepsy Dementia Schizophrenia and Neurodevelopmental Disorders Depression and Anxiety Addiction Systems of the Body Series: The Renal System The Musculoskeletal System The Nervous System The Digestive System The Endocrine System The Respiratory System The Cardiovascular System

A comprehensive, systematic, and advanced review of the scientific, preclinical, and clinical aspects of several major mental illnesses. The illnesses covered range from neurological disorders including Alzheimer's disease, Huntington's disease, and Parkinson's disease, to psychiatric disorders including schizophrenia, autism spectrum disorders, Tourette's syndrome and tic disorders, obsessive-compulsive disorder, unipolar depression, bipolar disorder, and attention deficit hyperactivity disorder. For each disorder, the authors uniformly discuss its incidence and prevalence, etiology, molecular targets and mechanisms of action, brain structures and pathways, animal models, signs and symptoms, genetics, treatments, and related medical terminology.

There has been a rapid global increase in the number of individuals making sleep medicine their career, resulting in an explosive growth in the number of sleep centres and programmes, as well as an increasing number of sleep societies and journals. Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Sleep Disorders covers the rapid advances in scientific, technical, clinical, and therapeutic aspects of sleep medicine which have captivated sleep scientists and clinicians. This text aims to introduce sleep disorders within the context of classical neurological diseases, giving an in-depth coverage of the topic in a logical and orderly way, while emphasizing the practical aspects in a succinct and lucid manner. Divided into 12 sections, this book begins by discussing the basic science (Section 1), before moving onto the laboratory evaluation (Section 2) and the clinical science (Section 3). The remainder of the book focuses on specific sleep disorders (Sections 4-12), from insomnias and parasomnias to sleep neurology and sleep and psychiatric disorders. Chapters are supplemented by tables, case reports, and illustrations intended to succinctly provide relevant information in a practical manner for diagnosis and treatment of sleep disorders, while always emphasizing clinical-behavioural-laboratory correlations.

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.