Iron Metabolism In Infants

There is a critical need for iron intake during the first period of life. The growing infant requires iron to synthesize hemoglobin and to supply expanding tissues with iron-containing enzymes. A lack of iron will eventually lead to iron deficiency anemia, one of the most common single nutrient deficiencies in the world. Today, detailed information has increased our understanding of iron bioavailability from different dietary sources, uptake mechanisms of iron into the small intestinal mucosa for transport to hepatocytes and erythropoietic cells and subsequent receptor mediated cellular acquisition. Metabolic effects of iron deficiency have also been investigated in several tissues. This comprehensive text integrates recent information and address it from a nutritional perspective. It takes this focus because of the increased knowledge on the interrelationship between iron and other essential nutrients. Specific problems of iron nutriture and oxidant stress in prematurely born infants are also addressed in this informative new text

Abstract: Iron metabolism and the prevention, diagnosis, and treatment of iron deficiency during infancy and childhood are described. Iron deficiency constitutes the most common deficiency in both industrialized and developing nations. It is prevalent among infants and young children because their rapid growth imposes great needs for iron. Prolonged breast feeding and iron fortification are among the methods used to prevent the deficiency. Laboratory tests aimed at its diagnosis include measuring hemoglobin concentration and serum ferritin. Treatment usually involves the ingestion of ferrous sulfate.

This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.

Iron deficiency in infancy is very widespread, even in developed countries and even when there is no general malnutrition. This book examines the question whether iron deficiency in early life leads to deleterious changes in brain and/or behavioural development. Each of the nine contributors comments critically on each of the other eight chapters, so that the book is very extensively peer-reviewed. The evidence is set out so that the reader may make his own informed judgement. Iron deficiency could very easily be prevented; this fact is of prime importance if such deficiency has long-lasting effects on human intellectual capacity and achievement.

This guideline aims to help Member States and their partners in their efforts to make informed decisions on the appropriate nutrition actions to achieve the Sustainable Development Goals (SDGs) the global targets set in the Comprehensive implementation plan on maternal infant and young child nutrition and the Global Strategy for Women?s Children?s and Adolescents? Health 2016-2030. The recommendations in this guideline are intended for a wide audience including policy-makers their expert advisers and technical and programme staff at organizations involved in the design implementation and scaling-up of anaemia prevention programmes and in nutrition actions for public health.

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

This publication is a training resource that deals with the period prior to successful weaning when a child continues to receive breast milk but also needs increasing amounts of addtional complementary foods to ensure healthy development. It is intended as a practical learning tool for all those responsible for the health and nutrition of young children, particularly health and nutrition workers, and their trainers.

In Part I of Nutrition During Pregnancy, the authors call for revisions in recommended weight gains for pregnant women. They explore relationships between weight gain during pregnancy and a variety of factors (e.g., the mother's weight for height before pregnancy) and places this in the context of the health of the infant and the mother. They present specific target ranges for weight gain during pregnancy and guidelines for proper measurement. Part II addresses vitamin and mineral supplementation during pregnancy, examining the adequacy of diet in meeting nutrient needs during pregnancy and recommending specific amounts of supplements for special circumstances. It also covers the effects of caffeine, alcohol, cigarette, marijuana, and cocaine use and presents specific research recommendations.