Kirsner S Inflammatory Bowel Diseases

This comprehensive New Edition describes all of the latest scientific and clinical advances in the field of inflammatory bowel disease (IBD). A new editorial team-joined by a superb group of international authorities-examine every aspect of IBD-including etiology and pathogenesis, diagnosis and evaluation, medical and surgical therapy, and more. A wealth of expanded coverage, additional international contributors, extensive updating throughout, and numerous diagnostic and therapeutic algorithms make this an essential resource. Emphasizes evidence-based medicine in the section on medical therapy. Features a detailed description of inflammatory and immunologic pathways, allowing the reader to fully understand the contributing influences to the inflammation of IBD. Presents separate chapters on molecular genetics and clinical genetics for more in-depth coverage of each aspect of inflammatory bowel disease genetics. Provides a comprehensive review of IBD through abundant, high-quality endoscopic, radiographic, and histologic photographs-placing the various diagnostic modalities in perspective. Offers extensive coverage of postoperative recurrence of Crohn's disease · pouchitis · microscopic colitis · perianal disease · and osteoporosis. Includes up-to-the-minute guidance (including many 2003 references). Features a new editorial team, joined by numerous new contributors who provide fresh, global perspectives. Includes nine new chapters. Offers expanded coverage throughout, and through revisions of all pre-existing chapters. With over 75 additional contributing experts.

Few human illnesses today are so challenging, medically, scientifically, and socio-economically, as the "nonspecific" inflammatory bowel diseases (IBD): ulcerative colitis and Crohn's disease. Originating several centuries ago but essentially diseases of the 20th century, often attacking children and young adults, involving all bodily systems as well as the gastrointestinal tract, ulcerative colitis and Crohn's disease have emerged in recent decades as among the more "glamorous" unsolved diseases, presenting unusual opportunities for insightful clinical and investigative study. Many of the prevailing concepts originated during the early and mid 20th century. The purpose of Origins and Directions of Inflammatory Bowel Disease is to review these earlier studies and their evolution "from the mystical to the molecular," and guide investigators and physicians through the challenging clinical and scientific maze of IBD.

An international symposium on inflammatory bowel diseases was held in Jerusalem on September 7th-9th, 1981. The symposium was sponsored by the Hebrew University-Hadassah Medical SchooL and the Israeli Gastroenterological Society. The idea was to bring together leading workers in the field, to invite all those interested to present their new work on IBD and thus to enable exchange of information and cross fertilization needed to improve our understanding and handling of these diseases. The symposium was organized into four panels devoted to state of the art reviews. presentation of new findings and approaches on the follow ing topics: New pathological concepts. etiology. pathogenesis and management of IBD. In addition. 89 abstracts were presented as posters during the symposium. all of which were published in the book of abstracts. The concluding panel outlined new directions for future research on IBD. We owe our gratitude to Drs. J. B. Kirsner, G. L. Gitnick and C. E. Rubin, members of the Organizing Committee, without whose encouragement and help the symposium could not have taken place. The Organizing Committee owes a considerable debt of gratitude to all the contributors who presented their work in a clear and concise manner, to all those who presented posters and to all the participants who came from 27 countries. Their stimulating presentations and discussions con tributed to the success of the meeting.