Lecture Notes On Molecular Medicine

Lecture Notes on Molecular Medicine provides a concise and straightforward introduction to molecular biology, explaining how it is used to understand and treat human disease. This new edition has been written in response to exciting changes in this fast-moving field. Fully updated, it explains the human genome project and how the sequence will change medicine. It also covers many new methods that have been introduced since the first edition was published. Beginning with first principles, the book is a useful primer for any science student new to molecular biology and genetics. It is also an invaluable resource for medical students and practicing doctors who need an understanding of how advances in molecular biology have impacted clinical medicine, especially in the fields of gene therapy and screening. For ease of use Lecture Notes on Molecular Medicine is divided into four sections: Basic Principles: describing the fundamentals of DNA structure and function that underpin molecular biology Biomolecular Tools: covering the manipulation of DNA and RNA and molecular techniques. Understanding Genetics: covering the basic principles of inheritance, biodiversity, gene mapping and expression and gene therapy. Molecular Medicine in Practice: discussing the profound effect which molecular biology has had on medical practice at all levels. This chapter has been greatly expanded in this new edition to cover all the latest developments in the field. A concise introduction to the basic principles & applications of molecular medicine. Explains complicated science in simple terms with clear diagrams. Integrates basic and clinical science by emphasising application to clinical medicine. Expanded chapter examining molecular medicine in clinical practice.

Lecture Notes: Medical Genetics provides a concise and straightforward introduction to medical genetics. The text aims to give students a fundamental understanding of the science of genetics and molecular medicine and a knowledge of the core clinical conditions caused by genetic abnormalities. Previously titled Lecture Notes on Molecular Medicine, this new edition has a greater focus on clinical genetics while continuing to provide core information on the scientific background and advances in genetics and molecular medicine. Thoroughly revised and updated, Lecture Notes: Medical Genetics is an invaluable primer for any science student new to molecular biology and genetics, and an excellent resource for medical students, junior doctors and practicing clinicians requiring an understanding of scientific advances in the field and their impact on clinical medicine.

How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and find entry to the more specialized publications. The first chapters present the basic concepts of the human genome and gene regulation. Subsequent chapters consider how today's new approach can be applied in areas such as forensic medicine, transplantation medicine, drug manufacture and genetic engineering. For example, a major section on cancer explores the diagnosis of leukemia and lymphoma through the detection of gene rearrangement and oncongeny mutation. One feature that will especially interest pathologists, pediatricians and residents is the discussion of diagnostic tests that are used in current practice.

Cancer is one of the most exciting specialties in medicine. This book aspires to convey the authors’ enthusiasm for oncology and this new edition of Oncology Lecture Notes is a must for students and trainees. There has been a revolution in the practice of oncology. The changes are due to amazing advances in basic science, and the development of new drugs and successful immunisation programmes that have followed. Cancer death rates have fallen and this is in part due to radical new treatments, effective screening programmes, and also, as a result of popular movements for change in patient care, and decreased exposure to carcinogens. Completely revised and updated, this new edition of Oncology Lecture Notes describes advances in molecular biology research and highlights the importance of patient perspectives in cancer care. The text includes many new figures and tables, an update of molecular biology and highlights new treatments. With learning objectives and key point summaries in each chapter, Oncology Lecture Notes is an ideal introduction to the biological basis and principles of treatment in oncology. Includes a companion website at www.lecturenoteseries.com/oncology featuring cases and self-assessment MCQs

"This book should be useful to lecturers who teach senior undergraduates, graduate students, and students in the biomedical sciences in general. More globally, Greenwell and McCulley's book should encourage academicians of any stripe who for some time have been honing their lectures in a niche subject area to turn their courses into textbooks." –Biochemistry and Molecular Biology Education Molecular therapeutics refers to the developments in molecular biology that are focused on treating disease with new molecular-based drugs. By taking advantage of recent advances and increased understanding in the field of human genetics, this book provides essential background knowledge and key literature on a broad range of novel approaches and disciplines. These include making recombinant proteins, xenotransplantation gene therapy and therapeutic cloning. Molecular Therapeutics: 21st Century Medicine describes the techniques - including their associated benefits, problems, pitfalls - and discusses their applicability with respect to treating microbial, inherited, multifactoral and acquired diseases. The book also pays specific attention to the ethical issues associated with this new field. Cutting-edge topics and clinically relevant materials engage and maintain student interest Self-assessment questions are included throughout the book Features an additional web site, with a web forum, regular updates and PowerPoint slides of figures from the book Molecular Therapeutics: 21st Century Medicine is a comprehensive, accessible and engaging guide to the rapidly developing field of molecular therapeutics. It is essential reading for all students in this area of research and also of interest for health professionals involved in these novel therapies.