Lip Cancer

This textbook is intended as a comprehensive reference that will provide easy-to-follow and well-organized guidance on the management of lip cancer, from diagnosis to treatment and reconstruction. After discussion of anatomy and premalignant conditions, detailed attention is paid to squamous cell carcinoma of the lip. Surgical management is explained, and the roles of radiation therapy and chemotherapy, discussed. Reconstruction techniques following ablative surgery are then described in depth, with reference to defect size and complexity. In addition, the potential complications of treatment and reconstruction are presented, with advice on their management. The closing chapter considers other malignant lesions of the lip. The informative text is complemented by high-quality illustrations and clinical and radiographic material. The contributors all have extensive experience and in-depth knowledge of the topics they address.​

Management of Complications in Oral and Maxillofacial Surgery, 2nd Edition, presents clear and consistent guidance on all aspects of both common and less common, minor and major complications encountered in oral and maxillofacial surgery (OMS) practice. In-depth chapters provide thorough descriptions of each complication and recommend treatment strategies for associated complications of anesthesia, implant surgery, maxillofacial trauma, and more, using easy to read algorithms. Fully revised and expanded, the Second Edition incorporates the most current evidence and advances in the specialty, including implementation of virtual surgical planning for orthognathic and reconstructive surgery. Nine entirely new chapters address complications in minimally invasive cosmetic surgery, lip cancer, dermatopathology and skin cancer, microneurosurgery for trigeminal nerve injuries, transoral robotic surgery (TORS), sialoendoscopy complications, perioperative navigation for dental implants, head and neck radiotherapy, and ambulatory anesthesia in pediatric and geriatric patients. Highlights include: Provides a systematic, easy-to-read approach to complication prevention, recognition, and management Covers most potential complications, ranging from the routine to the complex Features more than 500 high-quality clinical images demonstrating all concepts discussed in the text Includes keywords, tables, learning objectives, and further readings in each chapter Includes treatment algorithms to guide clinical decision-making Edited by prominent oral and maxillofacial surgeons with contributions by leading experts in their respective areas Management of Complications in Oral and Maxillofacial Surgery, Second Edition is a must-have for all oral and maxillofacial surgeons, residents, and trainees, and a valuable resource for dental students and dental practitioners, for clinical practice, and for examination preparation.

This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

Oral cancer is a significant public health challenge globally. Although the oral cavity is easily accessible, early diagnosis remains slow compared to the enhanced detection of cancers of the breast, colon, prostate, and melanoma. As a result, the mortality rate from oral cancer for the past four decades has remained high at over 50% in spite of advances in treatment modalities. This contrasts with considerable decrease in mortality rates for cancers of the breast, colon, prostate, and melanoma during the same period. This book attempts to provide a reference-friendly update on the etiologic/risk factors, current clinical diagnostic tools, management philosophies, molecular biomarkers, and progression indicators of oral cancer.

new edition of the definitive Oral Cancer, provides a multidisciplinary approach to oral cancer prevention, diagnosis, treatment, and rehabilitation. The effective combination of both authoritative text and colored atlas has produced a thorough examination into this complex disease. Updates include (1) epidemiology, demographics and trends, (2) maxillofacial prosthetics, newer materials and advances in implants, and (3) managing complications in therapy. Expansions in this Fifth Edition comprise (1) new data on viral etiology, genetics and cell markers of oral cancer, and premalignant lesions, (2) diagnosis, staging, imaging, and nutrition, (3) genomics and molecular progression, (4) control of malignant lesions with newer data on agents, mechanisms, and the effectiveness of chemoprevention, and (5) additional illustrations in the MR imaging and PET scans section. New coverage incorporates (1) therapeutic advances in surgery, radiation, and chemotherapy, (2) newer agents, including combinations, radiation, survival morbidity, and quality of life, (3) newer and expanded tobacco data, along with smoking cessation, (4) sections on nutritional biochemistry and modern molecular analysis, and (5) new therapies for salivary gland malignancies.

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. Some of the discussed risk factors are well known, including smoking, alcohol, betel quid chewing, and oncoviruses such as high-risk human papillomaviruses and Epstein-Barr virus; however, careful attention is also paid to less widely recognized factors, such as Qat chewing and yerba Mate consumption. The book concludes by describing and evaluating the most important strategies currently available for the prevention of oral carcinogenesis in humans. In presenting the most up-todate research and knowledge on these topics, this book will serve as a valuable source of up-to-date information for oncologists, cancer scientists, and medical students.