Manual For The Microscopical Diagnosis Of Malaria In Man

Excerpt from Manual for the Microscopical Diagnosis of Malaria in Man This work is of especial use at this time when the expansion of the area of activity of our Army and Navy has brought many persons into malarious regions. I regard this publication as a clear, thorough, and timely treatment of an important subject. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

The first version of the WHO Malaria microscopy quality assurance manual (2009) was based on recommendations made at a series of informal consultations organized by WHO particularly a bi-regional meeting of the WHO regional offices for South-East Asia and the Western Pacific in April 2005 in Kuala Lumpur Malaysia followed by informal consultations held in March 2006 and February 2008 in Geneva Switzerland. Subsequently extensive consultations among international malaria experts led to consensus and preparation of the manual. This second version of the Manual is based on the recommendations of experts made at a WHO technical consultation in March 2014 in Geneva Switzerland. The aim of the meeting was to review the experiences of national malaria control programmes (NMCPs) national reference laboratories (NRLs) and technical agencies in using the Manual and country experience in order to improve systems for managing the quality of malaria microscopy. This second version takes into account the many years of experience of several agencies in the various aspects of quality assurance (QA) described in the Manual. In particular the sections on assessment of competence in malaria microscopy are based on use of this method by the WHO regional offices for South-East Asia and the Western Pacific in collaboration with the WHO Coordinating Centre for Malaria in Australia and by the WHO Regional Office for Africa in collaboration with Amref Health Africa. The section on setting up and managing an international reference malaria slide bank is based on the work of the WHO Regional Office for the Western Pacific in collaboration with the WHO Coordinating Centre for Malaria Diagnosis in the Philippines. The section on proficiency testing for malaria microscopy is based on work in the WHO Regional Office for Africa in collaboration with the National Institute for Communicable Diseases in South Africa and experience in regional initiatives by Amref Health Africa. The section on slide validation is based on work by Médecins sans Frontières and the section on outreach training and supportive supervision (OTSS) is based on work by the President's Malaria Initiative Malaria Care Project Medical Care Development International and Amref Health Africa. The Manual is designed primarily to assist managers of NMCPs and general laboratory services responsible for malaria control. The information is also applicable to nongovernmental organizations (NGOs) and funding agencies involved in improving quality management systems for malaria microscopy. The Manual is not designed for QA of microscopy in research situations such as in clinical trials of new drugs and vaccines or for monitoring parasite drug resistance. It forms part of a series of WHO documents designed to assist countries in improving the quality of malaria diagnosis in clinical settings including the revised training manuals on Basic malaria microscopy (2010) and the Bench aids for malaria microscopy (2010).

Early diagnosis and prompt, effective treatment is the basis for the management of malaria and key to reducing malaria mortality and morbidity. An acceptable microscopy service is one that is cost-effective, provides results that are consistently accurate and timely enough to have a direct impact on treatment. This requires a comprehensive and active quality assurance (QA) program. This manual outlines a hierarchical structure based on retraining, validation and the development of competency standards designed to ensure the quality of diagnosis necessary for a successful malaria program, while remaining within the financial and personnel resources likely to be available. The mode of implementation of the QA system outlined in this manual will vary according to the organization of the national laboratory services dealing with malaria, which may fall under the national malaria control program, or under a separate laboratory structure working closely with the malaria program.