Medical Image Synthesis

Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties. The benefits of medical image synthesis have sparked growing interest in a number of advanced clinical applications, such as magnetic resonance imaging (MRI)-only radiation therapy treatment planning and positron emission tomography (PET)/MRI scanning. This book will be a comprehensive and exciting resource for undergraduates, graduates, researchers, and practitioners.

Biomedical Image Synthesis and Simulation: Methods and Applications presents the basic concepts and applications in image-based simulation and synthesis used in medical and biomedical imaging. The first part of the book introduces and describes the simulation and synthesis methods that were developed and successfully used within the last twenty years, from parametric to deep generative models. The second part gives examples of successful applications of these methods. Both parts together form a book that gives the reader insight into the technical background of image synthesis and how it is used, in the particular disciplines of medical and biomedical imaging. The book ends with several perspectives on the best practices to adopt when validating image synthesis approaches, the crucial role that uncertainty quantification plays in medical image synthesis, and research directions that should be worth exploring in the future. Gives state-of-the-art methods in (bio)medical image synthesis Explains the principles (background) of image synthesis methods Presents the main applications of biomedical image synthesis methods

This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.

The three-volume set LNCS 10433, 10434, and 10435 constitutes the refereed proceedings of the 20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017, held inQuebec City, Canada, in September 2017. The 255 revised full papers presented were carefully reviewed and selected from 800 submissions in a two-phase review process. The papers have been organized in the following topical sections: Part I: atlas and surface-based techniques; shape and patch-based techniques; registration techniques, functional imaging, connectivity, and brain parcellation; diffusion magnetic resonance imaging (dMRI) and tensor/fiber processing; and image segmentation and modelling. Part II: optical imaging; airway and vessel analysis; motion and cardiac analysis; tumor processing; planning and simulation for medical interventions; interventional imaging and navigation; and medical image computing. Part III: feature extraction and classification techniques; and machine learning in medical image computing.

The six-volume set LNCS 11764, 11765, 11766, 11767, 11768, and 11769 constitutes the refereed proceedings of the 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2019, held in Shenzhen, China, in October 2019. The 539 revised full papers presented were carefully reviewed and selected from 1730 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: optical imaging; endoscopy; microscopy. Part II: image segmentation; image registration; cardiovascular imaging; growth, development, atrophy and progression. Part III: neuroimage reconstruction and synthesis; neuroimage segmentation; diffusion weighted magnetic resonance imaging; functional neuroimaging (fMRI); miscellaneous neuroimaging. Part IV: shape; prediction; detection and localization; machine learning; computer-aided diagnosis; image reconstruction and synthesis. Part V: computer assisted interventions; MIC meets CAI. Part VI: computed tomography; X-ray imaging.

This book constitutes the refereed proceedings of the Third International Workshop on Simulation and Synthesis in Medical Imaging, SASHIMI 2018, held in conjunction with MICCAI 2018, in Granada, Spain, in September 2018. The 14 full papers presented were carefully reviewed and selected from numerous submissions. This workshop continues to provide a state-of-the-art and integrative perspective on simulation and synthesis in medical imaging for the purpose of invigorating research and stimulating new ideas on how to build theoretical links, practical synergies, and best practices between these two research directions.

This book constitutes the refereed proceedings of the First International Workshop on Simulation and Synthesis in Medical Imaging, held in conjunction with MICCAI 2016, in Athens, Greece, in October 2016. The 17 revised full papers presented together in this book were carefully reviewed and selected from 21 submissions. The contributions span the following broad categories: fundamental methods for image-based biophysical modeling and image synthesis; biophysical and data-driven models of disease progression or organ development; biophysical and data-driven models of organ motion and deformation; biophysical and data-driven models of image formation and acquisition; segmentation/registration across or within modalities to aid the learning of model parameters; cross modality (PET/MR, PET/CT, CT/MR, etc.) image synthesis; simulation and synthesis from large-scale image databases; automated techniques for quality assessment of simulations and synthetic images; as well as several applications of image synthesis and simulation in medical imaging such as image registration and segmentation; image denoising and information fusion; image reconstruction from sparse data or sparse views; and real-time simulation of biophysical properties. The papers were divided into two general topics named “simulation based approaches for medical imaging” and “synthesis and its applications in computational medical imaging”.

This book constitutes the refereed proceedings of the Third International Workshop on Simulation and Synthesis in Medical Imaging, SASHIMI 2018, held in conjunction with MICCAI 2018, in Granada, Spain, in September 2018. The 14 full papers presented were carefully reviewed and selected from numerous submissions. This workshop continues to provide a state-of-the-art and integrative perspective on simulation and synthesis in medical imaging for the purpose of invigorating research and stimulating new ideas on how to build theoretical links, practical synergies, and best practices between these two research directions.