Medicinal Chemistry Of Drugs Affecting The Nervous System
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Medicinal Chemistry of Drugs Affecting the Nervous System
Author | : M. O. Faruk Khan ,Ashok E. Philip |
Publsiher | : Bentham Science Publishers |
Total Pages | : 406 |
Release | : 2020-09-24 |
Genre | : Medical |
ISBN | : 9789811454059 |
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The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of the chemical basis of drug action. Medicinal Chemistry of Drugs Affecting the Nervous System is the second volume of the series and it presents 8 chapters focusing on a comprehensive account of drugs affecting the nervous system. The volume informs readers about the medicinal chemistry of relevant drugs, which includes the mechanism of drug action, detail structure activity relationships and metabolism as well as clinical significance of drugs affecting autonomic and central nervous system. Chapters in this volume cover cholinergic drugs, adrenergic drugs, antipsychotics, antidepressants, sedatives, hypnotics, anxiolytics, antiepileptic drugs, anesthetics and antiparkinsonian drugs, respectively. Students and teachers will be able to integrate the knowledge presented in the book and apply medicinal chemistry concepts to understand the pharmacodynamics and pharmacokinetics of therapeutic agents in the body. The information offered by the book chapters will give readers a strong neuropharmacology knowledge base required for a practicing pharmacist.
Blood Brain Barrier in Drug Discovery
Author | : Li Di,Edward H. Kerns |
Publsiher | : John Wiley & Sons |
Total Pages | : 604 |
Release | : 2015-02-02 |
Genre | : Medical |
ISBN | : 9781118788356 |
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Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes • Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) • Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market
Drugs Affecting the Central Nervous System
![Drugs Affecting the Central Nervous System](https://youbookinc.com/wp-content/uploads/2024/06/cover.jpg)
Author | : A. Burger |
Publsiher | : Unknown |
Total Pages | : 437 |
Release | : 1968-01-01 |
Genre | : Electronic Book |
ISBN | : 0824710568 |
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Mechanisms of Drug Action on the Nervous System
Author | : R. W. Ryall |
Publsiher | : Cambridge University Press |
Total Pages | : 256 |
Release | : 1989-05-25 |
Genre | : Medical |
ISBN | : 0521254248 |
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Drugs affecting the nerves and the brain are among the most commonly used in contemporary medicine. This study examines the mechanisms by which such substances cause their therapeutic or undesirable side-effects in relation to underlying processes and pathological phenomena. The book fills the information gap between large textbooks and highly specialized reviews and monographs. Mechanisms of drug actions are examined mainly at the cellular and subcellular levels. Molecular, neurochemical and electrophysiological approaches are used in an attempt to provide a rational study of drugs acting on the nervous system.
Introduction to Neuropsychopharmacology
Author | : Leslie Iversen,Susan Iversen,Floyd E. Bloom,Robert H. Roth |
Publsiher | : Oxford University Press |
Total Pages | : 568 |
Release | : 2009 |
Genre | : Medical |
ISBN | : 9780195380538 |
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The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
Comprehensive Medicinal Chemistry II Volume 6
Author | : John Bodenhan Taylor,D. J. Triggle |
Publsiher | : Unknown |
Total Pages | : 872 |
Release | : 2007 |
Genre | : Business & Economics |
ISBN | : STANFORD:36105122424471 |
Download Comprehensive Medicinal Chemistry II Volume 6 Book in PDF, Epub and Kindle
This e-book comprises 8 volumes, with all chapter sections available as PDF or HTML, and includes bibliographical references and index.
Drugs Affecting the Peripheral Nervous System
Author | : Alfred Burger |
Publsiher | : Unknown |
Total Pages | : 558 |
Release | : 1968 |
Genre | : Medical |
ISBN | : UOM:39015003208116 |
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The Nervous System
Author | : Walter S. Root,Frederick G. Hofmann |
Publsiher | : Elsevier |
Total Pages | : 534 |
Release | : 2013-10-22 |
Genre | : Medical |
ISBN | : 9781483272948 |
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Physiological Pharmacology: A Comprehensive Treatise, Volume III: The Nervous System — Part C: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including cardiovascular effects and metabolism. The selection first offers information on the cardiovascular effects of choline esters and the effects of choline esters on smooth muscles and secretions. Topics include actions of acetylcholine, physiological role of choline esters, and actions of cholinergic drugs on smooth muscles and secretions. The book also takes a look at the pharmacologic, toxicologic, and therapeutic properties of anticholinesterase agents, including the chemistry and metabolism of anticholinesterase substances and mechanisms of action of anticholinesterase agents and role of cholinesterases. The publication examines muscarinic blocking drugs and ganglion-blocking drugs. Discussions focus on actions on the secretory glands and cardiovascular system; distribution, metabolism, and excretion of atropine; substances that block ganglionic transmission; and cardiovascular effects. The text also elaborates on neuromuscular blocking drugs. The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.