Metal Nanoparticles For Drug Delivery And Diagnostic Applications

Metal Nanoparticles for Drug Delivery and Diagnostic Applications addresses the lifecycle of metal nanoparticles, from synthesis and characterization, to applications in drug delivery and targeting. It is an important resource for those in biomaterials, nanomedicine and pharmaceutical sciences, exploring gold, silver and iron-based drug delivery systems for controlled and targeted delivery of potential drugs and genes for enhanced clinical efficacy. Nanotechnology is widely used in drug delivery due to its ability to reduce plasma fluctuation of drugs, high solubility, and efficiency, the relatively low cost of nanoscale products, and enhancement of patient comfort, hence this resource is a welcome edition to the science. Illustrates the progression of nanoparticle therapeutics from basic research to applications Explores new opportunities and ideas for developing and improving technologies in nanomedicine and nanobiology Discusses the toxicity of different types of metal nanoparticles and how to ensure their safe use

A much-needed summary of the importance, synthesis and applications of metal nanoparticles in pharmaceutical sciences, with a focus on gold, silver, copper and platinum nanoparticles. After a brief introduction to the history of metal complexes in medicine and fundamentals of nanotechnology, the chapters continue to describe different methods for preparation of metal nanoparticles. This section is followed by representative presentations of current biomedical applications, such as drug delivery, chemotherapy, and diagnostic imaging. Aimed at stimulating further research in this field, the book serves as an reference guide for academics and professionals working in the field of chemistry and nanotechnology.

The book covers the use of nanoparticles in therapeutics, diagnostics, and drug delivery. Topics covered include nanomaterial fabrication, surface modification and applications; toxicity of plant-based nanomaterials; the use of herbal extracts; bioimaging; metal doped nanoparticles for drug delivery; nanoparticles designed for specific neurodegenerative conditions; theranostic nanoparticles in treating lung diseases; and glioma nanotherapy. Keywords: Nanoparticles, Toxicity, Plant-based Nanomaterials, Bioimaging, Diagnostic Nanotechnologies, Metal Doped Nanoparticles, Wound Healing, Neurodegenerative Diseases, Theranostic Nanoparticles, Lung Diseases, Glioma Therapy, Drug Delivery Systems.

The book covers the use of nanoparticles in therapeutics, diagnostics, and drug delivery. Topics covered include nanomaterial fabrication, surface modification and applications; toxicity of plant-based nanomaterials; the use of herbal extracts; bioimaging; metal doped nanoparticles for drug delivery; nanoparticles designed for specific neurodegenerative conditions; theranostic nanoparticles in treating lung diseases; and glioma nanotherapy. Keywords: Nanoparticles, Toxicity, Plant-based Nanomaterials, Bioimaging, Diagnostic Nanotechnologies, Metal Doped Nanoparticles, Wound Healing, Neurodegenerative Diseases, Theranostic Nanoparticles, Lung Diseases, Glioma Therapy, Drug Delivery Systems.

Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

This handbook explains the application of nanoparticles in medical diagnosis and treatment. It is a ready reference on the subject, starting with the introduction to nanoparticles and progressing to synthetic procedures for nanotherapeutics, human disease diagnosis and nanocarrier-based drug delivery. The book also covers information about specific nanoparticle conjugates, in which nanoparticles are combined with drugs or nucleic acid strands (DNA, siRNAs, shRNAs, miRNAs) as well as topics of relevant to this field such as immunotherapy and vaccination development strategies. Each chapter also provides references for further reading. A Comprehensive Guide to Nanoparticles in Medicine is an ideal resource for scholars in medicine, pharmacology and technology who require an understanding to some basic facets of nanoparticles.

Nanomedicine is a developing field that includes different disciplines such as material science, chemistry, and engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification has allowed their use in drug-delivery systems, gene-therapy delivery and various types of theranostic approaches. Colloidal noble metal nanoparticles and other nanostructures have many therapeutic and diagnostic applications. The concept of drug targeting as a magic bullet has led to much research in chemical modification to design and optimize the binding to targeted receptors. It is important to understand the precise relationship between the drug and the carrier, and its ability to target specific tissues, and pathogens to make an efficient drug-delivery system. This book covers advances based on different drug-delivery systems: polymeric and hyper-branched nanomaterials, carbon-based nanomaterials, nature-inspired nanomaterials and pathogen-based carriers

This book highlights application of nanomaterials for drug delivery, therapy, and engineering. It covers stimuli-sensitive drug delivery systems including an overview of the physical, chemical, biological, and multi-stimuli-responsive nanosystems. It also presents analysis of clinical status for different types of nanoplatforms and assesses novel applications of nanomaterials in the areas of smart delivery and drug targeting. It further discusses the advantages and disadvantages of each application of pertinent nanomaterials. Features: Provides academic introduction to the uses of nanotechnology in drug delivery. Discusses use of nanomaterials in targeting a drug to specific tissues and cells. Presents an analysis of clinical status for different types of nanoplatforms. Covers applications in drug delivery, therapy, and engineering. Focuses on how novel nanotechnology-orientated methods can help improve treatment. This book is aimed at researchers and graduate students in biomedical and biochemical engineering, pharmaceutical, chemical and bioprocess engineering, materials science, and drug delivery mechanisms.