Microcirculation Revisited

The book provides a comprehensive overview of selected topics in microcirculation, from physiology to pathophysiology including molecular mechanisms and clinical aspects. It contains 10 chapters written by reputed authors, which comprehensively sum up the current knowledge and some interesting new insights in the field of microcirculation. It will be useful to a broad range of audience, from students to highly profiled experts, helping them to expand their knowledge on microcirculation and opening up additional questions for further investigation.

This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume

Microcirculation: Current Physiologic, Medical, and Surgical Concepts is based primarily on a course and a series of lectures presented at a congress on microcirculation held at the University of California in August 1979. The book gives an overview of the concepts regarding the structure and properties of small vessels, a topic mostly read only in specialized journals. The primary focus of the text is on the function and dysfunction of small blood vessels. Three major parts comprise the text. Part I discusses the morphology, physiology, and pharmacology of circulation, and Part II presents the dynamics or role of the microcirculation in the study of diabetes. Finally, Part III discusses also the role of microcirculation in disease states, particularly hemoconcentration. The book will provide much information to researchers and students in the fields of biology, medicine, physiology, and pharmacology.

First published in 1995: Clinically Applied Microcirculation Research combines state-of-the-art microcirculation technology with present and potential applications in clinical medicine. This comprehensive guide unites the expertise of clinicians and basic researchers from around the world. Many of the chapters are authored by scientist/physician teams. The book provides a broad overview of how microcirculation is involved in clinical research. This is also a valuable reference source for both the history of and latest developments in microcirculation research.

Microcirculation is key to providing enough nutrition and oxygen from head to toe. This is possible only through an extensive network of blood vessels spread around the body. Effect of microcirculation abnormalities stretch beyond one’s comprehension. The effects could be felt at any age, from the foetal life to the adulthood. The chapters present in this book describe how these abnormalities could lead to diseases such as atherosclerosis, thrombosis, diabetes, hypertension. Disorders of microcirculation could be related to the structural and/or functional damage to the inner lining of the blood vessels. Early identification of these disorders could benefit many ailments including cardiovascular and cerebrovascular diseases such as heart attack and stroke.

An Introduction to Microcirculation is written in response to the need for a book containing the most basic information about microcirculation. The book aims to consolidate information gained from the numerous vascular beds that have been used for in vivo microscopic observations, to note the similarities and differences in architecture and function, to reveal the origin of certain terms and concepts, and to discuss hemodynamics of the micro vessels. The book is divided into three parts. Part 1 covers a historical introduction to the study; general anatomical comparisons; the microvasculature of specific organs and tissues; and methods of preparation of tissues for microscopic observation. Part 2 discusses factors that are involved in this process and the exchange in the microcirculation. Part 3 explores the hemodynamics in the microcirculation and quantitative techniques for measurement of velocity and blood pressure. The text is for medical students, graduate students, clinicians, and young investigators who wish to have a greater knowledge on microcirculation and the concepts behind it.