Mitochondrial Dynamics And Neurodegeneration
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Mitochondrial Dynamics and Neurodegeneration
Author | : Bingwei Lu |
Publsiher | : Springer Science & Business Media |
Total Pages | : 260 |
Release | : 2011-05-16 |
Genre | : Medical |
ISBN | : 9789400712911 |
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Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.
Mitochondrial Dynamics and Neurodegeneration
Author | : Bingwei Lu |
Publsiher | : Springer |
Total Pages | : 260 |
Release | : 2013-01-02 |
Genre | : Medical |
ISBN | : 9400712928 |
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Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.
Molecular Links Between Mitochondrial Damage and Parkinson s Disease and Related Disorders
Author | : Yuzuru Imai,Kiyoung Kim,Zhihao Wu,Shigeto Sato |
Publsiher | : Frontiers Media SA |
Total Pages | : 165 |
Release | : 2021-09-28 |
Genre | : Science |
ISBN | : 9782889713912 |
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Mitochondrial Dysfunction in Neurodegenerative Disorders
Author | : Amy K. Reeve,Eve M. Simcox,Michael R. Duchen,Doug M. Turnbull |
Publsiher | : Springer |
Total Pages | : 380 |
Release | : 2016-06-08 |
Genre | : Medical |
ISBN | : 9783319286372 |
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This second edition brings together up-to-date contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. The reader is guided through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, and on to the consequences of this dysfunction for neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets. Additional chapters have been added to the book to reflect advances in the field and there are many new contributors and topics, including how mitochondria are degraded and the interaction of the mitochondria with pathologically relevant proteins. Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.
Mitochondrial Dysfunction and Neurodegeneration
Author | : Victor Tapias,Pier Giorgio Mastroberardino,Roberto Di Maio |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 2020 |
Genre | : Electronic Book |
ISBN | : OCLC:1368421940 |
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Mitochondrial Dysfunction in Neurodegenerative Disorders
Author | : Amy Katherine Reeve,Kim Jennifer Krishnan,Michael R. Duchen,Doug M. Turnbull |
Publsiher | : Springer |
Total Pages | : 242 |
Release | : 2011-12-09 |
Genre | : Medical |
ISBN | : 0857297007 |
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As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of these diseases, guiding the reader through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, to the consequences of this dysfunction on neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets. Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.
Mitochondrial Dysfunction and Neurodegeneration
Author | : Victor Tapias,Pier Giorgio Mastroberardino,Roberto Di Maio |
Publsiher | : Frontiers Media SA |
Total Pages | : 209 |
Release | : 2020-01-30 |
Genre | : Electronic Book |
ISBN | : 9782889634507 |
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Mitochondrial Neuropathies
Author | : Anonim |
Publsiher | : Academic Press |
Total Pages | : 252 |
Release | : 2019-06-15 |
Genre | : Medical |
ISBN | : 9780128172254 |
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Mitochondrial Neuropathies, Volume 146, brings together experts in a range of diseases that damage the nervous system to present the role of mitochondrial dysfunction in their particular field, with this new release focusing on Mitochondrial dysfunction in Alzheimer's Disease, HIV and the mitochondrial: immune interface in the CNS, The Impact of mitochondrial damage in HIV-induced peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of chemotherapy-induced peripheral neuropathy, Disorders of mitochondrial biogenesis in peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of diabetic neuropathy, Manipulating mitochondria to treat peripheral neuropathy, and DCA therapy - the yin and yang of mitochondrial activation. Contains contributions from a diverse group of experts Presents a timely resource that brings together different fields to highlight a common pathogenic mechanism Focuses on the role of mitochondria in diverse neuropathies