Molecular Basis Of Drug Design And Resistance
Download Molecular Basis Of Drug Design And Resistance full books in PDF, epub, and Kindle. Read online free Molecular Basis Of Drug Design And Resistance ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Molecular Basis of Drug Design and Resistance
Author | : G. H. Coombs,Leslie H. Chappell,S. L. Croft |
Publsiher | : Cambridge University Press |
Total Pages | : 172 |
Release | : 1997 |
Genre | : Medical |
ISBN | : 0521626692 |
Download Molecular Basis of Drug Design and Resistance Book in PDF, Epub and Kindle
This volume is the specially commissioned supplement to the journal Parasitology, volume 114.
The Organic Chemistry of Drug Design and Drug Action
Author | : Richard B. Silverman |
Publsiher | : Elsevier |
Total Pages | : 650 |
Release | : 2012-12-02 |
Genre | : Science |
ISBN | : 9780080513379 |
Download The Organic Chemistry of Drug Design and Drug Action Book in PDF, Epub and Kindle
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization
Molecular Docking for Computer Aided Drug Design
Author | : Mohane S. Coumar |
Publsiher | : Academic Press |
Total Pages | : 520 |
Release | : 2021-03-04 |
Genre | : Medical |
ISBN | : 9780128223123 |
Download Molecular Docking for Computer Aided Drug Design Book in PDF, Epub and Kindle
Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery. Covers the latest information and state-of-the-art trends in structure-based drug design methodologies Includes case studies that complement learning Consolidates fundamental concepts and current practice of molecular docking into one convenient resource
Structural Biology in Drug Discovery
Author | : Jean-Paul Renaud |
Publsiher | : John Wiley & Sons |
Total Pages | : 1367 |
Release | : 2020-01-09 |
Genre | : Medical |
ISBN | : 9781118900505 |
Download Structural Biology in Drug Discovery Book in PDF, Epub and Kindle
With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
Drug Design
Author | : Kenneth M. Merz,Dagmar Ringe,Charles H. Reynolds |
Publsiher | : Cambridge University Press |
Total Pages | : 289 |
Release | : 2010-05-31 |
Genre | : Medical |
ISBN | : 9780521887236 |
Download Drug Design Book in PDF, Epub and Kindle
This book provides a complete snapshot of various experimental approaches to structure-based and ligand-based drug design and is illustrated with more than 200 images.
Biochemical Protozoology As A Basis For Drug Design
Author | : Graham H. Coombs |
Publsiher | : CRC Press |
Total Pages | : 656 |
Release | : 1991-10-07 |
Genre | : Medical |
ISBN | : 9780748400010 |
Download Biochemical Protozoology As A Basis For Drug Design Book in PDF, Epub and Kindle
A compilation of articles on protozoological biochemistry which reviews the subject area and offers information on current research. Included in the Topics Covered Are Energy Metabolism Of Anaerobic Parasitic Protists, proteinases of African
Improving and Accelerating Therapeutic Development for Nervous System Disorders
Author | : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders |
Publsiher | : National Academies Press |
Total Pages | : 107 |
Release | : 2014-02-06 |
Genre | : Medical |
ISBN | : 9780309292498 |
Download Improving and Accelerating Therapeutic Development for Nervous System Disorders Book in PDF, Epub and Kindle
Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Drug Repurposing
Author | : Farid A. Badria |
Publsiher | : BoD – Books on Demand |
Total Pages | : 236 |
Release | : 2020-12-02 |
Genre | : Medical |
ISBN | : 9781839685200 |
Download Drug Repurposing Book in PDF, Epub and Kindle
Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.