Moyamoya Disease 2nd Edition

Moyamoya disease (MMD) is a chronic cerebrovascular disease characterized by progressive stenosis of the arteries of the circle of Willis, and formation of a collateral vascular network at the base of the brain. Moyamoya syndrome is caused by numerous conditions, which lead to arterial occlusion of the circle of Willis and resultant collaterals reminiscent of moyamoya disease. Due to the diverse angioarchitecture and unknown influence factors, the hemodynamic disturbances of MMD/Moyamoya syndrome are complicated, and result in multimodal clinical manifestations including headache, cognitive impairment, seizures, TIA, infarction, and hemorrhage. Surgical revascularization has been proven as effective in decreasing incidence of long-term risk of stroke. However, occurrence of perioperative stroke and complications such as seizures and cerebral hyperperfusion syndrome are still unpredictable. In addition, many patients with cognitive impairment cannot benefit from surgical revascularization and the mechanism remains unclear. Thus, a series of studies focusing on the objective evaluation of MMD/Moyamoya syndrome are needed to help understand this complicated cerebrovascular disease and improve our treatment strategy. The goal of this Research Topic is to better understand the pathophysiological nature of MMD/Moyamoya syndrome through objective neuroimaging. We also aim to generate a reasonable and objective evaluation system for MMD/ Moyamoya syndrome and would like to understand the link between cognitive impairment and brain damage of MMD/Moyamoya syndrome though neuroimaging. Through these findings we also aim to improve the treatment strategy by understanding the pathophysiological link with relevant complications. Finally, we also aim to improve our understanding of the significance of perioperative management for patients with severe complications from the perspective of objective evaluation.

This book brings together the latest knowledge on moyamoya disease, covering diagnostic criteria, status as a disease entity, genetic aspects, pathophysiology, novel neuroradiological findings, and surgical therapy. Information is also provided on recent basic and clinical research with the aim of identifying future perspectives on the disease. Since moyamoya disease was first reported in an English language article more than 50 years ago, our understanding of it has advanced considerably. Genetic and radiological analysis has delivered novel insights, and the latest multicenter studies are changing routine diagnosis and surgical therapy. The gene encoding the ring finger protein 213 (RNF213) has been identified as a susceptibility gene for moyamoya disease. Indications and procedures for surgical revascularization have been revised, with resultant improvements in outcomes, and studies performed over the past decade have provided new knowledge on the neuroradiological findings before and after surgery. In describing these advances, this book will be an invaluable asset for all general physicians, pediatricians, neurologists, radiologists, and neurosurgeons who care for patients with moyamoya disease across the world.

Toole's Cerebrovascular Disorders was the first modern book devoted to care of the stroke, originally published more than 40 years ago. This is a completely revised and updated sixth edition of the highly respected standard for stroke diagnosis and treatment. Dr James Toole has stayed on as a consultant for the text, and Drs E. Steve Roach, Kerstin Bettermann, and Jose Biller have reworked Dr Toole's book to include chapters on genetics, pregnancy-related stroke, and acute treatments. The practical focus of the book has not changed, retaining its emphasis on bedside diagnosis and treatment. Easily accessible both for stroke specialists and residents, the sixth edition has been modernized to keep pace with the rapid expansion of knowledge in stroke care and includes evidence-based recommendations, the latest technology and imaging, and risk factors. The text is supplemented with more than 200 images, many in color.

This volume provides an overview of new concepts in neurovascular interventions based on clinical and scientific knowledge of cerebrovascular disorders. It especially focuses on subarachnoid hemorrhage and cerebrovascular malformations, e.g. aneurysms, arterio-venous malformations, and cavernomas. A separate part addresses cerebral revascularization for both complex aneurysms and ischemia. All contributions were written by recognized experts and cover original papers presented at the 7th European Japanese Stroke Surgery Conference, held in Verona, Italy in June 2014. The authors present new trends and strategies for managing emerging problems, as well as in-depth discussions on controversial issues in the field.

This book will discuss and cover standard treatments and advances in some of the most controversial topics in cerebrovascular surgery traversing the whole arena, including open and interventional surgeries. They will be discussed with case scenarios, bail out strategies and complication handling, followed by advances in the subject. Some of the best academic cereberovascular physician will author these chapters with their vast experience. The book will be of particular benefit to neurosurgeons, neurologists, and radiologists. It will be particularly targeting residents, young and experienced faculty in the subject, and will provide first hand up to the mark information and experiences in cerebrovascular surgery.

"Why a second edition of the text book - Goodman's Neurosurgery Oral Board Review? The American Board of Neurological Surgery Oral Examination is the important final step in the certification process of a neurosurgeon. The examination has been in a constant state of evolution over the last 75 years. A major change in the examination process occurred in 2017, and the details of this transition are nicely outlined in Chapter 1. In keeping with this significant change in the Oral Board Examination format - I felt that the Goodman course needed to change to keep up with the Examination - see Chapter 3. The 2nd edition of the book now also reflects these updates with an emphasis on how to prepare for the current exam format. "--

This is an open access proceeding book of 9th European-Japanese Cerebrovascular Congress at Milan 2018. Since many experts from Europe and Japan had very important and fruitful discussion on the management of Cerebrovascular diseases, the proceeding book is very attractive for the physician and scientists of the area.

This book answers frequently asked questions about common pediatric neurosurgical conditions related to vascular malformations of the brain and spinal cord, in an attempt to fill in the gap and answer numerous questions that arises after a diagnosis is made. Pediatric patients with neurosurgical conditions are almost always referred from either primary care physicians, neurologists internists or a specialist in family medicine. Recently, neurosurgeons treating adult population also refer a pediatric patient to their colleague specialized in this field. There are over 1500 academic and private hospitals in the US who have dedicated tertiary Neurosurgery services and cater thousands of small children every year, in addition to numerous centers that have level 1 and 2 trauma care. However, there are few tertiary level Pediatric centers which can provide quality care for neurosurgical conditions. This book is specially written and illustrated for residents, fellows and consultants/attendings in all pediatric related specialties, including but not limited to Neurosurgery, Neurology, Pediatrics, Radiology, Anesthesia.