Nanobiomaterial Engineering

This book comprehensively documents the application of Nanobiomaterials in the field of bio-medicine and diagnostics technologies by involving classical concepts/examples. Nanobiotechnology is an emerging area which encompasses all the facets of research of nano and biomaterials with their interaction with biological systems. The book briefly summarizes the various types of Nanomaterial’s, and highlights the recent developments in the synthesis of the nanomaterials for the diagnostic and therapeutic biomedical applications. It skilfully reviews the utilization of the nanomaterials alone or in combination with other bio-molecules as a contrast enhancer in in-vivo imaging, Nano-Theranostics, drug delivery, and sensing transducer matrix. It also discusses the current research on designing of the new Nanobiomaterials and their implementation in numerous fields including bio-medicine and diagnostics. Finally, it summarizes the future prospects and the commercial viability of Nanobiomaterials in the human health care.​

There is a continuous exchange of ideas taking place at the border of the biological and physical sciences in many areas of nanoscience. Nanotechnology uses biomimetic or bio-inspired processes to produce nanosized materials for applications in biology and other fields. In return, the fruits of nanotechnology are applied to expanding areas of biomedical and therapeutic processes, such as new nanostructures and scaffolds for tissue engineering or targeted drug delivery. In this way, nanobiotechnology serves as a bridge between nano and bio, with nanoscale materials providing the building blocks for the construction of the "bridge." Nanobiomaterials: Development and Applications gives you a broad, interdisciplinary view of current developments as well as new findings and applications in bionanomaterials. The book brings together the work of international contributors who are actively engaged at the forefront of research in their respective disciplines. Organized into four parts, this book explores the preparation and characterization of nanomaterials, new preparation routes of soft nanomaterials using biomolecules, nano- and microscale hybridization of materials, and nanotoxicity. The contributors cover a diverse set of topics, including: Biomimetic synthesis Bioimaging and cancer diagnosis Photodynamic therapy Bioconjugated carbon nanotube DNA transfection and tumor targeting Magnetically induced hyperthermia Cytotoxity mechanisms and their potential use in therapy Virus-enabled manufacturing of functional nanomaterials Biocatalitic nanosystems and enzyme immobilization Tissue engineering The fabrication of hybrid microswimmers Bionanomaterial applications in environmental remediation Each chapter is richly illustrated and includes an extensive list of references to guide you toward further research. Combining bionanomaterial development and applications, the book clearly demonstrates the importance of these materials to biotechnology, biomedicine, and environmental remediation. It offers an accessible overview for students, industrial researchers, pharmaceutical innovators, medical and public health personnel, environmental scientists and engineers, and anyone interested in this interdisciplinary field.

Nanomaterial technologies can be used to fabricate high-performance biomaterials with tailored physical, chemical, and biological properties. They are therefore an area of interest for emerging biomedical technologies such as scaffolding, tissue regeneration, and controlled drug delivery. Nanomaterials in tissue engineering explores the fabrication of a variety of nanomaterials and the use of these materials across a range of tissue engineering applications. Part one focuses on the fabrication of nanomaterials for tissue engineering applications and includes chapters on engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials. Part two goes on to highlight the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering. Finally, the use of nanomaterials in hard tissue engineering applications, including bone, dental and craniofacial tissue engineering is discussed in part three. Nanomaterials in tissue engineering is a standard reference for researchers and tissue engineers with an interest in nanomaterials, laboratories investigating biomaterials, and academics interested in materials science, chemical engineering, biomedical engineering and biological sciences. Explores the fabrication of a variety of nanomaterials and their use across a range of tissue engineering applications Examines engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials Highlights the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering

Nanobiomaterials in Hard Tissue Engineering covers the latest developments in the field of hard tissue engineering at the nanoscale. Leading researchers from around the world discuss the latest research and offer new insights. This book presents data about the fabrication and characterization of nanobiomaterials involved in hard tissue reconstruction, describing recent progress and the advantages of both conventional and computer-aided methods. Recent applications of different classes of nanobiomaterials are discussed, with in vitro and in vivo applications also explained in detail. Special attention is paid to the applications of nanobiomaterials in bone regeneration and in the development of functional coatings for tailored implants to improve osseointegration. Finally, the book considers future challenges and perspectives. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. An up-to-date and highly structured guide for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A detailed and invaluable overview of hard tissue engineering, an increasingly important field Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Engineering of Nanobiomaterials: Applications of Nanobiomaterials brings the most recent evidence regarding the specific modifications of nanomaterials and their synthesis methods in order to obtain particular structures for different bio-medical purposes. The book presents the results of current research to reach those who wish to use this knowledge in an applied setting, providing readers with a collection of titles that brings together many of the novel applications these materials have in biology, also discussing the advantages and disadvantages of each application and the perspectives of the technologies based on these findings. At the moment there is no other comparable book series covering all the subjects approached in this set of titles. Presents an updated and highly structured reference material for students, researchers, and practitioners working in the bio- medical, biotechnological, and engineering fields Provides a valuable resource of recent scientific progress, along with most known applications of nanomaterials in the biomedical field Includes novel opportunities and ideas for developing or improving engineering technologies in nanomedicine/nanobiology

This book fills the gap between fundamental and applied research in the use of nanomaterials in biomedical applications, covering the most relevant areas, such as the fundamental concepts of the preparation of nanostructures and regulatory requirements for their safe use in biomedical devices. It also critically discusses what has been achieved in the field, and what needs to be urgently addressed and reviews the state-of-the-art medical uses of nanomaterials for treating damaged organs and tissues. Combining the expertise of clinical researchers working in the field of tissue engineering and novel materials, the book explores the main topics regarding the characterization of materials, specific organ-oriented biomaterials and their applications, as well as regulations and safety. Further, it also examines recent advances, difficulties, and clinical requirements in terms of human bone, cornea, heart, skin and the nervous system, allowing readers to gain a clear and comprehensive understanding of current nanomaterial use in biomedical applications and devices, together with the challenges and future trends. This book is a valuable tool for multidisciplinary scientists and experts interested in fundamental concepts and synthetic routes for preparing nanomaterials. It is also of interest to students and researchers involved in cross-disciplinary research in nanomaterials for clinical applications and offers practical insights for clinicians as well as engineers and materials scientists working in nanoengineering.

Nanotechnology in Medicine and Biology brings together a multidisciplinary team of experts from the fields of materials science, nanotechnology, medicine and biomedical engineering to introduce new nanoscale biomaterials and their applications, diagnosis and treatment of disorders of the human body. The book presents the fundamentals for understanding the design, properties and selection of nanobiomaterials as well as their real-world applications in medicine. Each chapter addresses current regulations, manufacturing processes, and translation issues of nanobiomaterials for key applications. A discussion of current protocols and their benefits and disadvantages is also included. This book provides comprehensive background and knowledge in the field of nanobiomaterials that is suitable for academics, scientists and clinicians. Provides fundamental understanding on the design, properties and selection of biomaterials for applications in medicine and biology Reviews current regulations, protocols, manufacturing processes and translation issues of nanobiomaterials for medical applications Discusses tissue repair, wound healing, regenerative medicine, drug delivery, imaging and medical device applications

Written by an international team of editors and contributors from renowned universities and institutes, this book addresses the latest research in the field of nanobiomaterials, covering nanotechnologies for their fabrication, developments in biomedical applications, and the challenges of biosafety in clinic uses. Clearly structured, the volume defines the scope and classification of the field, resulting in a broad overview from fundamental principles to current technological advances, and from materials synthesis to biomedical applications along with future trends.