Nanobiomedicine

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

This book provides that knowledge needed to introduce individuals to the most important research and content on nanotoxicology in nanobiomedicine. Nanotechnology is helping to considerably improve, even revolutionize many technology and industry sectors: information technology, homeland security, medicine, transportation, energy, food safety, and environmental science, among many others. There is an urgent need for a general reference textbook that presents the most recent information on the toxicity and its effects in all these sectors, biomedicine in particular. It includes historical information, nanotoxicology by subject area and or disease, sources of nanomaterials, drug delivery systems and more. Scientists, researchers, and students in all fields that use nanotechnology will find this book essential reading.

This book describes the latest advancements in molecular and cellular engineering approaches in addition to nanotechnology for cancer therapeutics and imaging. It also provides an excellent background and state-of-the-art developments in the fields of drug and gene delivery, engineering nanoparticles for therapy and diagnostics, and cancer imaging techniques. The contents of this book include chapters on cutting-edge science in molecular and cellular engineering and nanotechnology as applied to therapeutics and imaging in cancer diseases. The chapters also provide a comprehensive overview on gene therapy and delivery methods for cancer treatment, oral drug delivery and barriers, cancer imaging for diagnostics and therapy, and the latest developments in these fields. Contents: Optically Modulated Theranostic Nanoparticles (Niksa Valim & Amit Joshi)Gene Therapy Treatments for Cancer (Jacob Elmer)Nanocarrier based Pulmonary Gene Delivery for Lung Cancer: Therapeutic and Imaging Approaches (Nishant S Gandhi, Micah Glasgow & Mahavir B Chougule)Quantitative Contrast Enhanced Ultrasound Imaging in Cancer Therapy (Shashank R Sirsi & Mark A Borden)Multifunctional Dendritic Nanoparticles as a Nanomedicine Platform (Hao-jui Hsu, Ryan M Pearson & Seungpyo Hong)Oral Drug Delivery Systems for Gastrointestinal Cancer Therapy (Yue-Wern Huang & Sutapa Barua)Cancer Therapeutics with Light: Role of Nanoscale and Tissue Engineering in Photodynamic Therapy (Joyce Liu, Huang-Chiao Huang, Emma Briars, Girgis Obaid, Imran Rizvi & Tayyaba Hasan)Targeted Contrast Agents for 1H MRI of Tumor Microenvironment (Shubhangi Agarwal & Vikram D Kodibagkar)Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as Anti-Cancer Delivery Systems for Therapy and Diagnostics (Samuel V Mussi & Vladimir P Torchilin) Readership: Students and researchers in nanobiotechnology, nanomedicine, cancer research, bioengineering and medical imaging. Keywords: Nanobiotechnology;Nanomedicine;Nanoparticles;Cancer Research;Cancer Therapy;Gene Therapy;Bioengineering;Medical ImagingReview: Key Features: Novel aspects in cancer therapeutic delivery, comprehensive molecular and cellular aspects of cancer delivery and imaging, latest advanced in nanotechnology for cancer

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

This book consists of 4 volumes containing about 70 chapters covering all the major aspects of the growing area of nanomedicine. Leading scientists from 15 countries cover all major areas of nanobiomedical research materials for nanomedicine, application of nanomedicine in therapy of various diseases, use of nanomedicines for diagnostic purposes, technology of nanomedicines, and new trends in nanobiomedical research. This is the first detailed handbook specifically addressing various aspects of nanobiomedicine. Readers are treated to cutting-edge research and the newest data from leading researchers in this area.Contents: "Materials for Nanomedicine: "Liposomal Nanomedicines "(Amr S Abu Lila, Tatsuhiro Ishida and Theresa M Allen)"Solid Lipid Nanoparticles for Biomedical Applications "(Karsten Mader)"Micellar Nanopreparations for Medicine "(Rupa Sawant and Aditi Jhaveri)"Nanoemulsions in Medicine "(William B Tucker and Sandro Mecozzi)"Drug Nanocrystals and Nanosuspensions in Medicine "(Leena Peltonen, Jouni Hirvonen and Timo Laaksonen)"Polymeric Nanosystems for Integrated Image-Guided Cancer Therapy "(Amit Singh, Arun K Iyer and Mansoor M Amiji)"Polysaccharide-Based Nanocarriers for Drug Delivery "(Carmen Teijeiro, Adam McGlone, Noemi Csaba, Marcos Garcia-Fuentes and Maria J Alonso)"Dendrimers for Biomedical Applications "(Lisa M Kaminskas, Victoria M McLeod, Seth A Jones, Ben J Boyd and Christopher J H Porter)"Layer-by-Layer Nanopreparations for Medicine Smart Polyelectrolyte Multilayer Capsules and Coatings "(Rawil F Fakhrullin, Gleb B Sukhorukov and Yuri M Lvov)"Inorganic Nanopreparations for Nanomedicine "(James Ramos and Kaushal Rege)"Silica-Based Nanoparticles for Biomedical Imaging and Drug Delivery Applications "(Stephanie A Kramer and Wenbin Lin)"Carbon Nanotubes in Biomedical Applications "(Krunal K Mehta, Elena E Paskaleva, Jonathan S Dordick and Ravi S Kane)"Core-Shell Nanoparticles for Biomedical Applications "(Mahmoud Elsabahy and Karen L Wooley)"Structure Activity Relationships for Tumor-Targeting Gold Nanoparticles "(Erik C Dreaden, Ivan H El-Sayed and Mostafa A El-Sayed)"Silver Nanoparticles as Novel Antibacterial and Antiviral Agents "(Stefania Galdiero, Annarita Falanga, Marco Cantisani, Avinash Ingle, Massimiliano Galdiero and Mahendra Rai)"Magnetic Nanoparticles for Drug Delivery "(Rainer Tietze, Harald Unterweger and Christoph Alexiou)"Quantum Dots as a Platform Nanomaterial for Biomedical Applications "(Eleonora Petryayeva, Roza Bidshahri, Kate Liu, Charles A Haynes, Igor L Medintz, and W Russ Algar)""Applications in Therapy: "The Application of Nanomedicine to Cardiovascular Diseases "(Kevin M Bardon, Olivier Kister and Jason R McCarthy)"Nanomedicines for Restenosis Therapy "(J E Tengood, I Fishbein, R J Levy and M Chorny)"Nanopreparations for Cancer Treatment and Diagnostics "(Jayant Khandare, Shashwat Banerjee and Tamara Minko)"Nanoparticles in the Gastrointestinal Tract "(Abraham Rubinstein)"Nanopreparations for Oral Administration "(D Hubbard, D J Brayden and H Ghandehari)"Nanopreparations for Central Nervous System Diseases "(Leyuan Xu and Hu Yang)"Nanoparticles for Dermal and Transdermal Delivery: Permeation Pathways and Applications "(Marianna Foldvari, Marjan Gharagozloo and Christine Li)"Lysosomes and Nanotherapeutics: Diseases, Treatments, and Side Effects "(Rachel L Manthe and Silvia Muro)"Nanostructured Biomaterials for Inhibiting Cancer Cell Functions "(Lijuan Zhang and Thomas J Webster)"Nanomedicine in Otorhinolaryngology"

This book focuses on the materials, synthetic methods, tools and techniques being developed in the nanoregime towards the life sciences -- in particular biology, biotechnology and medicine. Readers from materials science, engineering, chemistry, biology and medical backgrounds will find detailed accounts of the design and synthesis of nanomaterials and the tools and techniques involved in their production for applications in biology, biotechnology and medicine.

Medical Nanotechnology and Nanomedicine introduces non-experts to the world of nanomedicine and its evolving organizational infrastructure. Considering the fluid nature of nano breakthroughs and the delicate balance between benefits and consequences as they apply to medicine, readers at all levels will gain a practical, understandable base of information on these developments so that they may take the greatest advantage of them. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects and provides an ideal foundation upon which to plan and make decisions.