Neuromuscular Case Studies

Ideal for neurologists and other health care professionals who treat patients with neuromuscular diseases, Neuromuscular Case Studies, 2nd Edition, presents more than 100 cases of both common and rare neuromuscular disorders. Dr. Tulio E. Bertorini provides the latest tools and strategies for diagnosis and management that minimize disability and maximize quality of life for your patients, including up-to-date coverage of numerous recent advances in the field. Using a multidisciplinary approach, this practical text contains two parts: the first includes basic aspects of anatomy, physiology, diagnostic tests, and therapeutic strategies; the second describes specific cases and their diagnosis and management. Presents a multidisciplinary approach to the management and therapeutic treatment of the full range of neuromuscular disorders and resulting complications. Covers the latest advances in the field, including genetic causes of hereditary diseases, new autoimmune diseases, and promising new therapies such as antisense oligonucleotides, gene therapies, and immunotherapy. Includes the wide range of disorders that fall under each disease classification (e.g., the Motor Neuron Diseases chapter includes all forms of spinal atrophy, ALS, neuropathies and myopathies, as well as disorders of neuromuscular transmission). In turn, each disease section includes diagnosis and evaluation, treatment, outcome, and suggested readings. Uses a reader-friendly format that takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy. Reviews the etiologies, pathogenesis, differential diagnosis, and management of each disorder, helping you not only recognize its presentation, but also determine the best treatment plan. Arranges case studies and indexes both by complaint and by diagnosis. Features full-color clinical images and diagrams — along with numerous diagnosis tools, tables and treatment algorithms throughout — that make complex concepts easier to understand and apply. Shares the knowledge and experience of an expert in clinical neuromuscular care. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

In this unique book, Dr. Bertorini guides you through more than 100 cases that demonstrate the diagnosis and management of a wide range of common and rare neuromuscular disorders. No other reference boasts such a large array of clinical studies devoted to all areas of this broad topic! Each case study reviews the etiologies, pathogenesis, differential diagnosis, and management of a particular disorder, helping you not only recognize its presentation, but also determine a diagnosis and the best treatment plans for your patients. You’ll also find expert guidance on the basic mechanisms of neuromuscular disorders, clinical examination, and diagnostic tests—including EMG, muscle biopsy, genetic testing, and more. More than 100 detailed case studies explore both common and rare neuromuscular disorders and the treatment protocols for each, equipping you with the knowledge you need to confidently manage any challenge. Each case includes a summary of important points or highlights of the study. Case studies are arranged either by complaint or by diagnosis so that you can successfully manage your patients with or without an initial diagnosis. Comprehensive coverage of EMGs and nerve conduction studies and other diagnostic tests, including muscle and nerve biopsies and genetic testing, helps you accurately diagnose nerve, muscle, and neuromuscular transmission disorders. Detailed discussions of treatment plans and commonly used drugs enhance your management of autoimmune disorders, painful neuropathy, dysautonomia, and other neuromuscular disorders. A reader-friendly format takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy. More than 350 high-quality illustrations, including full-color patient photographs, biopsies, and EMG tracings, make complex concepts easier to understand and apply.

This book provides an accessible guide to neuromuscular disorders using case scenarios from the world-renowned MRC Centre for Neuromuscular Diseases at the National Hospital, Queen Square, London, UK. Fifty genetic and acquired disorders are presented in a practical, easy-to-read format, including those that are common and also some which are rare. Each case covers the history, examination and investigations, including neurophysiology, neuroradiology and neuropathology if appropriate. Discussions of each case include the differential diagnosis, useful clinical pointers and a brief summary of the management of the condition. Neuromuscular Disease: Case Studies from Queen Square is aimed at neurology trainees and consultant general neurologists.

This issue of Neurologic Clinics, guest edited by Dr. Aziz Shaibani, is devoted to Case Studies in Neuromuscular Disorders. This issue is one of four selected each year by the series Consulting Editor, Dr. Randolph W. Evan. Articles in this issue include: Myotonia, Muscular Dystrophy, Spinal Muscular Atrophy, Advances in Clinical Genetics, FSHD New Diagnosis and Therapies, Congenital Myasthenic Syndrome, Diabetic Amyotrophy, ALS: Management Problems, Diagnostic and Therapeutic Challenges in Myasthenia Gravis, Scapular Winging, Small Fiber Neuropathy, Myopathies, Distal Myopathies, Inflammatory Myopathies, Muscle Cramps, Misdiagnosis of IBM, and Immune Mediated Neuropathies.

EMG Lesion Localization and Characterization: A Case Studies Approach takes a unique approach to electrodiagnostic (EDX) medicine, using case studies and exercises to teach clinical reasoning and build technical skills. The first section presents basic principles, reviewing pertinent nerve and muscle anatomy, physiology, and pathophysiology along with study techniques, measurements, and pitfalls. The second section emphasizes how to most effectively utilize the book’s featured case studies, followed by 60 cases covering the range of disorders encountered in the EMG lab and organized by regional and multiregional disorders of the upper and lower extremities, brachial plexopathies, generalized disorders, and challenging cases. Through the EDX case studies, lesion localization and characterization are demonstrated and discussed step-by-step using a floating text box that tracks the findings for each case. Cases begin with the clinical features, which dictate the initial EDX studies performed. The results of those studies drive the next round of testing, which continues until the abnormality has been localized and characterized and a diagnosis is made. In this manner, the dynamic nature of electrodiagnostic testing and process of sequential study analysis is reinforced, just as it would be in the EMG laboratory. Authored by two leading experts in neurology and electrodiagnostic medicine, all aspects of lesion localization and characterization are extensively covered, including calculations of lesion severity for demyelinating conduction block and axon loss lesions and calculations of various types of motor unit action potential recruitment frequencies. The book features a large number of anatomical drawings, charts, and EDX images in order to illustrate the skills of lesion localization and characterization comprehensively. By conveying the “cognitive approach” to EDX medicine, EMG Lesion Localization and Characterization merges clinical knowledge with real-life cases to better instruct residents, fellows, technicians, and neuromuscular providers in the field of electrodiagnostic medicine. Key Features: Includes 60 cases covering all major neuromuscular disorders Presents basic and advanced anatomic, physiologic, pathophysiologic, and temporal principles and concepts pertinent to EDX medicine EDX studies are evaluated as they are collected, providing insight into the principles underlying electrodiagnostic medicine Through sequential step-by-step analysis of findings, the decision-making process required in the EMG laboratory is simulated Purchase includes access to the ebook for use on most mobile devices or computers

Diagnose neuromuscular disorders more quickly and accurately with Electromyography and Neuromuscular Disorders: Clinical-Electrophysiologic Correlations, 3rd Edition! State-of-the-art guidance helps you correlate electromyographic and clinical findings and use the latest EMG techniques to their fullest potential. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Successfully correlate electrodiagnostic findings with key clinical findings for more confident diagnoses. Clearly see how to apply what you’ve learned with abundant case studies throughout the book. Obtain relevant clinical guidance quickly and easily with an accessible, easy-to-read writing style that’s both comprehensive and easy to understand. Ensure correct EMG needle placement and avoid neurovascular injuries by referring to more than 65 detailed, cross-sectional anatomy drawings. Diagnose many newly defined genetic neuromuscular conditions based on their electrodiagnostic presentation. Stay up to date with must-know information on iatrogenic complications of electrodiagnostic studies. Visualize key concepts more easily with a brand-new full-color design, new artwork, and new photographs. Access Electromyography and Neuromuscular Disorders online, fully searchable, at www.expertconsult.com, along with more than 70 videos that allow you to see and hear the EMG waveforms discussed in the text, as well as a convenient "test yourself" module.

This updated and expanded new edition of a successful book describes genetic diagnostic entities of neuromuscular disorders. Neuromuscular syndromes are presented clinically either as a case study or as an overview from the literature, accompanied by text presenting molecular defects, and differential diagnosis. This collection of neuromuscular disorders features the differential clinical phenotypes related to each genotype and are representative of the whole spectrum of a genetic muscle disorder, helping the clinician and neuromuscular physician to make a diagnosis. Key points for each genetic disease are identified to suggest treatment, when available, or the main clinical exams useful in follow-up of patients. Genetic Neuromuscular Disorders: A Case-Based Approach is aimed at neuromuscular physicians and neurology residents.

Comprehensive, thoroughly updated, and expanded, Neuromuscular Disorders in Clinical Practice, Second Edition encompasses all disorders of the peripheral nervous system, covering all aspects of neuromuscular diseases from diagnosis to treatment. Mirroring the first book, this two-volume edition is divided into two parts. Part one discusses the approach to neuromuscular disorders, covering principles and basics, neuromuscular investigations, and assessment and treatment of neurological disorders. Part two then addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies, and miscellaneous neuromuscular disorders and syndromes. Neuromuscular Disorders in Clinical Practice, Second Edition is intended to serve as a comprehensive text for both novice and experienced practitioners. General neurologists as well as specialists in neuromuscular medicine and trainees in neuromuscular medicine, clinical neurophysiology and electromyography should find this book inclusive, comprehensive, practical and highly clinically focused. Additionally, specialists in physical medicine and rehabilitation, rheumatology, neurosurgery, and orthopedics will find the book of great value in their practice.