Neuropathology

This updated second edition provides a practical and succinct overview of basic neuropathology. Key concepts and basic principles are covered and discussed with particular focus on recent advances, classification, and genetics. Practical points are included to detail how to best use the neuropathology service and interpret the results of pathological tests. Neuropathology Simplified aims to aid the development of multidisciplinary teams and help clinical trainees understand recent advances in neuropathological disorders. The book is also relevant to trainee and resident neurologists, pathologists, and neurosurgeons.

Save time diagnosing neuropathology specimens with Neuropathology, part of the growing High-Yield Pathology Series. Dr. Anthony Yachnis and Dr. Marie Rivera-Zengotita help you review the key features of neuropathology specimens, recognize the classic look of each disease, and quickly confirm your diagnosis. A logical format, excellent color photographs, concise bulleted text, and authoritative content will help you accurately identify hundreds of discrete disease entities. Find information quickly and easily with a templated, easy-to-reference format and concise, bulleted text. Confirm your diagnoses with superb color photographs that demonstrate the classic appearance of each disease. Depend on authoritative information from leading experts in the field. Access the full text online, perform quick searches, and download all the images at www.expertconsult.com.

I was gratified by the most favorable reception and wide usage received by the first edition of this book. A decade seems to be a short period for a book on pathology, and yet it witnessed many important changes of concepts, along with a formidable growth of knowledge. The second edition required extensive reorganization. There are new chapters on mitochondriopathies, on peroxisomal diseases and on spongy myelino pathies. Major revisions and new additions were necessary in many chapters, for instance those on the dysplasias of the cerebral and of the cerebellar hemispheres, which were largely reorganized. The chapters on perinatal pathology were reordered and reorganized to give a more logical sequence of prenatal, perinatal and postnatal lesions. The entire text was worked over for brevity. A wealth of new references was added with the. aim of staying abreast with the literature up to summer 1988. All refer ences were double checked for errors. My gratitude goes to Mrs. Gisela Ropte and Mrs. Cynthia Bunker for their untiring, diligent help. As a result, this second edition is an essentially rewritten text. Advance in the prevention of human suffering is based on a thorough understand ing of the nature of disease. I hope that this text will continue to be of service in this behalf. Perhaps it may also reflect and foster the intellectual curiosity which makes the "reading of brains" so interesting an occupation. Gottingen, 1989 Reinhard L.

Unparalleled access to the entire central nervous system with over four hundred gross neuropathology images from adult and paediatric post-mortem tissues.

Covering all aspects of neuropathology, this updated volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training—both as a quick reference and as an efficient review to improve knowledge and skills. The third edition is an easy-to-use, one-stop reference for the most recent clinical, pathological, histological, and molecular knowledge in the field. It offers complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions, enabling you to arrive at the correct diagnosis and prepare actionable, useful reports. Incorporates new WHO Classification of Tumors of the Central Nervous System, 5th Edition Offers information on neoplasms of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, and vascular lesions, aiding you in arriving at the correct diagnosis Emphasizes surgical pathology but also provides significant content on nonneoplastic diseases that present with focal lesions, especially those that are potentially misinterpreted as neoplasms Contains a detailed molecular diagnostics chapter with a section on methylation profiling, which has become indispensable as a method of tumor classification Features new and updated chapters detailing several types of tumors that have been reclassified due to recent molecular driver information, cIMPACT-NOW recommendations, and the WHO Classification, 5th Edition

Neuropathology, a title in the Foundations in Diagnostic Pathology series, provides all of the latest and most essential information on neoplastic and non-neoplastic conditions of the central and peripheral nervous systems in a high-yield, easy-to-use format. Renowned expert Richard A. Prayson, MD, along with a premier group of neuropathologists, provides unparalleled, expert guidance on the evaluation and diagnosis of a broad spectrum of neuropathic entities using morphologic, immunohistochemical, and molecular genetic techniques. The consistent, practical format with a wealth of illustrations, at-a-glance boxes, and tables make this title ideal for quick reference. Obtain expert, practical guidance on each pathologic entity, including clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnosis, and prognostic and therapeutic considerations. Reference key information quickly and easily with a consistent, user-friendly format and at-a-glance boxes and tables throughout the text. Recognize all the nuances of how pathological lesions present through over 800 full-color illustrations. Practice with confidence and overcome your toughest challenges with advice from the top minds in neuropathology. Make optimal use of the latest approaches for diagnosing fat and air emboli, vascular diseases, trauma, congenital malformations, perinatal diseases and phacomatoses, demyelinating and dysmyelinating disorders, neurodegenerative diseases, infections, metabolic and toxic disorders, glial and non-glial tumors, skeletal muscle and peripheral nerve disorders, and more. Prepare for the future of neuropathology with a new information dedicated to neurotransmitters as they relate to diseases such as Parkinson's and the development of new drugs for these disorders. Apply the latest molecular diagnostic techniques to recognize tumor entities added to the most recent WHO classification of tumors of the central nervous system. Access the fully searchable text online at www.expertconsult.com, along with a downloadable image bank, illustrations, boxes, tables, and more.

At last, a much-needed route map to pediatric neuropathology. Up to now a comprehensive volume covering of pediatric neuropathology simply did not exist. This atlas is thus a unique, all-encompassing reference providing material on the fundamentals of brain disorders of the nervous system that can affect fetuses, infants and young children, as well as the essentials of diagnosis in developmental brain pathology and neuroimaging. Emphasising the characteristic morphology and a concise summary of clinical features, pathogenesis, and genetics, the generously illustrated atlas presents more than 100 disorders. This compilation is a valuable resource for pathologists, pediatric neurologists and neurosurgeons, geneticists, neonatologists, radiologists, and pediatricians.

Forensic Neuropathology provides superior visual examples of the more commonly encountered conditions in forensic neuropathology and answers questions that arise regarding neuropathological findings. The work includes values for frequently-encountered clinical assessments, and contains a more comprehensive summary of aging/dating of various neuropathological processes than is available in any other single current source. General pathology residents, forensic pathology and neuropathology fellows, and general pathologists and clinicians involved in referred cases will find this book extremely useful, as will individuals in allied fields such as law enforcement officers and attorneys. Forensic Neuropathology aims to: (1) provide a concise summary of practical information frequently needed in forensic neuropathology cases; (2) include selected material previously known but perhaps not significantly emphasized in current literature; and (3) where possible, to suggest aging/dating parameters for certain neuropathological findings relevant to forensic neuropathology testimony. As a selective reference, the volume emphasizes practical issues and focuses on the most commonly encountered issues among neuropathology and medical examiner professionals. * Over 800 high-quality full-color photographs, gross and microscopic as well as illustrative line drawings * Use of actual cases, briefly summarized and illustrated to emphasize key principles * Focuses on the most-commonly encountered cases as relate to forensic incident and covers these aspects in depth and detail