Neuroscience For Clinicians

"The aim of this book is to provide the clinician with a comprehensive and clinical relevant survey of emerging concepts on the organization and function of the nervous system and neurologic disease mechanisms, at the molecular, cellular and system levels. The content of is based on the review of information obtained from recent advances in genetic, molecular and cell biology techniques, electrophysiological recordings, brain mapping, and mouse models, emphasizing the clinical and possible therapeutic implications. Many chapters of this book contain information that will be relevant not only clinical neurologists but also to psychiatrists and physical therapists. The scope includes the mechanisms and abnormalities of DNA/RNA metabolism, proteostasis, vesicular biogenesis, and axonal transport and mechanisms of neurodegeneration; the role of the mitochondria in cell function and death mechanisms; ion channels, neurotransmission and mechanisms of channelopathies and synaptopathies; the functions of astrocytes, oligodendrocytes and microglia and their involvement in disease; the local circuits and synaptic interactions at the level of the cerebral cortex, thalamus, basal ganglia, cerebellum, brainstem and spinal cord transmission regulating sensory processing, behavioral state and motor functions; the peripheral and central mechanisms of pain and homeostasis; and networks involved in emotion, memory, language, and executive function"--

This book fills the need for an introductory text that opens the field up to the beginner and takes them to higher-level thinking about neuroscience. Neuroscience has captured the interest of students, professionals, and the general public. In fact it is so new, that there are very few books that gather it together in one text. Neuroscience is an amalgamation of many fields: psychology, cognitive science, chemistry, biology, engineering, philosophy, mathematics, and statistics. People who are new to the discipline have to be able to find their way through all of these fields together. In addition, they need to understand the highly technical lexicon, modeling methods, and theoretical assumptions used to describe brain structure, function, and the interaction between them. This book helps readers navigate the conventions used to describe the brain that developed through the years. The authors crystallize the complex modeling methods and technologies so that readers understand what they are saying and how to use them. They address the important underlying principles and important issues of neuroscience, with the debates and discussions that are ongoing as the field evolves. They also include many salient fine-grained details so that the book is not just an overview, but also a useful guide for many levels of readers.

A brief guide to the most important neuroscience concepts for all mental health professionals. Louis Cozolino helps clinicians to broaden their thinking and deepen their clinical toolbox through an understanding of neuroscience, brain development, epigenetics, and the role of attachment in brain development and behavior. The effective therapist must have knowledge of evolution and neuroanatomy, as well as the systems of our brains and how they work together to give rise to who we are, how we thrive, and why we suffer. This book will give clinicians all they need to understand the social brain, the developing brain, the executive brain, consciousness, attachment, trauma, memory, and the latest information about clinical assessment. Key figures and terms of neuroscience, along with numerous case examples, bring the material to life. Cozolino is one of the most gifted clinical writers on neuroscience, and his long- awaited pocket guide is a must- buy for any clinician working on the cutting edge of treatment.

An examination of adults who have been manipulated by divorcing parents. Parental Alienation Syndrome (PAS) occurs when divorcing parents use children as pawns, trying to turn the child against the other parent. This book examines the impact of PAS on adults and offers strategies and hope for dealing with the long-term effects.

As scientific knowledge grows about the role of the brain in mental disorder, no clinician can afford to be uninformed about neurobiology. This accessible primer provides the basic grounding in neuroscience that all contemporary mental health professionals need. Readers are first guided through the fundamentals of neuroanatomy, neurochemistry, and psychiatric genetics. Chapters then illuminate the neurobiological underpinnings of a range of frequently encountered disorders--including ADHD, substance abuse, mood and anxiety disorders, schizophrenia, and learning and cognitive problems--giving particular attention to the impact of psychosocial risk factors on the brain. Also examined are ways that both pharmacological and psychological interventions have been shown to alter brain chemistry as they bring about a reduction in symptoms.

This book bridges the gap between data scientists and clinicians by introducing all relevant aspects of machine learning in an accessible way, and will certainly foster new and serendipitous applications of machine learning in the clinical neurosciences. Building from the ground up by communicating the foundational knowledge and intuitions first before progressing to more advanced and specific topics, the book is well-suited even for clinicians without prior machine learning experience. Authored by a wide array of experienced global machine learning groups, the book is aimed at clinicians who are interested in mastering the basics of machine learning and who wish to get started with their own machine learning research. The volume is structured in two major parts: The first uniquely introduces all major concepts in clinical machine learning from the ground up, and includes step-by-step instructions on how to correctly develop and validate clinical prediction models. It also includes methodological and conceptual foundations of other applications of machine learning in clinical neuroscience, such as applications of machine learning to neuroimaging, natural language processing, and time series analysis. The second part provides an overview of some state-of-the-art applications of these methodologies. The Machine Intelligence in Clinical Neuroscience (MICN) Laboratory at the Department of Neurosurgery of the University Hospital Zurich studies clinical applications of machine intelligence to improve patient care in clinical neuroscience. The group focuses on diagnostic, prognostic and predictive analytics that aid in decision-making by increasing objectivity and transparency to patients. Other major interests of our group members are in medical imaging, and intraoperative applications of machine vision.

The new edition of this respected work presents a comprehensive review of basic mechanisms of fetal and neonatal brain development.

Most psychological disorders involve distressful emotions, yet emotions are often regarded as secondary in the etiology and treatment of psychopathology. This book offers an alternative model of psychotherapy, using the patient’s emotions as the focal point of treatment. This unique text approaches emotions as the primary source of intervention, where emotions are appreciated, experienced, and learned from as opposed to being regulated solely. Based on the latest developments in affective neuroscience, Dr. Stevens applies science-based interventions with a sequential approach for helping patients with psychological disorders. Chapters focus on how to use emotional awareness, emotional validation, self-compassion, and affect reconsolidation in therapeutic practice. Interventions for specific emotions such as anger, abandonment, jealousy, and desire are also addressed. This book is essential reading for clinicians practicing psychotherapy, social workers and licensed mental health counselors, as well as anyoe interested in the emotional science behind the brain.