New Frontiers In Medicine

This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

Recent years have witnessed an increasing awareness of the importance and relevance of creativity in social and psychological life. This has led to an awakening of research into creativity. The book "New Frontiers in Creativity" deals with themes that have emerged due to the expanding boundaries of research in creativity. These concern primarily new perspectives in regard to creativity, discovering of creativity in new populations and nurturing of creativity in new domains and spheres of action. The book presents four new perspectives concerning creativity. The first is a comprehensive model of creativity (by Kreitler) that does justice to the complexity of creativity in terms of the constitutive components, ranging from cognition through motivation, emotions, personality, psychopathology, behavior and the environment, focusing on the rich variety of variables in each of the components and their interactions. Another perspective focuses on creativity in the study and research of creativity (by Runco) by adopting meta-cognitive powerful tactics in the study and nurturing of creativity. A third new perspective describes the innovative methods and findings in neurophysiology of creativity, particularly in brain studies (by Shemyakina and Nagornova). The set of new perspectives is complemented by a description of the social processes characterizing the spread and maintenance of innovative ideas (by Fokas). The innovation in terms of populations is presented in the discussion of creativity in individuals diagnosed with dyslexia (by Cancer and Antonietti), in the controversial sphere of psychopathology (by Thys) and in the elderly (by Cohen-Shalev). Notably, the creativity of all three populations has been increasingly recognized in recent years. The third part of the book is devoted to creativity in various domains, including painting (by Vardi), psychotherapy (by Buzdugan, Grigore and Dinca), engineering (by Engel), architecture (by Casakin), sports (by Santos, Sampaio and Memmert) and nature (by Edlinger). The book includes 13 chapters, written by internationally known experts from different countriesâAustria, Belgium, Hungary, Italy, Israel, Portugal, Romania, Russia, and USAâresponsible for discoveries in the specific aspect of creativity with which they deal. The different chapters of the book present innovative approaches, based on empirical evidence and innovative methodologies. Thereby they contribute to the setting of the scene for new developments and new applications of creativity in the rapidly changing world that is in increasing need for creativity.

This book updates the reader about the latest bio-mechanical concepts underlying keratoconus diagnosis and the various treatment alternatives: from conventional alternatives with a real cost/benefit description, to some innovative alternatives that have come to the fore in recent years. It discusses the latest software and technology utilized in keratoconus diagnosis as well as the more innovative surgical techniques used to treat keratoconus. New Frontiers for the Treatment of Keratoconus represents an essential book for ophthalmologists and specialists in cornea and refractive surgery who are looking to position themselves at the forefront of the diagnosis and treatment of keratoconus.

Recent advances in two-dimensional electrophoresis, protein microanalysis and bioinformatics have made the large-scale, systematic analysis of proteins and their post-translational modifications from any tissue or organism possible. This approach has acquired the name "Proteome Research", and can be considered as the core of functional genomics. The results of proteome analysis show which genes are expressed, how the protein products are modified, and how they interact, making proteome research of fundamental importance for the biologist, clinician, and pharmaceutical industry.

Rapid advances in stem cell biology have raised exciting possibilities of replacing damaged or lost tissues and cells by activation of in vitro-expanded stem cells or their progeny. This book examines many of the unresolved problems as well as future applications of regenerative medicine. In addition to animal experiments, results of research on human tissues and organs are included.