Old Age New Science

Between 1870 and 1940, life expectancy in the United States skyrocketed while the percentage of senior citizens age sixty-five and older more than doubled—a phenomenon owed largely to innovations in medicine and public health. At the same time, the Great Depression was a major tipping point for age discrimination and poverty in the West: seniors were living longer and retiring earlier, but without adequate means to support themselves and their families. The economic disaster of the 1930s alerted scientists, who were actively researching the processes of aging, to the profound social implications of their work—and by the end of the 1950s, the field of gerontology emerged. Old Age, New Science explores how a group of American and British life scientists contributed to gerontology’s development as a multidisciplinary field. It examines the foundational “biosocial visions” they shared, a byproduct of both their research and the social problems they encountered. Hyung Wook Park shows how these visions shaped popular discourses on aging, directly influenced the institutionalization of gerontology, and also reflected the class, gender, and race biases of their founders.

“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

A groundbreaking, revisionist account of the importance of the history of philosophy to intellectual change - scientific, philosophical and religious - in seventeenth-century England.

“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

___ ***SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE 2022*** Did you know that we can lead longer and healthier lives by making simple changes right now? Professor Rose Anne Kenny has 35 years of experience at the forefront of ageing medicine. In Age Proof, she draws on her own pioneering research and the latest evidence to demystify why we age and shows us that 80% of our ageing biology is within our control: we can not only live longer lives but become happier and healthier deep into our later years. Effortlessly distilling scientific theory into practical advice that we can apply to our everyday lives, Professor Kenny examines the impact that food, genetics, friendships, purpose, sex, exercise and laughter have on how our cells age. This illuminating book will show you the steps you can take to stay younger for longer - and will prove that you really are just as young as you feel.

A revolutionary examination of why we age, what it means for our health, and how we just might be able to fight it. In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction. When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection. This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.

This unique book represents the first multi-disciplinary examination of ageing, covering everything from basic cell biology, to social participation in later life, to the representations of old age in the arts and literature. A comprehensive introductory text about the latest scientific evidence on ageing, the book draws on the pioneering New Dynamics of Ageing Programme, the UK’s largest research programme in ageing. This programme brought together leading academics from across the arts and humanities, social and biological sciences and fields of engineering and medical research, to study how ageing is changing and the ways in which this process can be made more beneficial to both individuals and society. Comprising individual, local, national and global perspectives, this book will appeal to everyone with an interest in one of the greatest challenges facing the world – our own ageing.