On Par

A resource for everyday golfers draws on the author's consultations with instructors, players, caddies, psychiatrists, economists, and Zen masters to share lighthearted, therapeutic advice on essential game skills.

Andrea Hoffpauir can’t do anything right. But she’s ready to prove to everyone that she’s up to any challenge. She’s never been good enough for her father. Her trophy-wife mother is so self-centered that she often forgets Andrea exists. And her best friend Vicky hasn’t forgiven her for the monumental mistake she made. Life keeps kicking her down, and quite frankly, she’s over it. When her older brother Brendan backs out of the father son golf tournament at the club, Andrea volunteers to take his place. She’s determined to show her dad that she’s not as useless as he thinks, and that she’s an excellent golfer. Even if her father doesn’t want to be seen with her on the links or off. During a round at the club, Erik Perday, Vicky’s mortal enemy, acts like a normal human being, and Andrea wonders if all is not what it seems. He’s not the jerk she’s always believed him to be, at least not around her. Is there more to Erik Perday? Andrea feels like her life is spinning, but she’s not sure if it’s spinning out of control or if she's headed in the right direction. She’s determined to prove to everyone that she’s good enough ... including herself. On Par is the final book in the Girls of Summer series, a young adult sports romance. If you love sports, strong female characters, and coming of age stories, then you’ll love this fast-paced series about girls who defy the stereotypes. Each book can be read as a standalone. One-click this young adult coming of age romance today.

A few verses written to relieve personal struggle and stress, an expression of emotions that forces connection. One verse is brutal, the other tender. Has poetic mood swings, poetic madness, poetic blasphemy, poetic godly mysticism. These are the words of the poet about an epic journey with pen as his sword and paper as his shield. A few painful expressions of poetry that will bring joy and release stress, an honest form of expression.

Par-4 is a naturally occurring tumor suppressor. Studies have indicated that overexpression of Par-4 selectively induces apoptosis in cancer cells while leaving normal, health, cells unaffected. Mechanisms contributing to this cancer-selective action of Par-4 have been associated with PKA activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. On the other hand, endogenous Par-4 sensitizes cells to the action of a broad range of apoptotic inducers acting via the extrinsic and intrinsic pathways. A number of binding partners of Par-4 have been identified and shown to regulate Par-4 function in cancer and other diseases, such as Alzheimer’s and major depression. Recent studies have recognized a number of natural products, dietary supplements, synthetic molecules and FDA-approved drugs that induce the secretion of Par-4 protein to cause apoptosis in primary or metastatic tumors, one of which is in clinical trials. More than 50 different laboratories worldwide are involved in Par-4 based research of this unique protein that has progressed from the bench to clinical trials. This second, companion volume will provide a comprehensive overview of Par-4’s role in cancer and other diseases. Chapters are written by leading researchers, and will be useful for a broad audience across the scientific community, particularly students and trainees, who are the next generation of scientists and clinicians to participate in new studies and discoveries on Par-4.